Vegfa (NM_001110334) Rat Tagged ORF Clone
CAT#: RR200264
- TrueORF®
Vegfa (Myc-DDK-tagged ORF) - Rat vascular endothelial growth factor A (Vegfa), transcript variant 3, (10 ug)
"NM_001110334" in other vectors (3)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Vegfa |
Synonyms | Vegf; VEGF-A; VEGF111; VEGF164; VPF |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RR200264 representing NM_001110334
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC CTGACGGACAGACAGACAGACACCGCCCCCAGCCCCAGCGCCCACCTCCTCGCCGGCGGGCAGCCGACGG TGGACGCGGCGGCGAGCCGCGAGCAGGAGCCGAAGCCCGCGCCCGGAGGCGGGGTGGAGGGGGTCGGGGC TCGCGGGATTGCACGGAAACTTTTCGTCCAACTTCTGGGCTCTTCTCTCTCCGGAGTAGCCGTGGTCTGC GCCGCAGGAGGCAAACCGATCGGAGCTGGGAGAAGTGCTAGCTCGGGCCTGGAGAAGCCGGGGCCCGAGA AGAGAGGGGAGAAAGAGAAGGAAGAGGAGAGGGGGCCGCAGTGGGCGCTCGGCTCTCGGGAGCCGGGCTC ATGGACGGGTGAGGCGGCGGTGTGCGCAGACAGTGCTCCAGCCGCGCGCGCGCCCCAGGCCCCGGCCCGG GCCTCGGTTCCAGAAGGGAGAGGAGCCCGCCAAGGCGCGCAAGAGAGCGGGCTGCCTCGCAGTCCGAGCC GGAGAGGGAGCGCGAGCCGCGCCGGCCCCGGACGGGCCTCTGAAACCATGAACTTTCTGCTCTCTTGGGT GCACTGGACCCTGGCTTTACTGCTGTACCTCCACCATGCCAAGTGGTCCCAGGCTGCACCCACGACAGAA GGGGAGCAGAAAGCCCATGAAGTGGTGAAGTTCATGGACGTCTACCAGCGCAGCTATTGCCGTCCAATTG AGACCCTGGTGGACATCTTCCAGGAGTACCCCGATGAGATAGAGTATATCTTCAAGCCGTCCTGTGTGCC CCTAATGCGGTGTGCGGGCTGCTGCAATGATGAAGCCCTGGAGTGCGTGCCCACGTCGGAGAGCAACGTC ACTATGCAGATCATGCGGATCAAACCTCACCAAAGCCAGCACATAGGAGAGATGAGCTTCCTGCAGCATA GCAGATGTGAATGCAGACCAAAGAAAGATAGAACAAAGCCAGAAAAATGTGACAAGCCAAGGCGG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RR200264 representing NM_001110334
Red=Cloning site Green=Tags(s) LTDRQTDTAPSPSAHLLAGGQPTVDAAASREQEPKPAPGGGVEGVGARGIARKLFVQLLGSSLSGVAVVC AAGGKPIGAGRSASSGLEKPGPEKRGEKEKEEERGPQWALGSREPGSWTGEAAVCADSAPAARAPQAPAR ASVPEGRGARQGAQESGLPRSPSRRGSASRAGPGRASETMNFLLSWVHWTLALLLYLHHAKWSQAAPTTE GEQKAHEVVKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNV TMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKCDKPRR TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001110334 |
ORF Size | 975 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001110334.1, NM_001110334.2, NP_001103804.1 |
RefSeq Size | 3342 |
RefSeq ORF | 978 |
Locus ID | 83785 |
MW | 35 kDa |
Gene Summary | This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RN200264 | Vegfa (untagged ORF) - Rat vascular endothelial growth factor A (Vegfa), transcript variant 3, (10 ug) |
USD 420.00 |
|
RR200264L3 | Lenti ORF clone of Vegfa (Myc-DDK-tagged ORF) - Rat vascular endothelial growth factor A (Vegfa), transcript variant 3, (10 ug) |
USD 640.00 |
|
RR200264L4 | Lenti ORF clone of Vegfa (mGFP-tagged ORF) - Rat vascular endothelial growth factor A (Vegfa), transcript variant 3, (10 ug) |
USD 700.00 |
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