PXK (NM_001289095) Human Tagged ORF Clone

CAT#: RG238909

PXK (GFP-tagged) - Human PX domain containing serine/threonine kinase (PXK), transcript variant 2

Specifications

Product Data

• Tag: TurboGFP
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238909 representing NM_001289095.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGCCTTCATGGAGAAGCCGCCAGCCGGCAAGGTGCTGCTGGACGACACGGTGCCGCTGACAGCAGCC
  ATCGAGGCGAGCCAGAGCCTGCAGTCCCACACGATTGTTAGAAGATACAGTGACTTTGATTTGCTTAAC
  AACAGCTTACAGATTGCAGGCCTAAGTCTACCTCTTCCTCCCAAAAAATTGATTGGTAACATGGATCGT
  GAATTCATAGCTGAAAGGCAGAAAGGTCTTCAGAACTATCTCAACGTGATCACAACAAATCATATCTTG
  TCTAATTGTGAGCTGGTTAAGAAGTTTTTAGATCCAAACAACTATTCCGCAAACTATACTGAGATTGCC
  TTGCAACAGGTTTCCATGTTCTTCCGATCAGAACCAAAGTGGGAGGTGGTGGAACCTTTGAAAGACATA
  GGTTGGAGAATAAGGAAGAAATATTTCTTGATGAAGATTAAAAATCAGCCAAAGGAACGGCTAGTGTTA
  AGCTGGGCTGACCTTGGCCCAGACAAGTATTTGTCAGATAAAGATTTTCAGTGTCTAATCAAACTTCTG
  CCTTCTTGTTTGCACCCTTACATCTATCGGGTTACCTTTGCCACAGCTAATGAATCCTCAGCGTTGCTA
  ATTAGGATGTTTAACGAAAAGGGAACATTGAAGGATCTGATCTACAAGGCAAAACCAAAAGACCCATTT
  CTAAAGAAGTACTGCAACCCTAAGAAGATTCAGGGCCTGGAACTCCAGCAAATAAAAACATATGGACGG
  CAAATATTAGAGGTACTGAAGTTTCTTCATGACAAGGGATTCCCTTATGGGCATCTTCACGCCTCCAAT
  GTGATGCTCGATGGGGACACTTGCCGGCTGCTGGACCTTGAGAATTCCTTATTGGGCCTGCCTTCCTTC
  TACCGATCTTATTTTTCACAATTCAGGAAAATCAATACATTGGAAAGTGTGGATGTCCACTGCTTTGGC
  CACTTACTGTATGAAATGACTTATGGACGACCGCCAGACTCGGTGCCTGTGGACTCCTTCCCTCCTGCC
  CCGTCCATGGCTGTGGTGGCCGTGTTGGAGTCTACGCTGTCTTGTGAAGCCTGTAAAAATGGCATGCCT
  ACCATCTCCCGGCTCTTACAGATGCCATTATTCAGCGATGTTTTACTAACCACTTCTGAAAAACCACAG
  TTTAAGATCCCTACAAAGTTAAAAGAGGCATTGAGAATTGCCAAAGAATGTATAGAGAAGAGACTAATT
  GAGGAACAGAAACAGATTCACCAGCATCGAAGACTGACAAGAGCTCAGTCCCACCATGGATCTGAGGAG
  GAAAGAAAAAAAAGAAAGATTTTAGCTCGAAAGAAGTCAAAACGATCTGCTCTTGAAAATAGTGAAGAG
  CATTCAGCGAAGTACAGCAACTCCAATAATTCAGGATCTGGGGCCAGCTCACCTCTCACGTCCCCGTCA
  TCGCCAACTCCACCCTCTACATCAGCTGCCTTAGGTTTGAGTAAAAGATGTAAAGAAAGGGATATCTGC
  ATTACCTCCACCTCCTCCACCTCCACCACCACCAGCAGCTCCCTTGCCTCCTGCGAGCACCGAGGCACC
  TGCCCAGCTCTCGTCTCAGGCTGTGAATGGCATGAGCCGAGGGGCCTTGCTCAGCTCCATCCAGAATTT
  CCAAAAAGGAACTTTGAGGAAAGCCAAAACCTG
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238909
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDR
  EFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDI
  GWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALL
  IRMFNEKGTLKDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASN
  VMLDGDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPA
  PSMAVVAVLESTLSCEACKNGMPTISRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALRIAKECIEKRLI
  EEQKQIHQHRRLTRAQSHHGSEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSGSGASSPLTSPS
  SPTPPSTSAALGLSKRCKERDICITSTSSTSTTTSSSLASCEHRGTCPALVSGCEWHEPRGLAQLHPEF
  PKRNFEESQNL
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289095
• ORF Size: 1689 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001289095.1, NP_001276024.1
• RefSeq Size: 3000 bp
• RefSeq ORF: 1692 bp
• Locus ID: 54899
• Cytogenetics: 3p14.3
• Protein Families: Druggable Genome, Protein Kinase
• MW: 64.2 kDa
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]