ABCB7 (NM_001271699) Human Tagged ORF Clone
CAT#: RG239385
- TrueORF®
ABCB7 (GFP-tagged) - Human ATP-binding cassette, sub-family B (MDR/TAP), member 7 (ABCB7), transcript variant 5
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Specifications
Product Data | |
Tag | TurboGFP |
Symbol | ABCB7 |
Synonyms | ABC7; ASAT; Atm1p; EST140535 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG239385 representing NM_001271699.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGCTGCTCGCGATGCATTCTTGGCGCTGGGCGGCCGCGGCGGCTGCTTTCGAAAAGCGCCGGCAC TCCGCGATTCTGATCCGGCCTTTAGTCTCTGTTAGCGGCTCAGGTCCGCAGTGGAGGCCACATCAACTC GGCGCCTTGGGAACCGCTCGAGCCTACCAGCAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGA TTGGGAAAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAA AAGAGGACATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGGCCATGAAT ATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAAC CTGAGTGATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGA GCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGA AGAATAGCCAAAAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACG GGAGCTTTATCTAAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTT AATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAG TTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGA ACTAGATTTAGAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTG AATTATGAAACTGTGAAGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAG ACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATT TTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTT GGAGATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTA TATAGAGAGACTAGACAAGCACTCATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAA ATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAAT GTGCATTTTGAATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAG AAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTAT GAGCCTCAAAAGGGTAGCATTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGG AGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATAT GGAAACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATT CTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAG CAAAGAGTAGCAATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCA TCGTTAGATTCGATTACTGAAGAGACTATTCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCT ATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAG GTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCAT ACACAGAGCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAA GAGGAGGAAAGAAAGAAACTACAAGAAGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239385
Blue=ORF Red=Cloning site Green=Tag(s) MALLAMHSWRWAAAAAAFEKRRHSAILIRPLVSVSGSGPQWRPHQLGALGTARAYQQIPESLKSITWQR LGKGNSGQFLDAAKALQVWPLIEKRTCWHGHAGGGLHTDPKEGAMNIVVPFMFKYAVDSLNQMSGNMLN LSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQT GALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWR TRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAI FSVGLTAIMVLASQGIVAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQ IKDKVMASPLQITPQTATVAFDNVHFEYIEGQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFY EPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAI LRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKHRTS IFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSRVQNHDNPKWEAKKENISK EEERKKLQEEIVNSVKGCGNCSC TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001271699 |
ORF Size | 2139 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reference Data | |
RefSeq | NM_001271699.3 |
RefSeq Size | 2408 bp |
RefSeq ORF | 2142 bp |
Locus ID | 22 |
Cytogenetics | Xq13.3 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | ABC transporters |
MW | 78.7 kDa |
Gene Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012] |
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