Gnas (NM_019132) Rat Tagged ORF Clone
CAT#: RR200465L3
- LentiORF®
Lenti ORF clone of Gnas (Myc-DDK-tagged ORF) - Rat GNAS complex locus (Gnas), transcript variant 3, (10 ug)
"NM_019132" in other vectors (3)
Product Images
Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Gnas |
Synonyms | ALEX; G-alpha-8; Gnas1; Gnpas; Nesp55; SCG6 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR200465).
|
Restriction Sites | SgfI-RsrII Cloning Scheme for this gene |
ACCN | NM_019132 |
ORF Size | 1182 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_019132.1, NP_062005.1 |
RefSeq Size | 1738 |
RefSeq ORF | 1185 |
Locus ID | 24896 |
Gene Summary | This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants have been found for this gene. [provided by RefSeq, Apr 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RN200465 | Gnas (untagged ORF) - Rat GNAS complex locus (Gnas), transcript variant 3, (10 ug) |
USD 420.00 |
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RR200465 | Gnas (Myc-DDK-tagged ORF) - Rat GNAS complex locus (Gnas), transcript variant 3, (10 ug) |
USD 420.00 |
|
RR200465L4 | Lenti ORF clone of Gnas (mGFP-tagged ORF) - Rat GNAS complex locus (Gnas), transcript variant 3, (10 ug) |
USD 700.00 |
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