Tp63 (NM_001127342) Rat Tagged ORF Clone

CAT#: RR200159

Tp63 (Myc-DDK-tagged ORF) - Rat tumor protein p73-like (Tp73l), transcript variant 4, (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Tp63
• Synonyms: Ket; P73l; Tp73l; Trp63
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR200159 representing NM_001127342
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTGTACCTGGAAAGCAATGCCCAGACTCAATTTAGTGAGCCACAGTACACGAACCTGGGGCTCCTGA
  ACGGCATGGACCAGCAGATTCAGAACGGCTCCTCATCTACCAGCCCCTATAACACAGACCATGCACAGAA
  CAGCGTGACGGCACCCTCGCCCTATGCACAGCCCAGCTCAACCTTCGATGCCCTTTCTCCATCCCCTGCC
  ATTCCCTCCAACACAGATTACCCAGGCCCACACAGCTTCGATGTGTCCTTCCAGCAGTCAAGCACCGCCA
  AGTCAGCTACCTGGACGTATTCCACCGAACTGAAGAAACTCTACTGCCAGATTGCAAAGACCTGCCCCAT
  CCAGATCAAGGTGATGACCCCACCCCCACAGGGCGCCGTCATTCGTGCCATGCCTGTCTACAAGAAAGCC
  GAGCATGTCACCGAGGTTGTGAAACGATGTCCTAACCACGAGCTGAGCCGCGAGTTCAATGAGGGACAGA
  TTGCCCCTCCCAGTCATCTGATTCGAGTAGAAGGGAACAGCCATGCCCAGTATGTAGAAGATCCTATCAC
  AGGAAGGCAGAGCGTGCTGGTCCCTTATGAGCCACCACAGGTTGGCACTGAATTCACAACAGTCCTGTAC
  AATTTCATGTGCAACAGCAGCTGTGTCGGAGGAATGAACCGCCGTCCAATTTTAATCATCGTTACTCTGG
  AAACCAGAGATGGGCAAGTCCTGGGCCGACGTTGCTTTGAGGCCCGGATCTGCGCTTGCCCAGGAAGAGA
  CCGGAAGGCCGATGAAGACAGCATCAGAAAGCAGCAAGTATCAGACAGCGCAAAGAACGGCGATGGTACG
  AAGCGCCCTTTCCGTCAGAATACCCACGGAATCCAGATGACTTCCATCAAGAAACGGAGATCCCCAGATG
  ATGAGCTGCTGTACCTACCAGTGAGAGGCCGTGAGACTTATGAAATGCTGCTCAAGATCAAGGAGTCGCT
  CGAGCTCATGCAGTATCTCCCTCAGCACACGATCGAGACGTACAGGCAGCAGCAGCAGCAGCAGCACCAA
  CACCTACTTCAGAAACAGACCTCGATGCAGTCTCAGTCTTCATACGGTAACAGCTCACCACCTCTGAACA
  AAATGAACAGCATGAACAAGCTGCCGTCTGTGAGCCAGCTTATCAACCCACAGCAGCGCAACGCCCTGAC
  TCCCACCACCATGCCTGAGGGCATGGGAGCCAACATTCCTATGATGGGCACTCACATGCCAATGGCTGGA
  GACATGAATGGACTCAGCCCCACCCAAGCTCTTCCTCCTCCACTCTCCATGCCCTCCACCTCCCACTGCA
  CCCCCCCACCTCCGTACCCAACAGACTGCAGCATTGTCAGTTTCTTAGCAAGGTTGGGCTGTTCATCATG
  TCTGGACTATTTCACGACCCAGGGGCTGACCACCATCTATCAGATTGAGCATTACTCCATGGATGATTTG
  GCAAGTCTGAAGATCCCTGAGCAGTTCCGACATGCCATCTGGAAGGGGATCCTGGACCACAGGCAGCTGC
  ATGACTTCTCCTCACCTCCGCATCTCCTGAGAACCCCCAGTGGTGCCTCTACAGTCAGTGTGGGCTCCAG
  TGAGACCCGTGGAGAACGTGTGATTGATGCCGTGCGCTTTACTCTCCGCCAGACCATCTCTTTCCCACCC
  CGTGATGAGTGGAACGATTTCAACTTTGACATGGATTCCCGTCGCAACAAGCAGCAGCGCATCAAAGAGG
  AAGGAGAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR200159 representing NM_001127342
  Red=Cloning site Green=Tags(s)
  
  MLYLESNAQTQFSEPQYTNLGLLNGMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPA
  IPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKA
  EHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLY
  NFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGT
  KRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQ
  HLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMGANIPMMGTHMPMAG
  DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDL
  ASLKIPEQFRHAIWKGILDHRQLHDFSSPPHLLRTPSGASTVSVGSSETRGERVIDAVRFTLRQTISFPP
  RDEWNDFNFDMDSRRNKQQRIKEEGE
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001127342
• ORF Size: 1758 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001127342.1, NP_001120814.1
• RefSeq Size: 4562
• RefSeq ORF: 1761
• Locus ID: 246334
• MW: 65.7 kDa
• Gene Summary: This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Both alternative splicing and the use of alternative promoters result in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2009]