Heme oxygenase 2 (HMOX2) (NM_001286271) Human Tagged ORF Clone

CAT#: RG237209

HMOX2 (GFP-tagged) - Human heme oxygenase (decycling) 2 (HMOX2), transcript variant 9

Specifications

Product Data

• Tag: TurboGFP
• Symbol: HMOX2
• Synonyms: HO-2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG237209 representing NM_001286271.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCTGACCTCTCGGAGCTCCTGAAGGAAGGGACCAAGGAAGCACACGACCGGGCAGAAAACACCCAG
  TTTGTCAAGGACTTCTTGAAAGGCAACATTAAGAAGGAGCTGTTTAAGCTGGCCACCACGGCACTTTAC
  TTCACATACTCAGCCCTCGAGGAGGAAATGGAGCGCAACAAGGACCATCCAGCCTTTGCCCCTTTGTAC
  TTCCCCATGGAGCTGCACCGGAAGGAGGCGCTGACCAAGGACATGGAGTATTTCTTTGGTGAAAACTGG
  GAGGAGCAGGTGCAGTGCCCCAAGGCTGCCCAGAAGTACGTGGAGCGGATCCACTACATAGGGCAGAAC
  GAGCCGGAGCTACTGGTGGCCCATGCATACACCCGCTACATGGGGGATCTCTCGGGGGGCCAGGTGCTG
  AAGAAGGTGGCCCAGCGAGCACTGAAACTCCCCAGCACAGGGGAAGGGACCCAGTTCTACCTGTTTGAG
  AATGTGGACAATGCCCAGCAGTTCAAGCAGCTCTACCGGGCCAGGATGAACGCCCTGGACCTGAACATG
  AAGACCAAAGAGAGGATCGTGGAGGAGGCCAACAAGGCTTTTGAGTATAACATGCAGATATTCAATGAA
  CTGGACCAGGCCGGCTCCACACTGGCCAGAGAGACCTTGGAGGATGGGTTCCCTGTACACGATGGGAAA
  GGAGACATGCGTAAATGCCCTTTCTACGCTGCTGAACAAGACAAAGGTGCCCTGGAGGGCAGCAGCTGT
  CCCTTCCGAACAGCTATGGCTGTGCTGAGGAAGCCCAGCCTCCAGTTCATCCTGGCCGCTGGTGTGGCC
  CTAGCTGCTGGACTCTTGGCCTGGTACTACATG
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG237209
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLY
  FPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVL
  KKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNE
  LDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVA
  LAAGLLAWYYM
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001286271
• ORF Size: 861 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001286271.1, NP_001273200.1
• RefSeq Size: 1627 bp
• RefSeq ORF: 864 bp
• Locus ID: 3163
• Cytogenetics: 16p13.3
• Protein Families: Transmembrane
• Protein Pathways: Porphyrin and chlorophyll metabolism
• MW: 33.3 kDa
• Gene Summary: 'Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]'