Serpina1 (NM_022519) Rat Tagged ORF Clone

CAT#: RR210158

Serpina1 (Myc-DDK-tagged ORF) - Rat serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Serpina1
• Synonyms: AAT; Pi; Spi1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR210158 representing NM_022519
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCACCCTCCATCTCACGGGGGCTCCTGCTTCTGGCAGGCCTGTGTTGCCTGGCCCCCAGCTTCCTGG
  CTGAGGATGCCCAGGAAACCGATACCTCCCAGCAGGACCAGAGTCCAACCTACCGTAAGATTTCTTCAAA
  CCTGGCAGACTTTGCCTTCAGCCTATACCGGGAGCTGGTCCATCAATCCAATACATCCAACATCTTCTTC
  TCCCCTATGAGCATCACCACAGCCTTCGCCATGCTCTCCCTGGGGAGCAAGGGTGACACTCGCAAACAGA
  TTCTAGAGGGCCTGGAGTTCAACCTCACACAGATACCTGAGGCTGACATCCACAAGGCCTTCCATCACCT
  CCTCCAAACTCTCAACAGGCCAGACAGTGAGCTGCAGCTGAACACAGGCAATGGCCTCTTTGTCAACAAG
  AATCTGAAGCTGGTGGAGAAGTTTCTGGAAGAGGTCAAGAACAATTACCACTCAGAAGCCTTCTCTGTCA
  ACTTTGCCGACTCAGAAGAGGCTAAGAAAGTAATTAATGATTATGTAGAGAAGGGAACCCAAGGAAAGAT
  AGTTGATTTGATGAAACAGCTGGACGAAGACACGGTTTTTGCCCTGGTGAATTACATTTTCTTTAAAGGC
  AAGTGGAAGAGGCCATTCAATCCTGAGCACACTAGGGATGCTGACTTCCACGTAGACAAGTCCACCACGG
  TGAAGGTGCCCATGATGAACCGCCTGGGCATGTTTGACATGCACTATTGCAGCACACTGTCCAGCTGGGT
  GCTGATGATGGATTACCTGGGCAACGCCACTGCCATCTTCCTCCTGCCCGATGATGGCAAGATGCAGCAT
  CTGGAGCAAACTCTCACCAAGGATCTCATTTCCCGGTTCCTGCTAAACAGGCAAACAAGGTCAGCCATTC
  TCTACTTCCCCAAACTGTCCATCTCTGGAACCTATAACTTGAAGACACTCCTGAGCTCACTGGGCATCAC
  CCGGGTCTTCAACAATGATGCTGATCTCTCTGGAATCACAGAGGATGCCCCCCTGAAGCTTAGCCAGGCT
  GTGCATAAGGCTGTGCTGACCTTAGATGAGAGGGGAACAGAGGCTGCAGGAGCCACTGTGGTGGAGGCCG
  TCCCCATGTCTCTGCCCCCTCAAGTGAAGTTCGACCACCCTTTCATTTTCATGATAGTTGAATCAGAAAC
  TCAGAGCCCCCTCTTTGTGGGAAAAGTGATAGATCCCACACGT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR210158 representing NM_022519
  Red=Cloning site Green=Tags(s)
  
  MAPSISRGLLLLAGLCCLAPSFLAEDAQETDTSQQDQSPTYRKISSNLADFAFSLYRELVHQSNTSNIFF
  SPMSITTAFAMLSLGSKGDTRKQILEGLEFNLTQIPEADIHKAFHHLLQTLNRPDSELQLNTGNGLFVNK
  NLKLVEKFLEEVKNNYHSEAFSVNFADSEEAKKVINDYVEKGTQGKIVDLMKQLDEDTVFALVNYIFFKG
  KWKRPFNPEHTRDADFHVDKSTTVKVPMMNRLGMFDMHYCSTLSSWVLMMDYLGNATAIFLLPDDGKMQH
  LEQTLTKDLISRFLLNRQTRSAILYFPKLSISGTYNLKTLLSSLGITRVFNNDADLSGITEDAPLKLSQA
  VHKAVLTLDERGTEAAGATVVEAVPMSLPPQVKFDHPFIFMIVESETQSPLFVGKVIDPTR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_022519
• ORF Size: 1233 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022519.1, NM_022519.2, NP_071964.2
• RefSeq Size: 1603
• RefSeq ORF: 1236
• Locus ID: 24648
• MW: 46.1 kDa
• Gene Summary: Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin. [UniProtKB/Swiss-Prot Function]