Rho GTPase activating protein 24 (ARHGAP24) (NM_001287805) Human Tagged ORF Clone

CAT#: RG239254

ARHGAP24 (GFP-tagged) - Human Rho GTPase activating protein 24 (ARHGAP24), transcript variant 4

Specifications

Product Data

• Tag: TurboGFP
• Symbol: ARHGAP24
• Synonyms: FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG239254 representing NM_001287805.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGTTTGTGCAAGGAGGCGATCGAGATCGGATGACAGCAAATCATGAAAGCTACCTCCTCATGGCAAGC
  ACCCAGAATGATATGGAAGACTGGGTGAAGTCAATCCGCCGAGTCATATGGGGACCTTTCGGAGGAGGC
  ATTTTTGGACAGAAACTGGAGGATACTGTTCGTTATGAGAAGAGATATGGGAACCGTCTGGCTCCGATG
  TTGGTGGAGCAGTGCGTGGACTTTATCCGACAAAGGGGGCTGAAAGAAGAGGGTCTCTTTCGACTGCCA
  GGCCAGGCTAATCTTGTTAAGGAGCTCCAAGATGCCTTTGACTGTGGGGAGAAGCCATCATTTGACAGC
  AACACAGATGTACACACGGTGGCATCACTTCTTAAGCTGTACCTCCGAGAACTTCCAGAACCAGTTATT
  CCTTATGCGAAGTATGAAGATTTTTTGTCATGTGCCAAACTGCTCAGCAAGGAAGAGGAAGCAGGTGTT
  AAGGAATTAGCAAAGCAGGTGAAGAGTTTGCCAGTGGTAAATTACAACCTCCTCAAGTATATTTGCAGA
  TTCTTGGATGAAGTACAGTCCTACTCGGGAGTTAACAAAATGAGTGTGCAGAACTTGGCAACGGTCTTT
  GGTCCTAATATCCTGCGCCCCAAAGTGGAAGATCCTTTGACTATCATGGAGGGCACTGTGGTGGTCCAG
  CAGTTGATGTCAGTGATGATTAGCAAACATGATTGCCTCTTTCCCAAAGATGCAGAACTACAAAGCAAG
  CCCCAAGATGGAGTGAGCAACAACAATGAAATTCAGAAGAAAGCCACCATGGGGCAGTTACAGAACAAG
  GAGAACAATAACACCAAGGACAGCCCTAGTAGGCAGTGCTCCTGGGACAAGTCTGAGTCACCCCAGAGA
  AGCAGCATGAACAATGGATCCCCCACAGCTCTATCAGGCAGCAAAACCAACAGCCCAAAGAACAGTGTT
  CACAAGCTAGATGTGTCTAGAAGCCCCCCTCTCATGGTCAAAAAGAACCCAGCCTTTAATAAGGGTAGT
  GGGATAGTTACCAATGGGTCCTTCAGCAGCAGTAATGCAGAAGGTCTTGAGAAAACCCAAACCACCCCC
  AATGGGAGCCTACAGGCCAGAAGGAGCTCTTCACTGAAGGTATCTGGTACCAAAATGGGCACGCACAGT
  GTACAGAATGGAACGGTGCGCATGGGCATTTTGAACAGCGACACACTCGGGAACCCCACAAATGTTCGA
  AACATGAGCTGGCTGCCAAATGGCTATGTGACCCTGAGGGATAACAAGCAGAAAGAACAAGCTGGAGAG
  TTAGGCCAGCACAACAGACTGTCCACCTATGATAATGTCCATCAACAGTTCTCCATGATGAACCTTGAT
  GACAAGCAGAGCATTGACAGTGCTACCTGGTCCACTTCCTCCTGTGAAATCTCCCTCCCTGAGAACTCC
  AACTCCTGTCGCTCTTCTACCACCACCTGCCCAGAGCAAGACTTTTTTGGGGGGAACTTTGAGGACCCT
  GTTTTGGATGGGCCCCCGCAGGACGACCTTTCCCACCCCAGGGACTATGAAAGCAAAAGTGACCACAGG
  AGTGTGGGAGGTCGAAGTAGTCGTGCCACCAGTAGCAGTGACAACAGTGAGACATTTGTGGGCAACAGC
  AGCAGCAACCACAGTGCACTGCACAGTTTAGTTTCCAGCCTGAAACAGGAAATGACCAAACAGAAGATA
  GAGTATGAGTCCAGGATAAAGAGCTTAGAACAGCGAAACTTGACTTTGGAAACAGAAATGATGAGCCTC
  CATGATGAACTGGATCAGGAGAGGAAAAAGTTCACAATGATAGAAATAAAAATGCGAAATGCCGAGCGA
  GCAAAAGAAGATGCCGAGAAAAGAAATGACATGCTACAGAAAGAAATGGAGCAGTTTTTTTCCACGTTT
  GGAGAACTGACAGTGGAACCCAGGAGAACCGAGAGAGGAAACACAATATGGATTCAG
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG239254
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MFVQGGDRDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPM
  LVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVI
  PYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVF
  GPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNK
  ENNNTKDSPSRQCSWDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGS
  GIVTNGSFSSSNAEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVR
  NMSWLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENS
  NSCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNS
  SSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAER
  AKEDAEKRNDMLQKEMEQFFSTFGELTVEPRRTERGNTIWIQ
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001287805
• ORF Size: 1989 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001287805.2
• RefSeq Size: 4010 bp
• RefSeq ORF: 1992 bp
• Locus ID: 83478
• Cytogenetics: 4q21.23-q21.3
• MW: 74.9 kDa
• Gene Summary: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]