LILRB2 (NM_001278405) Human Tagged ORF Clone
CAT#: RG238639
- TrueORF®
LILRB2 (GFP-tagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 (LILRB2), transcript variant 5
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Specifications
Product Data | |
Tag | TurboGFP |
Symbol | LILRB2 |
Synonyms | CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG238639 representing NM_001278405.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACCCCCATCGTCACAGTCCTGATCTGTCTCGGGCTGAGTCTGGGCCCCAGGACCCGCGTGCAGACA GGGACCATCCCCAAGCCCACCCTGTGGGCTGAGCCAGACTCTGTGATCACCCAGGGGAGTCCCGTCACC CTCAGTTGTCAGGGGAGCCTTGAAGCCCAGGAGTACCGTCTATATAGGGAGAAAAAATCAGCATCTTGG ATTACACGGATACGACCAGAGCTTGTGAAGAACGGCCAGTTCCACATCCCATCCATCACCTGGGAACAC ACAGGGCGATATGGCTGTCAGTATTACAGCCGCGCTCGGTGGTCTGAGCTCAGTGACCCCCTGGTGCTG GTGATGACAGGAGCCTACCCAAAACCCACCCTCTCAGCCCAGCCCAGCCCTGTGGTGACCTCAGGAGGA AGGGTGACCCTCCAGTGTGAGTCACAGGTGGCATTTGGCGGCTTCATTCTGTGTAAGGAAGGAGAAGAT GAACACCCACAATGCCTGAACTCCCAGCCCCATGCCCGTGGGTCGTCCCGCGCCATCTTCTCCGTGGGC CCCGTGAGCCCGAATCGCAGGTGGTCGCACAGGTGCTATGGTTATGACTTGAACTCTCCCTATGTGTGG TCTTCACCCAGTGATCTCCTGGAGCTCCTGGTCCCAGGTGTTTCTAAGAAGCCATCACTCTCAGTGCAG CCGGGTCCTGTCATGGCCCCTGGGGAAAGCCTGACCCTCCAGTGTGTCTCTGATGTCGGCTATGACAGA TTTGTTCTGTACAAGGAGGGGGAACGTGACCTTCGCCAGCTCCCTGGCCGGCAGCCCCAGGCTGGGCTC TCCCAGGCCAACTTCACCCTGGGCCCTGTGAGCCGCTCCTACGGGGGCCAGTACAGATGCTACGGTGCA CACAACCTCTCCTCTGAGTGCTCGGCCCCCAGCGACCCCCTGGACATCCTGATCACAGGACAGATCCGT GGCACACCCTTCATCTCAGTGCAGCCAGGCCCCACAGTGGCCTCAGGAGAGAACGTGACCCTGCTGTGT CAGTCATGGCGGCAGTTCCACACTTTCCTTCTGACCAAGGCGGGAGCAGCTGATGCCCCACTCCGTCTA AGATCAATACACGAATATCCTAAGTACCAGGCTGAATTCCCCATGAGTCCTGTGACCTCAGCCCACGCG GGGACCTACAGGTGCTACGGCTCACTCAACTCCGACCCCTACCTGCTGTCTCACCCCAGTGAGCCCCTG GAGCTCGTGGTCTCAGGACCCTCCATGGGTTCCAGCCCCCCACCCACCGGTCCCATCTCCACACCTGCA GGCCCTGAGGACCAGCCCCTCACCCCCACTGGGTCGGATCCCCAAAGTGGTCTGGGAAGGCACCTGGGG GTTGTGATCGGCATCTTGGTGGCCGTCGTCCTACTGCTCCTCCTCCTCCTCCTCCTCTTCCTCATCCTC CGACATCGACGTCAGGGCAAACACTGGACATCGAGTCCAGCCCAGCTGCCGACGCCCAGGAAGAAAACC TCTATGCTGCCG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG238639
Blue=ORF Red=Cloning site Green=Tag(s) MTPIVTVLICLGLSLGPRTRVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASW ITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGG RVTLQCESQVAFGGFILCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVW SSPSDLLELLVPGVSKKPSLSVQPGPVMAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGL SQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLC QSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPL ELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLLLLLFLIL RHRRQGKHWTSSPAQLPTPRKKTSMLP TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001278405 |
ORF Size | 1530 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reference Data | |
RefSeq | NM_001278405.2, NP_001265334.2 |
RefSeq Size | 2646 bp |
RefSeq ORF | 1533 bp |
Locus ID | 10288 |
Cytogenetics | 19q13.42 |
Protein Families | Transmembrane |
MW | 55.9 kDa |
Gene Summary | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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