ACSL6 (NM_001205247) Human Tagged ORF Clone

CAT#: RG234715

ACSL6 (GFP-tagged) - Homo sapiens acyl-CoA synthetase long-chain family member 6 (ACSL6), transcript variant 3

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: ACSL6
• Synonyms: ACS2; FACL6; LACS2; LACS5; LACS 6
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG234715 representing NM_001205247
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTGACCTTCTTCCTCGTGTCGGGGGGCTCCCTCTGGCTATTCGTAGAGTTTGTCCTCTCACTTCTGG
  AGAAGATGCAGACACAGGAGATCCTGAGGATACTGCGACTGCCTGAGCTAGGTGACTTGGGACAGTTTTT
  CCGCAGCCTCTCGGCCACCACCCTCGACAGTGGCGGGGCACGGCGATCTGTGATTGGGTCTGGCCCTCAG
  CTACTTACCCACTACTATGATGATGCCCGGACCATGTACCAGGTGTTCCGCCGTGGGCTTAGCATCTCAG
  GGAATGGGCCCTGTCTTGGTTTCAGGAAGCCTAAGCAGCCTTACCAGTGGCTGTCCTACCAGGAGGTGGC
  CGACAGGGCTGAATTTCTGGGGTCCGGACTTCTCCAGCACAATTGTAAAGCATGCACTGATCAGTTTATT
  GGTGTTTTTGCACAAAATCGGCCAGAGTGGATCATTGTGGAGCTGGCCTGCTACACATATTCCATGGTGG
  TGGTCCCGCTCTATGACACCCTGGGCCCTGGGGCTATCCGCTACATCATCAATACAGCGGACATCAGCAC
  CGTGATTGTGGACAAACCTCAGAAGGCTGTGCTTCTGCTAGAGCATGTGGAGAGGAAGGAGACTCCAGGC
  CTCAAGCTGATCATCCTCATGGACCCATTCGAAGAAGCCCTGAAAGAGAGAGGGCAGAAGTGCGGGGTGG
  TCATTAAGTCCATGCAGGCCGTGGAGGACTGTGGCCAAGAGAATCACCAGGCTCCTGTGCCCCCGCAGCC
  TGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCAT
  GGGAACGTGGTGGCTGATTTCTCAGGCTTTCTGAAAGTGACAGAGAGTCAGTGGGCTCCCACTTGTGCGG
  ATGTGCACATTTCCTATTTGCCTTTAGCACACATGTTTGAGCGAATGGTGCAGTCTGTCGTCTATTGCCA
  CGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAGGCTCTATGCCCC
  ACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACAC
  CATTAAAGCGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAG
  GAATGATAGTATCTGGGATGAACTCTTCTTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATG
  ATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGG
  TTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACCTC
  AGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGG
  GCCTGCAAAGGAGAGGGAGAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAG
  ACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCGGC
  AGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAATATGTTGCACCC
  GAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAA
  AGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAAT
  TGAAGGAACATATGCAGATCTCTGCACAAATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGG
  TTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATTCACATCCATTCTGACATGTTCT
  CAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAA
  ACAAATAGAAGAGCTTTACTCAATCTCCATG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG234715 representing NM_001205247
  Red=Cloning site Green=Tags(s)
  
  MLTFFLVSGGSLWLFVEFVLSLLEKMQTQEILRILRLPELGDLGQFFRSLSATTLDSGGARRSVIGSGPQ
  LLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFI
  GVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPG
  LKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTH
  GNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCP
  TIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRM
  IVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYW
  ACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAP
  EKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVR
  LGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKAKRPELREYFKKQIEELYSISM
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001205247
• ORF Size: 2061 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001205247.1, NP_001192176.1
• RefSeq Size: 6449
• RefSeq ORF: 2064
• Locus ID: 23305
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway
• Gene Summary: The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]