LPHN2 (ADGRL2) (NM_001297705) Human Tagged ORF Clone

CAT#: RG240025

LPHN2 (GFP-tagged) - Human latrophilin 2 (LPHN2), transcript variant 3

Specifications

Product Data

• Tag: TurboGFP
• Symbol: ADGRL2
• Synonyms: CIRL2; CL2; LEC1; LPHH1; LPHN2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG240025 representing NM_001297705.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGTGTCTTCTGGTTGCAGAATGCGAAGTCTGTGGTTTATCATTGTAATCAGCTTCTTACCAAATACA
  GAAGGTTTCAGCAGAGCAGCTTTACCATTTGGGCTGGTGAGGCGAGAATTATCCTGTGAAGGTTATTCT
  ATAGATCTGCGATGCCCGGGCAGTGATGTCATCATGATTGAGAGCGCTAACTATGGTCGGACGGATGAC
  AAGATTTGTGATGCTGACCCATTTCAGATGGAGAATACAGACTGCTACCTCCCCGATGCCTTCAAAATT
  ATGACTCAAAGGTGCAACAATCGAACACAGTGTATAGTAGTTACTGGGTCAGATGTGTTTCCTGATCCA
  TGTCCTGGAACATACAAATACCTTGAAGTCCAATATGAATGTGTCCCTTACATTTTTGTGTGTCCTGGG
  ACCTTGAAAGCAATTGTGGACTCACCATGTATATATGAAGCTGAACAAAAGGCGGGTGCTTGGTGCAAG
  GACCCTCTTCAGGCTGCAGATAAAATTTATTTCATGCCCTGGACTCCCTATCGTACCGATACTTTAATA
  GAATATGCTTCTTTAGAAGATTTCCAAAATAGTCGCCAAACAACAACATATAAACTTCCAAATCGAGTA
  GATGGTACTGGATTTGTGGTGTATGATGGTGCTGTCTTCTTTAACAAAGAAAGAACGAGGAATATTGTG
  AAATTTGACTTGAGGACTAGAATTAAGAGTGGCGAGGCCATAATTAACTATGCCAACTACCATGATACC
  TCACCATACAGATGGGGAGGAAAGACTGATATCGACCTAGCAGTTGATGAAAATGGTTTATGGGTCATT
  TACGCCACTGAACAGAACAATGGAATGATAGTTATTAGCCAGCTGAATCCATACACTCTTCGATTTGAA
  GCAACGTGGGAGACTGTATACGACAAACGTGCCGCATCAAATGCTTTTATGATATGCGGAGTCCTCTAT
  GTGGTTAGGTCAGTTTATCAAGACAATGAAAGTGAAACAGGCAAGAACTCAATTGATTACATTTATAAT
  ACCCGATTAAACCGAGGAGAATATGTAGATGTTCCCTTCCCCAACCAGTATCAGTATATTGCTGCAGTG
  GATTACAATCCAAGAGATAACCAACTTTACGTGTGGAACAATAACTTCATTTTACGATATTCTCTGGAG
  TTTGGTCCACCTGATCCTGCCCAAGTGCCTACCACAGCTGTGACAATAACTTCTTCAGCTGAGCTGTTC
  AAAACCATAATATCAACCACAAGCACTACTTCACAGAAAGGCCCCATGAGCACAACTGTAGCTGGATCA
  CAGGAAGGAAGCAAAGGGACAAAACCACCTCCAGCAGTTTCTACAACCAAAATTCCACCTATAACAAAT
  ATTTTTCCCCTGCCAGAGAGATTCTGTGAAGCATTAGACTCCAAGGGGATAAAGTGGCCTCAGACACAA
  AGGGGAATGATGGTTGAACGACCATGCCCTAAGGGAACAAGAGGAACTGCCTCATATCTCTGCATGATT
  TCCACTGGAACATGGAACCCTAAGGGCCCCGATCTTAGCAACTGTACCTCACACTGGGTGAATCAGCTG
  GCTCAGAAGATCAGAAGCGGAGAAAATGCTGCTAGTCTTGCCAATGAACTGGCTAAACATACCAAAGGG
  CCAGTGTTTGCTGGGGATGTAAGTTCTTCAGTGAGATTGATGGAGCAGTTGGTGGACATCCTTGATGCA
  CAGCTGCAGGAACTGAAACCTAGTGAAAAAGATTCAGCTGGACGGAGTTATAACAAGGCAATTGTTGAC
  ACAGTGGACAACCTTCTGAGACCCGAAGCTTTGGAATCATGGAAACATATGAATTCTTCTGAACAAGCA
  CATACTGCAACAATGTTACTCGATACATTGGAAGAAGGAGCTTTTGTCCTAGCTGACAATCTTTTAGAA
  CCAACAAGGGTCTCAATGCCCACAGAAAATATTGTCCTGGAAGTTGCCGTACTCAGTACAGAAGGACAG
  ATCCAAGACTTTAAATTTCCTCTGGGCATCAAAGGAGCAGGCAGCTCAATCCAACTGTCCGCAAATACC
  GTCAAACAGAACAGCAGGAATGGGCTTGCAAAGTTGGTGTTCATCATTTACCGGAGCCTGGGACAGTTC
  CTTAGTACAGAAAATGCAACCATTAAACTGGGTGCTGATTTTATTGGTCGTAATAGCACCATTGCAGTG
  AACTCTCACGTCATTTCAGTTTCAATCAATAAAGAGTCCAGCCGAGTATACCTGACTGATCCTGTGCTT
  TTTACCCTGCCACACATTGATCCTGACAATTATTTCAATGCAAACTGCTCCTTCTGGAACTACTCAGAG
  AGAACTATGATGGGATATTGGTCTACCCAGGGCTGCAAGCTGGTTGACACTAATAAAACTCGAACAACG
  TGTGCATGCAGCCACCTAACCAATTTTGCAATTCTCATGGCCCACAGGGAAATTGCATATAAAGATGGC
  GTTCATGAATTACTTCTTACAGTCATCACCTGGGTGGGAATTGTCATTTCCCTTGTTTGCCTGGCTATC
  TGCATCTTCACCTTCTGCTTTTTCCGTGGCCTACAGAGTGACCGAAATACTATTCACAAGAACCTTTGT
  ATCAACCTTTTCATTGCTGAATTTATTTTCCTAATAGGCATTGATAAGACAAAATATGCGATTGCATGC
  CCAATATTTGCAGGACTTCTACACTTTTTCTTTTTGGCAGCTTTTGCTTGGATGTGCCTAGAAGGTGTG
  CAGCTCTACCTAATGTTAGTTGAAGTTTTTGAAAGTGAATATTCAAGGAAAAAATATTACTATGTTGCT
  GGTTACTTGTTTCCTGCCACAGTGGTTGGAGTTTCAGCTGCTATTGACTATAAGAGCTATGGAACAGAA
  AAAGCTTGCTGGCTTCATGTTGATAACTACTTTATATGGAGCTTCATTGGACCTGTTACCTTCATTATT
  CTGCTAAATATTATCTTCTTGGTGATCACATTGTGCAAAATGGTGAAGCATTCAAACACTTTGAAACCA
  GATTCTAGCAGGTTGGAAAACATTAAGTCTTGGGTGCTTGGCGCTTTCGCTCTTCTGTGTCTTCTTGGC
  CTCACCTGGTCCTTTGGGTTGCTTTTTATTAATGAGGAGACTATTGTGATGGCATATCTCTTCACTATA
  TTTAATGCTTTCCAGGGAGTGTTCATTTTCATCTTTCACTGTGCTCTCCAAAAGAAAGTACGAAAAGAA
  TATGGCAAGTGCTTCAGACACTCATACTGCTGTGGAGGCCTCCCAACTGAGAGTCCCCACAGTTCAGTG
  AAGGCATCAACCACCAGAACCAGTGCTCGCTATTCCTCTGGCACACAGAGTCGTATAAGAAGAATGTGG
  AATGATACTGTGAGAAAACAATCAGAATCTTCTTTTATCTCAGGTGACATCAATAGCACTTCAACACTT
  AATCAAGGACTGACATCACATGGTCTGAGAGCCCATCTTCAAGATTTATATCATTTAGAGCTACTCTTA
  GGCCAGATAGCC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG240025
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MVSSGCRMRSLWFIIVISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDD
  KICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYIFVCPG
  TLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRV
  DGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVI
  YATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNSIDYIYN
  TRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELF
  KTIISTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVSTTKIPPITNIFPLPERFCEALDSKGIKWPQTQ
  RGMMVERPCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKG
  PVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKAIVDTVDNLLRPEALESWKHMNSSEQA
  HTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKGAGSSIQLSANT
  VKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVL
  FTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG
  VHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIAC
  PIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTE
  KACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLG
  LTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRHSYCCGGLPTESPHSSV
  KASTTRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGLTSHGLRAHLQDLYHLELLL
  GQIA
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001297705
• ORF Size: 3531 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001297705.2
• RefSeq Size: 6127 bp
• RefSeq ORF: 3534 bp
• Locus ID: 23266
• Cytogenetics: 1p31.1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• MW: 132.7 kDa
• Gene Summary: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]