MYT1L (NM_001303052) Human Tagged ORF Clone

CAT#: RG240033

MYT1L (GFP-tagged) - Human myelin transcription factor 1-like (MYT1L), transcript variant 1

Specifications

Product Data

• Tag: TurboGFP
• Symbol: MYT1L
• Synonyms: MRD39; myT1-L; NZF1; ZC2H2C2; ZC2HC4B
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG240033 representing NM_001303052.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGAGGTGGACACCGAGGAGAAGCGGCATCGCACGCGGTCCAAAGGGGTTCGAGTTCCCGTGGAACCA
  GCCATACAAGAGCTGTTCAGCTGTCCCACCCCTGGCTGTGACGGCAGTGGTCATGTCAGTGGCAAATAT
  GCAAGACACAGAAGTGTATATGGTTGTCCCTTGGCGAAAAAAAGAAAAACACAAGATAAACAGCCCCAG
  GAACCTGCTCCTAAACGAAAGCCATTTGCCGTGAAAGCAGACAGCTCCTCAGTGGATGAGTGTGACGAC
  AGTGATGGGACTGAGGACATGGATGAGAAGGAGGAGGATGAGGGGGAGGAGTACTCCGAGGACAATGAT
  GAGCCAGGGGATGAGGACGAGGAGGACGAGGAGGGGGACCGGGAGGAGGAGGAGGAGATCGAGGAGGAG
  GATGAGGACGATGACGAGGATGGAGAAGATGTGGAGGATGAAGAAGAGGAAGAGGAGGAGGAGGAGGAG
  GAGGAAGAGGAAGAAGAAAACGAAGACCATCAAATGAATTGTCACAATACTCGAATAATGCAAGACACA
  GAAAAGGATGATAACAATAATGACGAATATGACAATTACGATGAACTGGTGGCCAAGTCATTGTTAAAC
  CTCGGCAAAATCGCTGAGGATGCAGCCTACCGGGCCAGGACTGAGTCAGAAATGAACAGCAATACCTCC
  AATAGTCTGGAAGACGATAGTGACAAAAACGAAAACCTGGGTCGGAAAAGTGAGTTGAGTTTAGACTTA
  GACAGTGATGTTGTTAGAGAAACAGTGGACTCCCTTAAACTATTAGCCCAAGGACACGGTGTTGTGCTC
  TCAGAAAACATGAATGACAGAAATTATGCAGACAGCATGTCGCAGCAAGACAGTAGAAATATGAATTAC
  GTCATGTTGGGGAAGCCCATGAACAACGGACTCATGGAAAAGATGGTGGAGGAGAGCGATGAGGAGGTG
  TGTCTGAGCAGTCTGGAGTGTTTGAGGAATCAGTGCTTCGACCTGGCCAGGAAGCTCAGTGAGACCAAC
  CCGCAGGAGAGGAATCCGCAGCAGAACATGAACATCCGTCAGCATGTCCGGCCAGAAGAGGACTTCCCC
  GGAAGGACGCCGGACAGAAACTACTCGGACATGCTGAACCTCATGCGGCTGGAGGAGCAGTTGAGCCCC
  CGGTCGAGAGTGTTTGCCAGCTGTGCGAAGGAGGATGGGTGTCATGAGCGGGACGACGATACCACCTCT
  GTGAACTCGGACAGGTCTGAAGAGGTGTTCGACATGACCAAGGGGAACCTGACCCTGCTGGAGAAAGCC
  ATCGCTTTGGAAACGGAAAGAGCAAAGGCCATGAGGGAGAAGATGGCCATGGAAGCTGGGAGGAGGGAC
  AATATGAGGTCATATGAGGACCAGTCTCCGAGACAACTTCCCGGGGAGGACAGAAAGCCTAAATCCAGT
  GACAGCCATGTCAAAAAGCCATACTATGGTAAAGATCCCTCAAGAACAGAAAAGAAAGAGAGCAAGTGT
  CCAACCCCCGGGTGTGATGGAACCGGCCACGTAACTGGGCTGTACCCACATCACCGCAGCCTGTCCGGA
  TGCCCGCACAAAGATAGGGTCCCTCCAGAAATCCTTGCCATGCATGAAAGTGTCCTCAAGTGCCCCACT
  CCGGGCTGCACGGGGCGCGGGCATGTCAACAGCAACAGGAACTCCCACCGAAGCCTCTCCGGATGCCCG
  ATCGCTGCAGCAGAGAAACTGGCCAAGGCACAGGAAAAGCACCAGAGCTGCGACGTGTCCAAGTCCAGC
  CAGGCCTCGGACCGCGTGCTCAGGCCAATGTGCTTTGTGAAGCAGCTGGAGATTCCTCAGTATGGCTAC
  AGAAACAATGTCCCCACAACTACGCCGCGTTCCAACCTGGCCAAGGAGCTCGAGAAATATTCCAAGACC
  TCGTTTGAATACAACAGTTACGACAACCATACTTATGGCAAGCGAGCCATAGCTCCCAAGGTGCAAACC
  AGGGATATATCCCCCAAAGGATATGATGATGCGAAGCGGTACTGCAAGGACCCCAGCCCCAGCAGCAGC
  AGCACCAGCAGCTACGCGCCCAGCAGCAGCAGCAACCTGAGCTGCGGCGGGGGCAGCAGCGCCAGCAGC
  ACGTGCAGCAAGAGCAGCTTCGACTACACGCACGACATGGAGGCGGCCCACATGGCGGCCACCGCCATC
  CTCAACCTGTCCACGCGCTGCCGCGAGATGCCGCAGAACCTGAGCACCAAGCCGCAGGACCTGTGCGCC
  ACGCGGAACCCTGACATGGAGGTGGATGAGAACGGGACCCTGGACCTCAGCATGAACAAGCAGAGGCCG
  CGGGACAGCTGCTGCCCCATCCTGACCCCTCTGGAGCCCATGTCCCCCCAGCAGCAGGCAGTGATGAAC
  AACCGGTGTTTCCAGCTGGGCGAGGGCGACTGCTGGGACTTGCCCGTAGACTACACCAAAATGAAACCC
  CGGAGGATAGACGAGGACGAGTCCAAAGACATTACTCCAGAAGACTTGGACCCATTCCAGGAGGCTCTA
  GAAGAAAGACGGTATCCCGGGGAGGTGACCATCCCAAGTCCCAAACCCAAGTACCCTCAGTGCAAGGAG
  AGCAAAAAGGACTTAATAACTCTGTCTGGCTGCCCCCTGGCGGACAAAAGCATTCGAAGTATGCTGGCC
  ACCAGCTCCCAAGAACTCAAGTGCCCCACGCCTGGCTGTGATGGTTCTGGACATATCACCGGCAATTAT
  GCTTCTCATCGGAGCCTTTCAGGTTGCCCAAGAGCAAAGAAAAGTGGTATCAGGATAGCACAGAGCAAA
  GAAGATAAAGAAGATCAAGAACCCATCAGGTGTCCGGTCCCCGGGTGCGACGGCCAGGGCCACATCACT
  GGGAAGTACGCGTCCCATCGCAGCGCCTCCGGGTGCCCCTTGGCGGCCAAGAGGCAGAAAGACGGGTAC
  CTGAATGGCTCCCAGTTCTCCTGGAAGTCGGTCAAGACGGAAGGCATGTCCTGCCCCACGCCAGGATGC
  GACGGCTCAGGCCACGTCAGCGGCAGCTTCCTCACACACCGCAGCTTGTCAGGATGCCCGAGAGCCACG
  TCAGCGATGAAGAAGGCAAAGCTTTCTGGAGAGCAGATGCTGACCATCAAACAGCGGGCCAGCAACGGT
  ATAGAAAATGATGAAGAAATCAAACAGTTAGATGAAGAAATCAAGGAGCTAAATGAATCCAATTCCCAG
  ATGGAAGCCGATATGATTAAACTCAGAACTCAGATTACCACGATGGAGAGCAACCTGAAGACCATCGAA
  GAGGAGAACAAAGTGATTGAGCAGCAGAACGAGTCTCTCCTCCACGAGCTGGCGAACCTGAGCCAGTCT
  CTGATCCACAGCCTGGCTAACATCCAGCTGCCGCACATGGATCCAATCAATGAACAAAATTTTGATGCT
  TACGTGACTACTTTGACGGAAATGTATACAAATCAAGATCGTTATCAGAGTCCAGAAAATAAAGCCCTA
  CTGGAAAATATAAAGCAGGCTGTGAGAGGAATTCAGGTC
  ACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG240033
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQ
  EPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE
  DEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLN
  LGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVL
  SENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETN
  PQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTS
  VNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKSS
  DSHVKKPYYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHESVLKCPT
  PGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGY
  RNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSS
  STSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCA
  TRNPDMEVDENGTLDLSMNKQRPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKP
  RRIDEDESKDITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLA
  TSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHIT
  GKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRAT
  SAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQITTMESNLKTIE
  EENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKAL
  LENIKQAVRGIQV
  TRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHVMG
  YGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPEDSV
  IFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFAFR
  RVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-NotI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001303052
• ORF Size: 3558 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data

• RefSeq: NM_001303052.2
• RefSeq Size: 7198 bp
• RefSeq ORF: 3561 bp
• Locus ID: 23040
• Cytogenetics: 2p25.3
• Protein Families: Transcription Factors
• MW: 133.5 kDa
• Gene Summary: This gene encodes a member of the zinc finger superfamily of transcription factors whose expression, thus far, has been found only in neuronal tissues. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with an autosomal dominant form of cognitive disability and with autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Jul 2017]