Nrg2 (NM_001136151) Rat Tagged ORF Clone

CAT#: RR209883

Nrg2 (Myc-DDK-tagged ORF) - Rat neuregulin 2 (Nrg2), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Nrg2
• Synonyms: Ntak; NTAK_alpha2a
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR209883 representing NM_001136151
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCGGCAGGTTTGCTGCTCAGCGCTGCCGCCGCCACTGGAGAAGGCTCGGTGCAGCAGCTACAGCTACA
  GCGACAGCAGCAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCACCAGCAGCAGAAGCAGCAGCAGAAG
  CAGCAGCAGAAGCAGCAGAGGCAGCACCACCACCACCAGCAGCAGCGAGAACAGCGGCAGCAACAGCGGC
  AGCATCTTCCGTCCCGCTGCGCCCCCAGAGCCGCGGCCGCAGCCACAGCCGCAGCCCCGCAGCCCCGCAG
  CCCGGAGAGCCGCCGCCCGCTCGCGAGCCGCAGCCGCCGGCGGCATGAGGCGCGACCCGGCCCCCGGCTC
  CTCGATGCTGCTCTTCGGTGTGTCACTCGCCTGCTACTCGCCCAGCCTCAAGTCCGTGCAGGACCAGGCG
  TACAAGGCACCCGTGGTGGTGGAGGGCAAGGTACAGGGACTGGCCCCGGCAGGCGGTTCCAGCTCTAACA
  GCACCCGAGAGCCTCCCGCCTCGGGTCGGGTGGCGCTGGTGAAGGTGCTGGACAAGTGGCCGCTCCGGAG
  CGGGGGGCTGCAGCGCGAGCAGGTGATCAGCGTGGGCTCCTGCGCGCCGCTCGAAAGGAACCAGCGCTAC
  ATCTTTTTCCTGGAGCCCACCGAGCAGCCCTTAGTTTTTAAGACAGCCTTTGCCCCGGTCGACCCTAACG
  GCAAAAACATCAAGAAAGAGGTGGGCAAGATCCTGTGCACTGACTGCGCAACCCGGCCCAAGCTGAAGAA
  GATGAAGAGTCAGACAGGAGAGGTGGGCGAGAAGCAGTCGCTCAAGTGTGAGGCGGCGGCGGGGAACCCC
  CAGCCCTCCTATCGATGGTTCAAGGACGGCAAGGAGCTCAACCGGAGTCGTGACATTCGCATCAAGTATG
  GCAACGGCAGAAAGAACTCACGGCTACAGTTCAACAAAGTGAAGGTGGAGGACGCTGGAGAGTACGTCTG
  TGAGGCTGAGAACATCCTTGGGAAGGACACTGTGAGGGGCCGGCTCCATGTCAACAGTGTGAGCACCACT
  CTGTCGTCCTGGTCGGGGCACGCCCGGAAGTGCAATGAGACAGCCAAGTCCTACTGTGTGAATGGAGGCG
  TGTGCTACTACATCGAAGGCATCAACCAACTCTCCTGCAAATGTCCAAACGGATTCTTCGGACAGAGATG
  TTTGGAGAAACTGCCTTTGCGATTGTACATGCCAGATCCTAAGCAAAAGGCTGAGGAGCTGTACCAGAAG
  AGAGTCCTGACAATTACCGGCATCTGTGTGGCTCTGCTGGTCGTGGGCATCGTCTGTGTGGTCGCCTACT
  GCAAGACTAAAAAACAGAGGAGGCAAATGCATCACCATCTCCGGCAGAACATGTGTCCGGCCCACCAGAA
  CCGAAGCCTGGCCAATGGGCCCAGCCACCCTCGGCTGGACCCTGAGGAGATCCAGATGGCAGATTACATT
  TCCAAAAATGTGCCAGCTACAGACCATGTGATCCGGAGGGAAGCTGAGACCACATTTTCTGGGAGCCACT
  CCTGTTCACCCTCTCACCACTGTTCCACAGCCACACCCACCTCCAGCCACAGACATGAGAGCCACACGTG
  GAGCTTGGAACGTTCGGAGAGCCTGACCTCGGATTCCCAGTCAGGCATCATGCTATCATCAGTGGGCACC
  AGCAAGTGCAACAGCCCAGCATGTGTGGAGGCACGGGCACGGAGGGCAGCAGCCTACAGCCAGGAGGAGC
  GACGCAGGGCTGCCATGCCACCCTACCACGACTCCATAGACTCGCTGCGTGACTCCCCACACAGTGAGAG
  GTACGTGTCAGCCCTGACCACGCCCGCGCGCCTTTCGCCCGTGGACTTCCACTACTCGCTGGCCACCCAG
  GTGCCGACTTTCGAGATCACGTCGCCCAACTCTGCCCACGCCGTGTCGCTGCCACCCGCAGCGCCCATCA
  GCTACCGCCTAGCGGAGCAGCAGCCGCTCCTGCGGCACCCAGCGCCGCCCGGCCCGGGGCCAGGGCCCGG
  AGCGGACATGCAGCGCAGCTACGACAGCTACTACTACCCGGCGGCGGGGCCCGGGCCGCGGCGCGGCGCC
  TGCGCGCTGGGAGGCAGTTTGGGCAGCCTGCCCGCCAGCCCCTTCCGCATCCCGGAGGACGACGAGTACG
  AGACCACGCAGGAGTGCGCGCCCCCGCCACCGCCGCGGCCGCGCACGCGCGGCGCGTCCCGCAGGACGTC
  GGCGGGGCCGCGGCGCTGGCGGCGCTCCCGCCTCAACGGGTTGGCTGCGCAGCGCGCACGCGCAGCGCGG
  GACTCGCTGTCGTTGAGCAGCGGTTCGGGCTGCGGCTCGGCGTCGGCCTCGGACGACGATGCGGACGACG
  CGGACGGGGCGCTGGCGGCCGAGAGCACGCCTTTCCTCGGCCTGCGAGCGGCGCACGACGCGCTGCGCTC
  GGACTCGCCGCCGCTCTGCCCGGCGGCGGACAGCAGGACTTACTACTCCCTGGACAGCCACAGCACGCGC
  GCCAGCAGCAGACACAGCCGGGGGCCGCCCACGAGGGCAAAGCAGGACTCCGGGCCCCTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR209883 representing NM_001136151
  Red=Cloning site Green=Tags(s)
  
  MRQVCCSALPPPLEKARCSSYSYSDSSSSSSSNNSSSSTSSRSSSRSSSRSSRGSTTTTSSSENSGSNSG
  SIFRPAAPPEPRPQPQPQPRSPAARRAAARSRAAAAGGMRRDPAPGSSMLLFGVSLACYSPSLKSVQDQA
  YKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCAPLERNQRY
  IFFLEPTEQPLVFKTAFAPVDPNGKNIKKEVGKILCTDCATRPKLKKMKSQTGEVGEKQSLKCEAAAGNP
  QPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLHVNSVSTT
  LSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQK
  RVLTITGICVALLVVGIVCVVAYCKTKKQRRQMHHHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYI
  SKNVPATDHVIRREAETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGT
  SKCNSPACVEARARRAAAYSQEERRRAAMPPYHDSIDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQ
  VPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPGADMQRSYDSYYYPAAGPGPRRGA
  CALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRTRGASRRTSAGPRRWRRSRLNGLAAQRARAAR
  DSLSLSSGSGCGSASASDDDADDADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTR
  ASSRHSRGPPTRAKQDSGPL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001136151
• ORF Size: 2580 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001136151.1, NP_001129623.1
• RefSeq Size: 3077
• RefSeq ORF: 2583
• Locus ID: 432361
• MW: 92.8 kDa
• Gene Summary: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor. [UniProtKB/Swiss-Prot Function]