Ptgs1 (NM_017043) Rat Tagged ORF Clone

CAT#: RR200711

Ptgs1 (Myc-DDK-tagged ORF) - Rat prostaglandin-endoperoxide synthase 1 (Ptgs1), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Ptgs1
• Synonyms: Cox-1; Cox-3; Cox1; Cox3; Pghs-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR200711 representing NM_017043
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTCGAAGGAGTCTCTCGCTCCAGTTTCCCCTGCTGCTGCTCCTGCTGCTGCTCCCACCACCCCCGG
  TACTGCTCACAGATGCTGGGGTACCCTCACCAGTCAATCCCTGTTGTTACTATCCATGCCAGAACCAGGG
  TGTCTGTGTCCGCTTCGGCCTCGACCACTACCAATGTGACTGTACTCGCACGGGCTACTCGGGCCCCAAC
  TGTACTATCCCTGAGATCTGGACCTGGCTTCGGAGTTCCCTGCGGCCCAGCCCCTCATTCACCCATTTCC
  TGCTGACACACGGGTACTGGATCTGGGAGTTTGTGAATGCCACCTTCATCCGAGAAGTACTCATGCGCCT
  GGTACTCACGGTGCGGTCCAACCTTATCCCCAGCCCTCCAACCTACAACACAGCACATGACTACATCAGC
  TGGGAGTCCTTCTCCAACGTGAGCTACTATACTCGCATTCTGCCCTCTGTACCCAAAGACTGTCCCACAC
  CCATGGGAACCAAAGGGAAGAAGCAGTTACCAGATATTCATCTTCTGGCCCAACGATTGCTGCTGAGAAG
  GGAGTTCATTCCCGCCCCGCAGGGGACCAACGTCTTGTTTGCTTTCTTTGCACAACACTTCACCCACCAG
  TTCTTCAAGACCTCTGGAAAGATGGGTCCTGGCTTTACCAAGGCCTTAGGCCATGGGGTAGACCTTGGCC
  ACATTTATGGAGATAGTCTGGAACGACAGTACCACCTGCGGCTCTTCAAGGATGGGAAACTTAAGTACCA
  GGTGCTGGATGGAGAGGTGTACCCACCTTCCGTAGAACAGGCGTCCGTGTTGATGCGCTACCCACCAGGT
  GTCCCGCCCGAAAAGCAGATGGCTGTGGGCCAGGAGGTGTTTGGGTTGCTCCCGGGTCTGATGCTCTTCT
  CCACGATCTGGCTGCGCGAGCATAACCGTGTGTGTGACTTGCTGAAGGAGGAGCATCCTACATGGGATGA
  CGAGCAGCTCTTCCAGACCACTCGCCTCATCCTTATAGGGGAAACCATCAAGATTATCATCGAGGAGTAC
  GTACAGCACTTGAGTGGCTATTTCCTGCAGCTCAAGTTTGACCCGGAGCTGCTGTTCCGAGCCCAGTTCC
  AGTATCGCAACCGCATCGCCTTGGAATTCAACCACCTCTATCACTGGCATCCGCTCATGCCTGATTCCTT
  CCAAGTGGGCTCACAAGAGTACAGCTATGAGCAGTTTTTATTTAACACATCTATGCTGGTGGACTACGGT
  GTCGAGGCACTGGTGGATGCCTTCTCTCGCCAGAGGGCTGGCCGGATTGGTGGGGGTAGGAACTTTGACT
  ACCATGTTCTGCATGTGGCCGAGGATGTCATCAAGGAGTCCCGAGAAATGCGCCTGCAGTCCTTCAATGA
  ATACCGAAAGAGGTTTGGCCTGAAGCCTTACACTTCTTTCCAGGAGTTCACAGGAGAGAAGGAGATGGCC
  GCTGAGTTGGAGGAGCTATATGGTGACATCGATGCTTTAGAGTTCTACCCGGGGCTGATGCTGGAGAAGT
  GCCAGCCCAACTCCCTCTTTGGGGAGAGCATGATAGAGATGGGGGCTCCTTTCTCCCTCAAGGGCCTCCT
  AGGGAATCCCATCTGTTCCCCAGAGTACTGGAAACCCAGCACATTCGGTGGTGATGTGGGTTTCAACATC
  GTTAACACAGCCTCACTGAAGAAACTGGTCTGCCTCAACACCAAGACCTGCCCCTATGTCTCCTTCCGTG
  TGCCAGATTACCCTGGAGATGACGGGTCTGTCTTCGTGAGACCTTCCACTGAGCTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR200711 representing NM_017043
  Red=Cloning site Green=Tags(s)
  
  MSRRSLSLQFPLLLLLLLLPPPPVLLTDAGVPSPVNPCCYYPCQNQGVCVRFGLDHYQCDCTRTGYSGPN
  CTIPEIWTWLRSSLRPSPSFTHFLLTHGYWIWEFVNATFIREVLMRLVLTVRSNLIPSPPTYNTAHDYIS
  WESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDIHLLAQRLLLRREFIPAPQGTNVLFAFFAQHFTHQ
  FFKTSGKMGPGFTKALGHGVDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPPSVEQASVLMRYPPG
  VPPEKQMAVGQEVFGLLPGLMLFSTIWLREHNRVCDLLKEEHPTWDDEQLFQTTRLILIGETIKIIIEEY
  VQHLSGYFLQLKFDPELLFRAQFQYRNRIALEFNHLYHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYG
  VEALVDAFSRQRAGRIGGGRNFDYHVLHVAEDVIKESREMRLQSFNEYRKRFGLKPYTSFQEFTGEKEMA
  AELEELYGDIDALEFYPGLMLEKCQPNSLFGESMIEMGAPFSLKGLLGNPICSPEYWKPSTFGGDVGFNI
  VNTASLKKLVCLNTKTCPYVSFRVPDYPGDDGSVFVRPSTEL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_017043
• ORF Size: 1806 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017043.4, NP_058739.4
• RefSeq Size: 2811
• RefSeq ORF: 1809
• Locus ID: 24693
• MW: 69 kDa
• Gene Summary: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. [provided by RefSeq, Jan 2014]