Cd74 (NM_013069) Rat Tagged ORF Clone

CAT#: RR205378

Cd74 (Myc-DDK-tagged ORF) - Rat Cd74 molecule, major histocompatibility complex, class II invariant chain (Cd74), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Cd74
• Synonyms: INVG34
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR205378 representing NM_013069
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGATGACCAGCGCGACCTCATCTCTAACCATGAGCAGCTGCCCATCCTGGGCCAGCGTGCTAGAGCCC
  CAGAAAGCAATTGCAACCGTGGAGTCCTGTACACCAGTGTCTCTGTCCTGGTGGCTCTGCTCTTGGCTGG
  GCAGGCCACCACTGCTTACTTCCTGTACCAGCAGCAGGGCCGCCTGGACAAGCTGACCGTCACCTCCCAG
  AACCTGCAACTGGAGAACCTTCGCATGAAGCTTCCGAAATCTGCCAAACCTGTGAGCCCGATGCGCATGG
  CTACTCCCTTGCTGATGCGCCCACTGTCCATGGATAACATGCTCCAAGCGCCCGTGAAGAATGTTACCAA
  GTATGGCAACATGACCCAGGACCACGTGATGCACCTGCTTACGAAGTCTGGACCCGTGAACTACCCACAG
  CTGAAGGGGAGCTTCCCGGAGAATCTGAAGCACCTTAAGAACTCTATGAATGGTCTGGACTGGAAGGTCT
  TTGAGAGCTGGATGAAACAGTGGCTGTTGTTTGAAATGAGCAAGAACTCCCTGGAGGAGAAGCAGCCCAC
  CCAGACTCCACCTAAAGAGCCACTGGACATGGAAGACCCATCTTCTGGCCTGGGAGTGACCAAGCAGGAT
  ATGGGCCAAATGTTCTTG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR205378 representing NM_013069
  Red=Cloning site Green=Tags(s)
  
  MDDQRDLISNHEQLPILGQRARAPESNCNRGVLYTSVSVLVALLLAGQATTAYFLYQQQGRLDKLTVTSQ
  NLQLENLRMKLPKSAKPVSPMRMATPLLMRPLSMDNMLQAPVKNVTKYGNMTQDHVMHLLTKSGPVNYPQ
  LKGSFPENLKHLKNSMNGLDWKVFESWMKQWLLFEMSKNSLEEKQPTQTPPKEPLDMEDPSSGLGVTKQD
  MGQMFL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_013069
• ORF Size: 648 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013069.1, NM_013069.2, NP_037201.1
• RefSeq Size: 1220
• RefSeq ORF: 651
• Locus ID: 25599
• MW: 24.5 kDa
• Gene Summary: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. [UniProtKB/Swiss-Prot Function]