Kmt5c (NM_001107475) Rat Tagged ORF Clone

CAT#: RR205798

Suv420h2 (Myc-DDK-tagged ORF) - Rat suppressor of variegation 4-20 homolog 2 (Drosophila) (Suv420h2), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Kmt5c
• Synonyms: Suv420h2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR205798 representing NM_001107475
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGGCCTGACCGAGTGACAGCCCGAGAACTGTGCGAGAATGATGACCTGGCCACCAGCCTTGTTCTTG
  ACCCCTACCTCGGCTTCCGCACCCATAAGATGAATGTCAGCCCTGTGCCCACCCTCCGACGACAACACCA
  CCTTCGCTCAGCACTGGAAGCTTTCCTAAGGCAACGGGACCTGGAAGCTGCATTCCGGGCCCTGACACTG
  GGAGGCTGGATGGCCCACTACTTTCAGAACCGTGCTCCTCGGCAGGAGGCTGCCCTCAAGAACCACATTT
  TTTGCTACCTCCGCGCCTTCCTGCCTGAGAGTGGCTTCACCATTCTGCCCTGCACCCGCTACTCCATGGA
  GACCAATGGGGCCAAGATTGTGTCTACCCGTGCTTGGAAGAAGAATGAGAAGCTGGAGCTGCTGGTGGGC
  TGCATTGCAGAGCTGCGGGAAGAGGATGAATACCTACTTAGGGCAGGCGAGAACGACTTCAGCGTCATGT
  ACTCCACTCGAAAAAGGAGTGCCCAGCTGTGGCTTGGCCCAGCTGCCTTTATCAACCATGACTGCAAACC
  CAACTGCAAGTTTGTGCCCTCAGATGGAAATACTGCCTGTGTGAAGGTGCTACGGGACATTGAGCCGGGG
  GATGAAGTAACTTGCTTCTATGGCGAGGGCTTCTTCGGTGAGAAGAATGAGCACTGTGAATGCTATACCT
  GTGAGAGGAAAGGCGAGGGAGCTTTCAGACTTCAGCCCAGGGAGCCGGAGCTGAGGCCACGGCCCCTGGA
  CAAGTATGAGCTCCGAGAGACAAAGAGGCGTCTGCAGCAGTGTTTGGACAGCAGCCAGCAGAACCTGCTG
  AGCCTGCGGGCCTGCTCCCACCTGTCCCCACTGCGCCCTGACCCATTCTGTGCTGCCTGCCAGCCCTCAT
  GCCTGCTGCCTGTCAGTCCCCACATGGACTACTTGCCCCTCTGGCTCCAGTGGGTGCCTCAGCCCCAGCC
  CAGAGTACGTCCCCGGAAGCGCCGCCGTCGCCGCCGCCGTCGCCCCAGGATACCCCAGGCTTCATTGTCC
  CCTGACCTGCACACTGCCTGTGTATCCCTACACCGATGGGGAGGCTGTGGTCCCCACTGCCAACTACGGG
  CTGAGGCCATGGTGACCCTACACCTGCTCCCCCAGACTCGCTGGACCCCAAAACAGGACTGGTACTGGGC
  CCGACGCTATGGGCTACCTTCTGTGGTGCGCGTTGAACTTTCCCCTCTAGCCCCAGCCCTACCAGCTGCT
  CCTGCTCCTGCTGGGAACCTAGGTCCCACCCCCACCCCTGACCTCATACCTAAACAGGCCCTTGCCTTCG
  CTCCTTTCTGCCCACCTAAGCGCCTCCGGCTAGTGGTCAGCCATGGTTCTATTGATCTGGACATCAATAG
  TGGTGAGCCA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR205798 representing NM_001107475
  Red=Cloning site Green=Tags(s)
  
  MGPDRVTARELCENDDLATSLVLDPYLGFRTHKMNVSPVPTLRRQHHLRSALEAFLRQRDLEAAFRALTL
  GGWMAHYFQNRAPRQEAALKNHIFCYLRAFLPESGFTILPCTRYSMETNGAKIVSTRAWKKNEKLELLVG
  CIAELREEDEYLLRAGENDFSVMYSTRKRSAQLWLGPAAFINHDCKPNCKFVPSDGNTACVKVLRDIEPG
  DEVTCFYGEGFFGEKNEHCECYTCERKGEGAFRLQPREPELRPRPLDKYELRETKRRLQQCLDSSQQNLL
  SLRACSHLSPLRPDPFCAACQPSCLLPVSPHMDYLPLWLQWVPQPQPRVRPRKRRRRRRRRPRIPQASLS
  PDLHTACVSLHRWGGCGPHCQLRAEAMVTLHLLPQTRWTPKQDWYWARRYGLPSVVRVELSPLAPALPAA
  PAPAGNLGPTPTPDLIPKQALAFAPFCPPKRLRLVVSHGSIDLDINSGEP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001107475
• ORF Size: 1410 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001107475.1, NP_001100945.1
• RefSeq Size: 2411
• RefSeq ORF: 1413
• Locus ID: 308345
• MW: 53.6 kDa
• Gene Summary: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). [UniProtKB/Swiss-Prot Function]