AMOTL2 (NM_001278685) Human Tagged ORF Clone

CAT#: RG239542

AMOTL2 (GFP-tagged) - Human angiomotin like 2 (AMOTL2), transcript variant 3

Specifications

Product Data

• Tag: TurboGFP
• Symbol: AMOTL2
• Synonyms: LCCP
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG239542 representing NM_001278685.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGAGGACACTGGAAGACTCCTCGGGGACAGTCCTGCACCGCCTCATCCAGGAGCAGCTGCGCTACGGC
  AACCTGACTGAGACGCGCACGCTGCTAGCCATCCAGCAGCAGGCCCTGAGGGGTGGGGCTGGAACTGGG
  GGTACAGGGAGCCCCCAGGCCTCCCTGGAGATCCTGGCCCCAGAGGACAGTCAGGTGCTGCAGCAGGCC
  ACCAGGCAGGAGCCCCAGGGCCAGGAGCACCAGGGCGGTGAGAACCACCTGGCAGAGAACACCCTCTAC
  CGGCTATGCCCACAGCCCAGCAAGGGAGAGGAGCTGCCCACCTATGAGGAGGCCAAAGCCCACTCGCAG
  TACTATGCGGCCCAGCAGGCAGGGACCCGGCCACATGCGGGGGACCGAGATCCCCGTGGGGCCCCGGGA
  GGCAGTCGGAGGCAGGACGAGGCCCTGCGGGAGCTGAGGCATGGGCACGTGCGCTCGTTGAGTGAACGG
  CTCCTTCAGTTGTCCCTGGAGAGGAACGGCGCCCGGGCCCCCAGCCACATGAGCTCCTCCCACAGCTTC
  CCACAGCTGGCCCGCAACCAGCAGGGCCCCCCACTGAGGGGCCCCCCTGCTGAGGGCCCAGAGTCCCGA
  GGACCCCCACCTCAGTACCCTCATGTTGTACTAGCTCATGAGACCACCACTGCTGTCACTGACCCACGG
  TACCGTGCCCGCGGCAGCCCGCACTTCCAGCATGCTGAAGTCAGGATCCTGCAGGCCCAGGTGCCTCCT
  GTGTTCCTCCAACAGCAGCAGCAGTACCAGTACCTGCAGCAATCTCAGGAGCACCCCCCTCCCCCACAT
  CCAGCTGCTCTCGGCCATGGCCCCCTGAGCTCCCTCAGTCCACCTGCTGTGGAGGGGCCAGTGAGTGCC
  CAGGCCTCCTCAGCCACCTCGGGCAGTGCCCACCTGGCCCAGATGGAGGCCGTGCTGAGGGAGAATGCC
  AGGCTGCAGAGAGACAATGAGCGGCTGCAGAGGGAGCTGGAGAGCTCTGCGGAGAAGGCTGGCCGCATT
  GAGAAGCTGGAAAGCGAAATCCAGCGGCTCTCTGAGGCCCATGAGAGCCTGACCAGAGCCTCCTCCAAG
  CGTGAGGCCCTGGAGAAGACCATGCGGAACAAGATGGACAGTGAAATGAGGAGGCTGCAAGACTTCAAC
  CGGGATCTTAGAGAGAGATTGGAATCTGCAAATCGCCGCCTGGCAAGCAAGACACAGGAGGCCCAGGCC
  GGCAGTCAGGACATGGTGGCCAAGCTGCTTGCTCAGAGCTACGAACAGCAGCAGGAGCAAGAGAAGCTG
  GAGCGAGAGATGGCACTGCTGCGCGGCGCCATCGAGGACCAGCGGCGGCGTGCCGAGCTGCTGGAGCAG
  GCTCTGGGCAATGCGCAGGGCCGGGCAGCTCGAGCCGAAGAGGAGCTGCGCAAGAAGCAGGCCTATGTG
  GAGAAAGTGGAGCGGCTGCAGCAGGCGCTCGGGCAGCTGCAGGCAGCCTGTGAGAAGCGGGAGCAGCTG
  GAGCTGCGTCTGCGGACTCGCCTGGAGCAGGAACTCAAGGCCCTGCGTGCACAGCAGGCAGGTGCCCCA
  GGTGGTAGCAGTGGCAGTGGTGGGTCTCCAGAGCTCAGCGCCCTGCGACTGTCAGAACAACTGCGAGAG
  AAGGAGGAGCAGATCCTGGCGCTGGAGGCCGACATGACCAAGTGGGAGCAGAAGTATTTGGAGGAACGT
  GCCATGAGGCAGTTTGCCATGGATGCGGCTGCCACGGCTGCTGCTCAGCGTGACACCACTCTCATCCGA
  CATTCCCCCCAGCCCTCACCCAGCAGCAGCTTCAATGAGGGTCTGCTCACTGGTGGCCACAGGCATCAG
  GAGATGGAAAGCAGGTTAAAGGTGCTCCATGCCCAGATCCTGGAGAAGGATGCAGTGATCAAGGTCCTT
  CAGCAGCGCTCCAGGAGAGACCCTGGCAAGGCCATCCAGGGCTCCCTGCGGCCTGCCAAGTCGGTGCCA
  TCTGTTTTCGCGGCTGCGGCAGCAGGAACCCAGGGCTGGCAAGGGCTCTCTTCTAGTGAGCGACAAACA
  GCAGACGCCCCTGCTCGGCTGACTACAGACAGAGCACCCACAGAGGAGCCAGTGGTCACAGCTCCCCCT
  GCTGCCCATGCCAAACACGGGAGCAGAGATGGGAGCACCCAGACTGAGGGCCCCCCAGACAGCACCTCC
  ACCTGCCTGCCACCGGAGCCTGACAGCCTTCTGGGGTGCAGCAGTAGCCAGAGAGCAGCCTCTCTGGAC
  TCTGTAGCTACATCCAGAGTCCAGGACTTGTCAGACATGGTGGAGATACTGATC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG239542
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MRTLEDSSGTVLHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGTGGTGSPQASLEILAPEDSQVLQQA
  TRQEPQGQEHQGGENHLAENTLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGTRPHAGDRDPRGAPG
  GSRRQDEALRELRHGHVRSLSERLLQLSLERNGARAPSHMSSSHSFPQLARNQQGPPLRGPPAEGPESR
  GPPPQYPHVVLAHETTTAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLQQQQQYQYLQQSQEHPPPPH
  PAALGHGPLSSLSPPAVEGPVSAQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRI
  EKLESEIQRLSEAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQA
  GSQDMVAKLLAQSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYV
  EKVERLQQALGQLQAACEKREQLELRLRTRLEQELKALRAQQAGAPGGSSGSGGSPELSALRLSEQLRE
  KEEQILALEADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQ
  EMESRLKVLHAQILEKDAVIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFAAAAAGTQGWQGLSSSERQT
  ADAPARLTTDRAPTEEPVVTAPPAAHAKHGSRDGSTQTEGPPDSTSTCLPPEPDSLLGCSSSQRAASLD
  SVATSRVQDLSDMVEILI
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001278685
• ORF Size: 2331 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001278685.2
• RefSeq Size: 4999 bp
• RefSeq ORF: 2334 bp
• Locus ID: 51421
• Cytogenetics: 3q22.2
• MW: 85.9 kDa
• Gene Summary: Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]