ADCY7 (NM_001286057) Human Tagged ORF Clone

CAT#: RG239444

ADCY7 (GFP-tagged) - Human adenylate cyclase 7 (ADCY7), transcript variant 2

Specifications

Product Data

• Tag: TurboGFP
• Symbol: ADCY7
• Synonyms: AC7
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG239444 representing NM_001286057.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGCCAGCCAAGGGGCGCTACTTCCTCAACGAGGGCGAGGAGGGCCCTGACCAAGATGCGCTCTACGAG
  AAGTACCAGCTCACCAGCCAGCATGGGCCGCTGCTGCTCACGCTCCTGCTGGTGGCCGCCACTGCCTGC
  GTGGCCCTCATCATCATTGCCTTCAGCCAGGGGGACCCCTCCAGACACCAGGCCATTCTGGGCATGGCG
  TTCCTGGTGCTGGCGGTGTTTGCGGCCCTCTCTGTGCTGATGTACGTCGAGTGTCTCCTGCGGCGCTGG
  CTCAGGGCCTTGGCGCTGCTCACCTGGGCCTGCTTGGTGGCGCTGGGCTATGTGCTGGTGTTCGACGCA
  TGGACAAAGGCGGCCTGTGCGTGGGAGCAGGTGCCCTTCTTCCTGTTCATTGTCTTCGTGGTGTACACA
  CTACTGCCCTTCAGCATGCGGGGCGCTGTCGCCGTTGGGGCCGTCTCCACTGCCTCCCACCTCCTGGTG
  CTCGGTTCTTTGATGGGAGGCTTCACGACACCCAGTGTCCGGGTGGGGCTGCAGCTGCTGGCCAACGCA
  GTCATCTTCCTGTGTGGGAACCTGACAGGCGCCTTCCACAAGCACCAAATGCAGGATGCGTCCCGGGAC
  CTCTTCACCTACACTGTGAAGTGCATCCAGATCCGCCGGAAGCTGCGCATCGAGAAGCGCCAGCAGGAG
  AACCTGCTGCTGTCAGTGCTTCCGGCCCACATCTCCATGGGCATGAAGCTGGCCATCATCGAACGGCTC
  AAGGAGCATGGTGACCGTCGCTGCATGCCTGACAACAACTTCCACAGCCTCTACGTCAAGAGGCACCAG
  AATGTCAGCATCCTCTATGCGGACATCGTGGGCTTCACGCAGCTGGCCAGCGACTGTTCTCCCAAGGAG
  CTGGTGGTGGTGCTGAATGAGCTCTTTGGCAAGTTCGACCAGATCGCCAAGGCCAACGAGTGCATGCGA
  ATCAAGATCCTCGGCGACTGCTACTACTGTGTATCGGGCCTGCCCGTGTCGCTGCCTACCCACGCCCGG
  AACTGCGTGAAGATGGGGCTGGACATGTGCCAGGCCATCAAGCAGGTGCGGGAGGCCACGGGCGTGGAC
  ATCAACATGCGTGTGGGCATACACTCGGGGAATGTGCTGTGCGGGGTCATCGGGCTGCGCAAGTGGCAG
  TATGACGTGTGGTCCCACGACGTGTCCCTGGCCAACCGGATGGAGGCAGCCGGAGTACCCGGCCGGGTG
  CACATCACGGAGGCCACGCTAAAGCACCTGGACAAGGCGTACGAGGTGGAGGATGGGCACGGGCAGCAG
  CGGGACCCCTACCTCAAGGAGATGAACATCCGCACCTACCTGGTCATCGACCCCCGGAGCCAGCAGCCA
  CCCCCGCCCAGCCAACACCTCCCCAGGCCCAAGGGGGACGCGGCCCTGAAGATGCGGGCGTCAGTGCGC
  ATGACCCGGTACCTCGAGTCCTGGGGGGCGGCACGGCCCTTTGCACATCTCAACCACCGTGAGAGCGTG
  AGCAGTGGTGAGACCCACGTCCCCAACGGGCGGAGGCCTAAGAGCGTTCCCCAGCGCCACCGCCGGACC
  CCAGACAGAAGCATGTCCCCCAAGGGGCGGTCGGAGGATGACTCGTACGATGACGAGATGCTGTCAGCC
  ATTGAGGGGCTCAGCTCCACGAGGCCCTGCTGCTCCAAGTCCGATGACTTCTACACCTTTGGGTCCATC
  TTCCTGGAGAAGGGCTTTGAGCGCGAGTACCGCCTGGCACCCATCCCCCGGGCCCGCCACGACTTTGCC
  TGCGCCAGCCTGATCTTCGTCTGCATCCTGCTCGTCCATGTCCTGCTCATGCCCAGGACGGCGGCACTG
  GGTGTGTCCTTCGGGCTGGTGGCCTGTGTACTGGGGCTGGTGCTGGGCCTGTGCTTTGCCACCAAGTTC
  TCGAGGTGCTGCCCAGCTCGGGGGACGCTCTGCACTATCTCTGAGAGGGTGGAGACACAGCCCCTGCTG
  AGGCTGACCCTGGCCGTCCTGACCATCGGCAGCCTGCTCACTGTGGCCATCATCAACCTGCCCCTGATG
  CCTTTCCAAGTTCCAGAGCTGCCTGTTGGCAATGAGACAGGCCTACTGGCCGCGAGCAGCAAGACAAGA
  GCCCTGTGTGAGCCCCTCCCGCACCTGCATACTGTTTTTTCCCGTTTAAATGAGCTCACTTCA
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG239444
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MPAKGRYFLNEGEEGPDQDALYEKYQLTSQHGPLLLTLLLVAATACVALIIIAFSQGDPSRHQAILGMA
  FLVLAVFAALSVLMYVECLLRRWLRALALLTWACLVALGYVLVFDAWTKAACAWEQVPFFLFIVFVVYT
  LLPFSMRGAVAVGAVSTASHLLVLGSLMGGFTTPSVRVGLQLLANAVIFLCGNLTGAFHKHQMQDASRD
  LFTYTVKCIQIRRKLRIEKRQQENLLLSVLPAHISMGMKLAIIERLKEHGDRRCMPDNNFHSLYVKRHQ
  NVSILYADIVGFTQLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHAR
  NCVKMGLDMCQAIKQVREATGVDINMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRV
  HITEATLKHLDKAYEVEDGHGQQRDPYLKEMNIRTYLVIDPRSQQPPPPSQHLPRPKGDAALKMRASVR
  MTRYLESWGAARPFAHLNHRESVSSGETHVPNGRRPKSVPQRHRRTPDRSMSPKGRSEDDSYDDEMLSA
  IEGLSSTRPCCSKSDDFYTFGSIFLEKGFEREYRLAPIPRARHDFACASLIFVCILLVHVLLMPRTAAL
  GVSFGLVACVLGLVLGLCFATKFSRCCPARGTLCTISERVETQPLLRLTLAVLTIGSLLTVAIINLPLM
  PFQVPELPVGNETGLLAASSKTRALCEPLPHLHTVFSRLNELTS
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001286057
• ORF Size: 2202 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001286057.1, NP_001272986.1
• RefSeq Size: 2582 bp
• RefSeq ORF: 2205 bp
• Locus ID: 113
• Cytogenetics: 16q12.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Calcium signaling pathway, Chemokine signaling pathway, Dilated cardiomyopathy, Gap junction, GnRH signaling pathway, Melanogenesis, Oocyte meiosis, Progesterone-mediated oocyte maturation, Purine metabolism, Vascular smooth muscle contraction
• MW: 81.9 kDa
• Gene Summary: 'This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013]'