CDC2L6 (CDK19) (NM_001300960) Human Tagged ORF Clone

CAT#: RG238346

CDK19 (GFP-tagged) - Human cyclin-dependent kinase 19 (CDK19), transcript variant 2

Specifications

Product Data

• Tag: TurboGFP
• Symbol: CDK19
• Synonyms: bA346C16.3; CDC2L6; CDK11
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238346 representing NM_001300960.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGATTATGATTTCAAGGCGAAGCTGGCGGCGGAGCGGGAGCGGGTGGAGGATTTGTTTGAGTACGAA
  GGGTGCAAAGTGGGACGCGGCACCTACGGTCACGTCTACAAGGCGAGGCGGAAAGATGGAAAAGATGAA
  AAGGAATATGCATTGAAGCAAATTGAAGGCACAGGAATATCCATGTCGGCTTGTAGAGAGATTGCACTT
  TTGCGAGAATTGAAGCACCCTAATGTGATTGCATTGCAGAAGGTGTTCCTTTCTCACAGTGACAGGAAG
  GTATGGCTGCTGTTTGATTATGCAGAGCATGACTTGTGGCATATTATTAAGTTTCACCGTGCATCAAAA
  GCAAATAAAAAGCCCATGCAGTTGCCAAGATCTATGGTTAAATCCTTACTTTACCAGATTCTTGATGGT
  ATCCATTACCTCCATGCAAATTGGGTGCTTCACAGAGACTTGAAACCAGCAAATATCCTAGTAATGGGA
  GAAGGTCCTGAGAGGGGGAGAGTCAAAATAGATATATGGGCAATAGGTTGTATATTTGCTGAATTGTTG
  ACTTCGGAACCTATTTTTCACTGTCGTCAGGAAGATATAAAAACAAGCAATCCCTTTCATCATGATCAA
  CTGGATCGGATATTTAGTGTCATGGGGTTTCCTGCAGATAAAGACTGGGAAGATATTAGAAAGATGCCA
  GAATATCCCACACTTCAAAAAGACTTTAGAAGAACAACGTATGCCAACAGTAGCCTCATAAAGTACATG
  GAGAAACACAAGGTCAAGCCTGACAGCAAAGTGTTCCTCTTGCTTCAGAAACTCCTGACCATGGATCCA
  ACCAAGAGAATTACCTCGGAGCAAGCTCTGCAGGATCCCTATTTTCAGGAGGACCCTTTGCCAACATTA
  GATGTATTTGCCGGCTGCCAGATTCCATACCCCAAACGAGAATTCCTTAATGAAGATGATCCTGAAGAA
  AAAGGTGACAAGAATCAGCAACAGCAGCAGAACCAGCATCAGCAGCCCACAGCCCCTCCACAGCAGGCA
  GCAGCCCCTCCACAGGCGCCCCCACCACAGCAGAACAGCACCCAGACCAACGGGACCGCAGGTGGGGCT
  GGGGCCGGGGTCGGGGGCACCGGAGCAGGGTTGCAGCACAGCCAGGACTCCAGCCTGAACCAGGTGCCT
  CCAAACAAGAAGCCACGGCTAGGGCCTTCAGGCGCAAACTCAGGTGGACCTGTGATGCCCTCGGATTAT
  CAGCACTCCAGTTCTCGCCTGAATTACCAAAGCAGCGTTCAGGGATCCTCTCAGTCCCAGAGCACACTT
  GGCTACTCTTCCTCGTCTCAGCAGAGCTCACAGTACCACCCATCTCACCAGGCCCACCGGTAC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238346
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIAL
  LRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDG
  IHYLHANWVLHRDLKPANILVMGEGPERGRVKIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQ
  LDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDP
  TKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQA
  AAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDY
  QHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001300960
• ORF Size: 1374 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001300960.2
• RefSeq Size: 6114 bp
• RefSeq ORF: 1377 bp
• Locus ID: 23097
• Cytogenetics: 6q21
• Protein Families: Druggable Genome, Protein Kinase
• MW: 52.3 kDa
• Gene Summary: This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]