Grk2 (NM_012776) Rat Tagged ORF Clone

CAT#: RR210490

Adrbk1 (Myc-DDK-tagged ORF) - Rat adrenergic, beta, receptor kinase 1 (Adrbk1), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Grk2
• Synonyms: Adrbk1; BARK1; GRK-2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR210490 representing NM_012776
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCGACCTGGAGGCGGTACTGGCCGATGTGAGCTACCTGATGGCCATGGAGAAGAGCAAGGCCACGC
  CGGCCGCGCGCGCCAGCAAGAAGATCCTGCTGCCAGAGCCCAGCATCCGCAGCGTCATGCAGAAGTATCT
  AGAGGATCGAGGAGAAGTGACCTTTGAAAAGATCTTCTCACAGAAGTTAGGATACCTGCTTTTCCGGGAC
  TTCTACCTGAACCATCTGGAAGAGGCCAAGCCCTTGGTGGAGTTCTATGAAGAGATCGAGAAATATGAGA
  AGCTGGAGACGGAGGAGGAACGTGTGGTCCGCAGCCGGGAGATCTTTGACTCCTACATCATGAAAGAACT
  GCTGGCCTGCTCACATCCCTTTTCAAAGAATGCCACGGAGCATGTCCAGGGCCACCTGGTGAAGAAGCAG
  GTACCTCCAGATCTCTTCCAGCCATACATTGAGGAGATTTGTCAGAACCTCCGAGGGGATGTGTTCCACA
  AATTCATTGAGAGTGACAAGTTCACACGGTTCTGCCAGTGGAAGAATGTAGAGCTCAACATCCACCTGAC
  CATGAATGACTTCAGTGTGCATCGAATCATCGGGCGTGGGGGCTTCGGTGAGGTCTATGGGTGCCGGAAA
  GCAGACACAGGCAAGATGTACGCCATGAAGTGTCTGGACAAGAAACGCATCAAGATGAAGCAGGGAGAGA
  CCCTGGCTCTGAACGAGCGGATCATGCTTTCCCTCGTCAGCACTGGGGACTGCCCCTTCATCGTGTGCAT
  GTCATATGCATTCCACACACCAGACAAGCTCAGTTTCATCCTGGATCTCATGAACGGTGGGGACCTGCAC
  TACCACTTGTCTCAGCATGGAGTCTTCTCTGAAGCCGACATGCGCTTCTACGCAGCTGAGATCATCCTGG
  GCCTTGAACACATGCACAATCGCTTTGTAGTCTACAGGGACCTAAAGCCAGCCAACATTCTCCTGGATGA
  GCATGGCCATGTGAGAATCTCAGACCTGGGCCTAGCCTGTGACTTCTCCAAGAAGAAGCCTCATGCCAGT
  GTGGGCACACACGGGTACATGGCCCCGGAAGTCCTACAGAAGGGCGTGGCCTATGACAGCAGTGCCGACT
  GGTTCTCCCTGGGCTGCATGCTCTTCAAGTTGTTGCGGGGACACAGCCCCTTCCGGCAGCACAAGACCAA
  AGACAAGCATGAGATTGACCGCATGACATTGACAATGGCTGTTGAGCTGCCTGACTCCTTCTCCCCTGAA
  CTCCGATCCCTGCTGGAAGGTTTGCTGCAGAGGGATGTCAATCGGAGACTAGGCTGTCTGGGCCGTGGGG
  CTCAAGAGATAAAAGAAAGCCCCTTCTTCCGTTCCCTGGACTGGCAGATGGTCTTCTTACAGAAGTACCC
  TCCTCCACTGATCCCCCCACGCGGGGAGGTGAATGCAGCGGACGCCTTTGACATTGGCTCCTTTGATGAG
  GAGGACACAAAAGGAATCAAGTTACTGGACAGTGACCAGGAACTGTACCGCAACTTCCCTCTCACCATCT
  CTGAGCGGTGGCAACAGGAGGTGGCAGAGACTGTCTTTGATACCATCAATGCTGAGACAGACCGGCTGGA
  GGCACGGAAGAAAGCCAAAAACAAACAGCTGGGCCACGAGGAGGACTACGCCCTGGGTAAGGACTGCATC
  ATGCATGGCTACATGTCCAAGATGGGCAACCCCTTCCTGACCCAGTGGCAGCGGCGATACTTCTACCTGT
  TCCCCAACCGGCTTGAGTGGAGGGGTGAAGACGAGGCTCCGCAGAGCCTCCTGACCATGGAAGAGATCCA
  GTCGGTGGAAGAGACACAGATCAAGGAACGCAAGTGTCTCCTGCTTAAGATCCGAGGTGGCAAGCAGTTT
  GTCCTGCAGTGTGATAGTGACCCTGAGCTGGTGCAATGGAAAAAAGAGCTGCGCGATGCTTACCGTGAGG
  CCCAGCAGCTGGTGCAGCGAGTGCCCAAGATGAAGAACAAGCCACGCTCACCTGTGGTGGAGCTGAGCAA
  GGTGCCACTGATTCAGCGTGGCAGTGCCAACGGCCTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR210490 representing NM_012776
  Red=Cloning site Green=Tags(s)
  
  MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRD
  FYLNHLEEAKPLVEFYEEIEKYEKLETEEERVVRSREIFDSYIMKELLACSHPFSKNATEHVQGHLVKKQ
  VPPDLFQPYIEEICQNLRGDVFHKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK
  ADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH
  YHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHAS
  VGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
  LRSLLEGLLQRDVNRRLGCLGRGAQEIKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDE
  EDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCI
  MHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEDEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQF
  VLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLIQRGSANGL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_012776
• ORF Size: 2067 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_012776.1, NP_036908.1
• RefSeq Size: 2683
• RefSeq ORF: 2070
• Locus ID: 25238
• MW: 79.8 kDa
• Gene Summary: catalzyes phosphorylation of the beta-adrenergic receptor; may mediate desensitizaton of synaptic receptors; may regulate bone formation [RGD, Feb 2006]