Mrvi1 (NM_001105211) Rat Tagged ORF Clone

CAT#: RR200093

Mrvi1 (Myc-DDK-tagged ORF) - Rat MRV integration site 1 homolog (mouse) (Mrvi1), transcript variant 1, (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Mrvi1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR200093 representing NM_001105211
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCAAAACCAAACAGCTGATTTGTGGCTCTTGGATCCTGGAAAGGGAACCCAGCTTGGAACAGGGATGG
  GAAGGAGTTTGACTTGTCCTTTTGGCGTCTCCCCAGCCTGCGGAGCCCAAGCCTCTTGGAGCATCTTTGG
  GGTTGTCACAGCAGAGGTTCCAGGCACGCACAGCCACTCCAACCAGGCGGCTGCCATGCCCCACATTCCT
  GAGGATGAGGAGCCCCCCGGAGAGCCACAGGCAGCCCAGACCCAAGACTCTCCCTCTGCAGGACCGTTTT
  GCAGCCCTCCCACAATCATCCTGACGGGGGATGCCAGTTCACCTGGAGGAGAGACTGACACAAATCTGGT
  CAAGAGGGCTCCCAGCCCCCACCGCAGGCTTTCCCACCGACACCTGAAGGTCTCCACTGCCTCGCTGACT
  TCTGTGGACCCCTTGGGGCACGTCATTGACCTGGTAAATGACCAGCTGCCGGACATCAGCATCTCAGAAG
  AGGACAAGAAGAAAAACCTGGCACTTCTAGAAGAAGCCAAGTTGGTTAGCGAGCGGTTCCTGACCCGCCG
  CGGGAGGAGATCAAGGAGCAGCCTCGGAGACGCCCCATCAGCTGTTTCTCCAAACCTCAGCTCTGGAGCT
  TCTCCTGCATCCTCTAGGAGTTGCTCGTTCACCATCTCCACACCACCAGGTTTTGACACATGCAGTGGCC
  CACAGTCCCCTCTGCCGGGATCACCAGCACAGCAAAAGGGACATGAGGATGATGTCTTCTCGTCTCACCT
  CGGAGAGCCTAATGCCTCCAAAGGGCTAGCTGACCGGAAGCAGAATGACCAGAGGAAAGTGTCTCAAGGC
  AGACTGGCTCCTCGCTCTCCCACAGTGGAGAAATCCAAAGAACTTTCAGTAGAACAAAAGGAAAACTTCG
  ATCCCCTTCAGCATCTGGAGGCCACACCCATGGCTCAGACCTCTGGAGCAAGCGTCAGTGGGAAAATGGC
  GCTGAACAGTCCCCAGCCTGGCCCTGCGGAGATGGAGCTGGGGAGGCAGCTTCTGAAGACAGCCAGGGAA
  GACAACCCTCTGCCCAGAACCACAGTCCAGGGCTCAGGAGGAACGGCCTCCCCACATTCTCAGGGACAGG
  GCTCTGCTGGAGAGCTTATGGGGCCCAAGGCTGGCTCCAAGGCTGAGCCGAGGCCTCCTGTGTCCCGGCC
  CCCTCTGATTCGGGGGGTCTCCTGGGACAGCAGCCCTGAAGAACCTGGTCCCCTGCTGCAAAAGGTGCTC
  GCTAAGCTGCCTCTGGCAGAGGAAGAAAAGCGGTTTCCAGGCAAAGCCAAGCCAGCCAAGCCACCGGGGC
  TCAAAGACTTCCAGATACAAGTACAGCCGGTGCGCATGCAGAAGCTGACCAAGCTTCGGGAGGAACACAT
  CCTGATGAGAAACCAGAACCTGGTGGGGTTCAAGCTCCCTGAACTGAGTGAAGCTGCAGAGCAAGACAAA
  GGAGTCTCATCTGAGCTTGCCCCAGCAGCTGAGGAAGAAGAATCAAAGAGTGGTCTGGATGTGATGCCCA
  ACATTTCTGACATATTGCTACGTAAACTTAGGGTTCACAAGTCACTCACTGGAAGCGCCCCTCCGCTCAC
  AGAAAAGGAAGTCGAGAACGTGTTTGTACAACTGTCCTTGGCCTTTAGAAATGACAGCTACACCTTGGAG
  TCTAGGATTAACCAGGCTGAAAGGGAACGCAACTTGACGGAAGAGAACACCGAGAAGGAACTGGAAAACT
  TCAAAGCCTCTATTACGTCCTCAGCATCCATCTGGTACCACTGCGAGCACCGGGAGACCTACCAGAAGCT
  TCTGGAAGACATCGCAGTCTTGCATCGTCTGGCTGCACGCCTCTCCAGCCGGGCTGAAGTGGTGGGTGCT
  GTGCGCCAGGAAAAGCGCATGTCAAAGGCCACGGAAGTGATGATGCAGTATGTGGAGAATCTGAAGAGAA
  CGTACGAGAAGGACCATGCTGAGCTCATGGAATTTAAGAAACTCGCAAATCAGAATTCTAGTCGCAGCTG
  TGGGCCCTCTGAAGACGGGGTTCCTCGCACGGCGCGATCTATGTCCCTCACGATGGGAAAGAACATGCCC
  CGTCGGAGGGTCAGCGTTGCTGTGGTTCCCAAGTTTAATGCCCTGAACCTGCCTGGCCAAGCCCCCAGCT
  CATCACCCATGCCCTCTCTCCCAGCTCTGTCTGAATCGACCAACGGGAGAAGCAGCATCTCCACCTCTCC
  AGTGCTGCCTGCACTTTTGGAAAATGGAAAGACAAATGCAGAGGCTAACTGTGAAGTGTGCGCCCCTGTG
  CCACTCCCAAGCTACCCGGAGGAGACGAGCCAAGAGGCCAAGGCCAGAGCAGAGGAAGAAGCCTACAACA
  AAGGATACCAGGAAGGGGTAAAGAAGACCGAAGAACTTCAAGACCTGAAGGAGGAGGAAGAGGAACAGAA
  GGCAGAGAGTCCTCAGGAACCAGAAGAGGTCGAAGAAACCCAGGAAGACGAGAAGGACCAGAGAAGCAGC
  AAACTTGAAGAACTGGTCCACTTCCTACAAGTCATGTATCCCAAATTGTGTCAACACTGGCAAGTGATCT
  GGATGATGGCCGCTGTGATGCTGGTCTTGAGTGTTGTGCTTGGGCTCTACAGTTCCTATAACTCCTGCAC
  GGAGCAGGCCGACGGGCCCCCTGGGAGATCCACCTGCTCTGCAGCCCAGCGGGACTCCTGGTGGAGCTCG
  GGACTCCAGCAAGAGCTGCCAGCAGAGCAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR200093 representing NM_001105211
  Red=Cloning site Green=Tags(s)
  
  MQNQTADLWLLDPGKGTQLGTGMGRSLTCPFGVSPACGAQASWSIFGVVTAEVPGTHSHSNQAAAMPHIP
  EDEEPPGEPQAAQTQDSPSAGPFCSPPTIILTGDASSPGGETDTNLVKRAPSPHRRLSHRHLKVSTASLT
  SVDPLGHVIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRRSRSSLGDAPSAVSPNLSSGA
  SPASSRSCSFTISTPPGFDTCSGPQSPLPGSPAQQKGHEDDVFSSHLGEPNASKGLADRKQNDQRKVSQG
  RLAPRSPTVEKSKELSVEQKENFDPLQHLEATPMAQTSGASVSGKMALNSPQPGPAEMELGRQLLKTARE
  DNPLPRTTVQGSGGTASPHSQGQGSAGELMGPKAGSKAEPRPPVSRPPLIRGVSWDSSPEEPGPLLQKVL
  AKLPLAEEEKRFPGKAKPAKPPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGFKLPELSEAAEQDK
  GVSSELAPAAEEEESKSGLDVMPNISDILLRKLRVHKSLTGSAPPLTEKEVENVFVQLSLAFRNDSYTLE
  SRINQAERERNLTEENTEKELENFKASITSSASIWYHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGA
  VRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTMGKNMP
  RRRVSVAVVPKFNALNLPGQAPSSSPMPSLPALSESTNGRSSISTSPVLPALLENGKTNAEANCEVCAPV
  PLPSYPEETSQEAKARAEEEAYNKGYQEGVKKTEELQDLKEEEEEQKAESPQEPEEVEETQEDEKDQRSS
  KLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLSVVLGLYSSYNSCTEQADGPPGRSTCSAAQRDSWWSS
  GLQQELPAEQ
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001105211
• ORF Size: 2760 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001105211.1, NP_001098681.1
• RefSeq Size: 5935
• RefSeq ORF: 2763
• Locus ID: 308899
• MW: 100.2 kDa
• Gene Summary: This gene is similar to a putative mouse tumor suppressor gene that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. Studies in mouse suggest that MRV integration at the homologous mouse gene induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]