ALDH1A3 (NM_001293815) Human Tagged ORF Clone

CAT#: RG238016

ALDH1A3 (GFP-tagged) - Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), transcript variant 2

Specifications

Product Data

• Tag: TurboGFP
• Symbol: ALDH1A3
• Synonyms: ALDH1A6; ALDH6; MCOP8; RALDH3
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238016 representing NM_001293815.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCCACCGCTAACGGGGCCGTGGAAAACGGGCAGCCGGACAGGAAGCCGCCGGCCCTGCCGCGCCCC
  ATCCGCAACCTGGAGGTCAAGTTCACCAAGATATTTATCAACAATGAATGGCACGAATCCAAGAGTGGG
  AAAAAGTTTGCTACATGTAACCCTTCAACTCGGGAGCAAATATGTGAAGTGGAAGAAGGAGATAAGCCC
  GACGTGGACAAGGCTGTGGAGGCTGCACAGGTTGCCTTCCAGAGGGGCTCGCCATGGCGCCGGCTGGAT
  GCCCTGAGTCGTGGGCGGCTGCTGCACCAGCTGGCTGACCTGGTGGAGAGGGACCGCGCCACCTTGGCC
  GCCGGGTTCCCTCCAGGAGTGGTGAACATTGTGCCAGGATTCGGGCCCACAGTGGGAGCAGCAATTTCT
  TCTCACCCTCAGATCAACAAGATCGCCTTCACCGGCTCCACAGAGGTTGGAAAACTGGTTAAAGAAGCT
  GCGTCCCGGAGCAATCTGAAGCGGGTGACGCTGGAGCTGGGGGGGAAGAACCCCTGCATCGTGTGTGCG
  GACGCTGACTTGGACTTGGCAGTGGAGTGTGCCCATCAGGGAGTGTTCTTCAACCAAGGCCAGTGTTGC
  ACGGCAGCCTCCAGGGTGTTCGTGGAGGAGCAGGTCTACTCTGAGTTTGTCAGGCGGAGCGTGGAGTAT
  GCCAAGAAACGGCCCGTGGGAGACCCCTTCGATGTCAAAACAGAACAGGGGCCTCAGATTGATCAAAAG
  CAGTTCGACAAAATCTTAGAGCTGATCGAGAGTGGGAAGAAGGAAGGGGCCAAGCTGGAATGCGGGGGC
  TCAGCCATGGAAGACAAGGGGCTCTTCATCAAACCCACTGTCTTCTCAGAAGTCACAGACAACATGCGG
  ATTGCCAAAGAGGAGATTTTCGGGCCAGTGCAACCAATACTGAAGTTCAAAAGTATCGAAGAAGTGATA
  AAAAGAGCGAATAGCACCGACTATGGACTCACAGCAGCCGTGTTCACAAAAAATCTCGACAAAGCCCTG
  AAGTTGGCTTCTGCCTTAGAGTCTGGAACGGTCTGGATCAACTGCTACAACGCCCTCTATGCACAGGCT
  CCATTTGGTGGCTTTAAAATGTCAGGAAATGGCAGAGAACTAGGTGAATACGCTTTGGCCGAATACACA
  GAAGTGAAAACTGTCACCATCAAACTTGGCGACAAGAACCCC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238016
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKP
  DVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAAGFPPGVVNIVPGFGPTVGAAIS
  SHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCC
  TAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG
  SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKAL
  KLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001293815
• ORF Size: 1215 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001293815.2
• RefSeq Size: 3301 bp
• RefSeq ORF: 1218 bp
• Locus ID: 220
• Cytogenetics: 15q26.3
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism
• MW: 44.7 kDa
• Gene Summary: 'This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]'