AMOTL2 (NM_001278683) Human Tagged ORF Clone

CAT#: RG239657

AMOTL2 (GFP-tagged) - Human angiomotin like 2 (AMOTL2), transcript variant 1

Specifications

Product Data

• Tag: TurboGFP
• Symbol: AMOTL2
• Synonyms: LCCP
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG239657 representing NM_001278683.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGACTGGGCGAAAAGCCAGCGGTGGCACACCTTGCACTCTGCGTAAAGGGGCGCCTATTATCACCTTG
  GGGAAGAACTGGACAGAGCGCCTGGCGGCGGGTGATTCAGTTGGGTGCTCTGGGGCCAGGTGCCACCGG
  CCATTGTCCAGGCAGCTGTGTGCAAGCCAAAGAAGCATGAGGACACTGGAAGACTCCTCGGGGACAGTC
  CTGCACCGCCTCATCCAGGAGCAGCTGCGCTACGGCAACCTGACTGAGACGCGCACGCTGCTAGCCATC
  CAGCAGCAGGCCCTGAGGGGTGGGGCTGGAACTGGGGGTACAGGGAGCCCCCAGGCCTCCCTGGAGATC
  CTGGCCCCAGAGGACAGTCAGGTGCTGCAGCAGGCCACCAGGCAGGAGCCCCAGGGCCAGGAGCACCAG
  GGCGGTGAGAACCACCTGGCAGAGAACACCCTCTACCGGCTATGCCCACAGCCCAGCAAGGGAGAGGAG
  CTGCCCACCTATGAGGAGGCCAAAGCCCACTCGCAGTACTATGCGGCCCAGCAGGCAGGGACCCGGCCA
  CATGCGGGGGACCGAGATCCCCGTGGGGCCCCGGGAGGCAGTCGGAGGCAGGACGAGGCCCTGCGGGAG
  CTGAGGCATGGGCACGTGCGCTCGTTGAGTGAACGGCTCCTTCAGTTGTCCCTGGAGAGGAACGGCGCC
  CGGGCCCCCAGCCACATGAGCTCCTCCCACAGCTTCCCACAGCTGGCCCGCAACCAGCAGGGCCCCCCA
  CTGAGGGGCCCCCCTGCTGAGGGCCCAGAGTCCCGAGGACCCCCACCTCAGTACCCTCATGTTGTACTA
  GCTCATGAGACCACCACTGCTGTCACTGACCCACGGTACCGTGCCCGCGGCAGCCCGCACTTCCAGCAT
  GCTGAAGTCAGGATCCTGCAGGCCCAGGTGCCTCCTGTGTTCCTCCAACAGCAGCAGCAGTACCAGTAC
  CTGCAGCAATCTCAGGAGCACCCCCCTCCCCCACATCCAGCTGCTCTCGGCCATGGCCCCCTGAGCTCC
  CTCAGTCCACCTGCTGTGGAGGGGCCAGTGAGTGCCCAGGCCTCCTCAGCCACCTCGGGCAGTGCCCAC
  CTGGCCCAGATGGAGGCCGTGCTGAGGGAGAATGCCAGGCTGCAGAGAGACAATGAGCGGCTGCAGAGG
  GAGCTGGAGAGCTCTGCGGAGAAGGCTGGCCGCATTGAGAAGCTGGAAAGCGAAATCCAGCGGCTCTCT
  GAGGCCCATGAGAGCCTGACCAGAGCCTCCTCCAAGCGTGAGGCCCTGGAGAAGACCATGCGGAACAAG
  ATGGACAGTGAAATGAGGAGGCTGCAAGACTTCAACCGGGATCTTAGAGAGAGATTGGAATCTGCAAAT
  CGCCGCCTGGCAAGCAAGACACAGGAGGCCCAGGCCGGCAGTCAGGACATGGTGGCCAAGCTGCTTGCT
  CAGAGCTACGAACAGCAGCAGGAGCAAGAGAAGCTGGAGCGAGAGATGGCACTGCTGCGCGGCGCCATC
  GAGGACCAGCGGCGGCGTGCCGAGCTGCTGGAGCAGGCTCTGGGCAATGCGCAGGGCCGGGCAGCTCGA
  GCCGAAGAGGAGCTGCGCAAGAAGCAGGCCTATGTGGAGAAAGTGGAGCGGCTGCAGCAGGCGCTCGGG
  CAGCTGCAGGCAGCCTGTGAGAAGCGGGAGCAGCTGGAGCTGCGTCTGCGGACTCGCCTGGAGCAGGAA
  CTCAAGGCCCTGCGTGCACAGCAGAGACAGGCAGGTGCCCCAGGTGGTAGCAGTGGCAGTGGTGGGTCT
  CCAGAGCTCAGCGCCCTGCGACTGTCAGAACAACTGCGAGAGAAGGAGGAGCAGATCCTGGCGCTGGAG
  GCCGACATGACCAAGTGGGAGCAGAAGTATTTGGAGGAACGTGCCATGAGGCAGTTTGCCATGGATGCG
  GCTGCCACGGCTGCTGCTCAGCGTGACACCACTCTCATCCGACATTCCCCCCAGCCCTCACCCAGCAGC
  AGCTTCAATGAGGGTCTGCTCACTGGTGGCCACAGGCATCAGGAGATGGAAAGCAGGTTAAAGGTGCTC
  CATGCCCAGATCCTGGAGAAGGATGCAGTGATCAAGGTCCTTCAGCAGCGCTCCAGGAGAGACCCTGGC
  AAGGCCATCCAGGGCTCCCTGCGGCCTGCCAAGTCGGTGCCATCTGTTTTCGCGGCTGCGGCAGCAGGA
  ACCCAGGGCTGGCAAGGGCTCTCTTCTAGTGAGCGACAAACAGCAGACGCCCCTGCTCGGCTGACTACA
  GACAGAGCACCCACAGAGGAGCCAGTGGTCACAGCTCCCCCTGCTGCCCATGCCAAACACGGGAGCAGA
  GATGGGAGCACCCAGACTGAGGGCCCCCCAGACAGCACCTCCACCTGCCTGCCACCGGAGCCTGACAGC
  CTTCTGGGGTGCAGCAGTAGCCAGAGAGCAGCCTCTCTGGACTCTGTAGCTACATCCAGAGTCCAGGAC
  TTGTCAGACATGGTGGAGATACTGATC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG239657
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MTGRKASGGTPCTLRKGAPIITLGKNWTERLAAGDSVGCSGARCHRPLSRQLCASQRSMRTLEDSSGTV
  LHRLIQEQLRYGNLTETRTLLAIQQQALRGGAGTGGTGSPQASLEILAPEDSQVLQQATRQEPQGQEHQ
  GGENHLAENTLYRLCPQPSKGEELPTYEEAKAHSQYYAAQQAGTRPHAGDRDPRGAPGGSRRQDEALRE
  LRHGHVRSLSERLLQLSLERNGARAPSHMSSSHSFPQLARNQQGPPLRGPPAEGPESRGPPPQYPHVVL
  AHETTTAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLQQQQQYQYLQQSQEHPPPPHPAALGHGPLSS
  LSPPAVEGPVSAQASSATSGSAHLAQMEAVLRENARLQRDNERLQRELESSAEKAGRIEKLESEIQRLS
  EAHESLTRASSKREALEKTMRNKMDSEMRRLQDFNRDLRERLESANRRLASKTQEAQAGSQDMVAKLLA
  QSYEQQQEQEKLEREMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALG
  QLQAACEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQILALE
  ADMTKWEQKYLEERAMRQFAMDAAATAAAQRDTTLIRHSPQPSPSSSFNEGLLTGGHRHQEMESRLKVL
  HAQILEKDAVIKVLQQRSRRDPGKAIQGSLRPAKSVPSVFAAAAAGTQGWQGLSSSERQTADAPARLTT
  DRAPTEEPVVTAPPAAHAKHGSRDGSTQTEGPPDSTSTCLPPEPDSLLGCSSSQRAASLDSVATSRVQD
  LSDMVEILI
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001278683
• ORF Size: 2511 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001278683.1, NP_001265612.1
• RefSeq Size: 4991 bp
• RefSeq ORF: 2514 bp
• Locus ID: 51421
• Cytogenetics: 3q22.2
• MW: 92.3 kDa
• Gene Summary: Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]