Gpx6 (NM_147165) Rat Tagged ORF Clone

CAT#: RR210731

Gpx6 (Myc-DDK-tagged ORF) - Rat glutathione peroxidase 6 (Gpx6), (10 ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Symbol: Gpx6
• Synonyms: OBPII; Ry2d1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR210731 representing NM_147165
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCCAGCAGTTCTGGGGTCCCTGTCTTTTCTCATTGTTTATGGCTGTATTGGCTCAGGAGACACTGG
  ATCCTCAAAAATCAAAGGTGGATTGCAACAAAGGGGTGGCTGGCACCGTCTATGAGTACGGAGCCAACAC
  CTTAGATGGTGGGGAGTATGTCCAGTTCCAGCAGTATGCAGGAAAGCACATTCTCTTTGTCAACGTGGCG
  TCCTTCTGTGGCCTGACAGCTACGTACCCTGAACTGAACACATTGCAGGAGGAGCTGAGACCATTCAATG
  TCAGTGTTTTGGGCTTTCCATGCAACCAGTTTGGAAAACAAGAACCTGGAAAGAACTCAGAGATCCTCCT
  TGGACTCAAATATGTTCGCCCAGGCGGTGGCTTTGTTCCCAATTTCCAGCTCTTTGAGAAGGGGGATGTG
  AACGGAGACAATGAACAAAAGGTTTTTTCTTTCCTAAAGAGCTCCTGCCCTCCCACCTCTGAACTTCTTG
  GCTCTCCAGAACATCTCTTCTGGGATCCCATGAAGGTCCATGACATTCGCTGGAACTTTGAGAAGTTCCT
  GGTGGGACCGGATGGAGCCCCTGTCATGCGCTGGTTCCACCAGACTCCTGTCAGAGTTGTCCAGTCAGAC
  ATCATGGAGTACCTAAACCAAACCCGTACCCAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR210731 representing NM_147165
  Red=Cloning site Green=Tags(s)
  
  MTQQFWGPCLFSLFMAVLAQETLDPQKSKVDCNKGVAGTVYEYGANTLDGGEYVQFQQYAGKHILFVNVA
  SFCGLTATYPELNTLQEELRPFNVSVLGFPCNQFGKQEPGKNSEILLGLKYVRPGGGFVPNFQLFEKGDV
  NGDNEQKVFSFLKSSCPPTSELLGSPEHLFWDPMKVHDIRWNFEKFLVGPDGAPVMRWFHQTPVRVVQSD
  IMEYLNQTRTQ
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_147165
• ORF Size: 663 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info The expression of this clone is not guaranteed due to the nature of selenoproteins.
• OTI Annotation: This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins.

Reference Data

• RefSeq: NM_147165.1, NP_671694.1
• RefSeq Size: 1151
• RefSeq ORF: 666
• Locus ID: 259233
• MW: 25 kDa
• Gene Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidases catalyze the reduction of a variety of hydroperoxides using glutathione as a specific electron donor substrate, and thereby protect cells against oxidative damage. Expression of this gene is restricted to embryos and adult olfactory epithelium. The mouse and rat orthologs contain a cysteine (Cys) residue at the active site, unlike the human counterpart, which is a selenoprotein, containing selenocysteine (Sec) instead. [provided by RefSeq, Jul 2017]