MPP2 (NM_001278375) Human Tagged ORF Clone

CAT#: RG238808

MPP2 (GFP-tagged) - Human membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (MPP2), transcript variant 7

Specifications

Product Data

• Tag: TurboGFP
• Symbol: MPP2
• Synonyms: DLG2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238808 representing NM_001278375.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGCAGCAAGTCCTGGACAACTTGGGATCCCTCCCCAGTGCCACGGGGGCTGCAGAGCTGGACCTGATC
  TTCCTTCGAGGCATTATGGAAAGTCCCATAGTAAGATCCCTGGCCAAGGCCCATGAGAGGCTGGAGGAG
  ACGAAGCTGGAGGCCGTGAGAGACAACAACCTGGAGCTGGTGCAGGAGATCCTGCGGGACCTGGCGCAG
  CTGGCTGAGCAGAGCAGCACAGCCGCCGAGCTGGCCCACATCCTCCAGGAGCCCCACTTCCAGTCCCTC
  CTGGAGACGCACGACTCTGTGGCCTCAAAGACCTATGAGACACCACCCCCCAGCCCTGGCCTGGACCCT
  ACATTCAGCAACCAGCCTGTACCTCCCGATGCTGTGCGCATGGTGGGCATCCGCAAGACAGCCGGAGAA
  CATCTGGGTGTAACGTTCCGCGTGGAGGGCGGCGAGCTGGTGATCGCGCGCATTCTGCATGGGGGCATG
  GTGGCTCAACAAGGCCTGCTGCATGTGGGTGACATCATCAAGGAGGTGAACGGGCAGCCAGTGGGCAGT
  GACCCCCGCGCACTGCAGGAGCTCCTGCGCAATGCCAGTGGCAGTGTCATCCTCAAGATCCTGCCCAGC
  TACCAGGAGCCCCATCTGCCCCGCCAGGTATTTGTGAAATGTCACTTTGACTATGACCCGGCCCGAGAC
  AGCCTCATCCCCTGCAAGGAAGCAGGCCTGCGCTTCAACGCCGGGGACTTGCTCCAGATCGTAAACCAG
  GATGATGCCAACTGGTGGCAGGCATGCCATGTCGAAGGGGGCAGTGCTGGGCTCATTCCCAGCCAGCTG
  CTGGAGGAGAAGCGGAAAGCATTTGTCAAGAGGGACCTGGAGCTGACACCAAACTCAGGGACCCTATGC
  GGCAGCCTTTCAGGAAAGAAAAAGAAGCGAATGATGTATTTGACCACCAAGAATGCAGAGTTTGACCGT
  CATGAGCTGCTCATTTATGAGGAGGTGGCCCGCATGCCCCCGTTCCGCCGGAAAACCCTGGTACTGATT
  GGGGCTCAGGGCGTGGGACGGCGCAGCCTGAAGAACAAGCTCATCATGTGGGATCCAGATCGCTATGGC
  ACCACGGTGCCCTACACCTCCCGGCGGCCGAAAGACTCAGAGCGGGAAGGTCAGGGTTACAGCTTTGTG
  TCCCGTGGGGAGATGGAGGCTGACGTCCGTGCTGGGCGCTACCTGGAGCATGGCGAATACGAGGGCAAC
  CTGTATGGCACACGTATTGACTCCATCCGGGGCGTGGTCGCTGCTGGGAAGGTGTGCGTGCTGGATGTC
  AACCCCCAGGCGGTGAAGGTGCTACGAACGGCCGAGTTTGTCCCTTACGTGGTGTTCATCGAGGCCCCA
  GACTTCGAGACCCTGCGGGCCATGAACAGGGCTGCGCTGGAGAGTGGAATATCCACCAAGCAGCTCACG
  GAGGCGGACCTGAGACGGACAGTGGAGGAGAGCAGCCGCATCCAGCGGGGCTACGGGCACTACTTTGAC
  CTCTGCCTGGTCAATAGCAACCTGGAGAGGACCTTCCGCGAGCTCCAGACAGCCATGGAGAAGCTACGG
  ACAGAGCCCCAGTGGGTGCCTGTCAGCTGGGTGTAC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238808
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MQQVLDNLGSLPSATGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEAVRDNNLELVQEILRDLAQ
  LAEQSSTAAELAHILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGE
  HLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRNASGSVILKILPS
  YQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGSAGLIPSQL
  LEEKRKAFVKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLI
  GAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGN
  LYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGISTKQLT
  EADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPVSWVY
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001278375
• ORF Size: 1623 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001278375.1, NP_001265304.1
• RefSeq Size: 4391 bp
• RefSeq ORF: 1626 bp
• Locus ID: 4355
• Cytogenetics: 17q21.31
• Protein Families: Druggable Genome
• MW: 61 kDa
• Gene Summary: ' Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008]'