PXK (NM_001289096) Human Tagged ORF Clone

CAT#: RG238838

PXK (GFP-tagged) - Human PX domain containing serine/threonine kinase (PXK), transcript variant 3

Specifications

Product Data

• Tag: TurboGFP
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238838 representing NM_001289096.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCCTTCATGGAGAAGCCGCCAGCCGGCAAGGTGCTGCTGGACGACACGGTGCCGCTGACAGCAGCC
  ATCGAGGCGAGCCAGAGCCTGCAGTCCCACACGATTGCAGGCCTAAGTCTACCTCTTCCTCCCAAAAAA
  TTGATTGGTAACATGGATCGTGAATTCATAGCTGAAAGGCAGAAAGGTCTTCAGAACTATCTCAACGTG
  ATCACAACAAATCATATCTTGTCTAATTGTGAGCTGGTTAAGAAGTTTTTAGATCCAAACAACTATTCC
  GCAAACTATACTGAGATTGCCTTGCAACAGGTTTCCATGTTCTTCCGATCAGAACCAAAGTGGGAGGTG
  GTGGAACCTTTGAAAGACATAGGTTGGAGAATAAGGAAGAAATATTTCTTGATGAAGATTAAAAATCAG
  CCAAAGGAACGGCTAGTGTTAAGCTGGGCTGACCTTGGCCCAGACAAGTATTTGTCAGATAAAGATTTT
  CAGTGTCTAATCAAACTTCTGCCTTCTTGTTTGCACCCTTACATCTATCGGGTTACCTTTGCCACAGCT
  AATGAATCCTCAGCGTTGCTAATTAGGATGTTTAACGAAAAGGGAACATTGAAGGATCTGATCTACAAG
  GCAAAACCAAAAGACCCATTTCTAAAGAAGTACTGCAACCCTAAGAAGATTCAGGGCCTGGAACTCCAG
  CAAATAAAAACATATGGACGGCAAATATTAGAGGTACTGAAGTTTCTTCATGACAAGGGATTCCCTTAT
  GGGCATCTTCACGCCTCCAATGTGATGCTCGATGGGGACACTTGCCGGCTGCTGGACCTTGAGAATTCC
  TTATTGGGCCTGCCTTCCTTCTACCGATCTTATTTTTCACAATTCAGGAAAATCAATACATTGGAAAGT
  GTGGATGTCCACTGCTTTGGCCACTTACTGTATGAAATGACTTATGGACGACCGCCAGACTCGGTGCCT
  GTGGACTCCTTCCCTCCTGCCCCGTCCATGGCTGTGGTGGCCGTGTTGGAGTCTACGCTGTCTTGTGAA
  GCCTGTAAAAATGGCATGCCTACCATCTCCCGGCTCTTACAGATGCCATTATTCAGCGATGTTTTACTA
  ACCACTTCTGAAAAACCACAGTTTAAGATCCCTACAAAGTTAAAAGAGGCATTGAGAATTGCCAAAGAA
  TGTATAGAGAAGAGACTAATTGAGGAACAGAAACAGATTCACCAGCATCGAAGACTGACAAGAGCTCAG
  TCCCACCATGGATCTGAGGAGGAAAGAAAAAAAAGAAAGATTTTAGCTCGAAAGAAGTCAAAACGATCT
  GCTCTTGAAAATAGTGAAGAGCATTCAGCGAAGTACAGCAACTCCAATAATTCAGCAGGATCTGGGGCC
  AGCTCACCTCTCACGTCCCCGTCATCGCCAACTCCACCCTCTACATCAGGGATATCTGCATTACCTCCA
  CCTCCTCCACCTCCACCACCACCAGCAGCTCCCTTGCCTCCTGCGAGCACCGAGGCACCTGCCCAGCTC
  TCGTCTCAGGCTGTGAATGGCATGAGCCGAGGGGCCTTGCTCAGCTCCATCCAGAATTTCCAAAAAGGA
  ACTTTGAGGAAAGCCAAAACCTGTGATCACAGTGCTCCGAAGATCGGC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238838
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNV
  ITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQ
  PKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYK
  AKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDTCRLLDLENS
  LLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPAPSMAVVAVLESTLSCE
  ACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALRIAKECIEKRLIEEQKQIHQHRRLTRAQ
  SHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGISALPP
  PPPPPPPPAAPLPPASTEAPAQLSSQAVNGMSRGALLSSIQNFQKGTLRKAKTCDHSAPKIG
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289096
• ORF Size: 1635 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001289096.1, NP_001276025.1
• RefSeq Size: 2921 bp
• RefSeq ORF: 1638 bp
• Locus ID: 54899
• Cytogenetics: 3p14.3
• Protein Families: Druggable Genome, Protein Kinase
• MW: 61.4 kDa
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]