Axin2 (NM_024355) Rat Tagged ORF Clone

CAT#: RR212405

Axin2 (Myc-DDK-tagged ORF) - Rat axin2 (Axin2), (10 ug)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Axin2
• Synonyms: axil; axin-2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR212405 representing NM_024355
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTAGCGCTGTGTTAGTGACTCTCCTTCCAGATCCAAGCAGCAGCTTCCGCGAGGATGCTCCGCGGC
  CCCCGGTTCCCGGAGAAGAAGGGGAGACCCCACCGTGTCAGCCTAGCGTGGGCAAGGTCCAGTCCACCAA
  ACCTATGCCTGTCTCCTCTAACGCTAGGCGGAATGAAGATGGGCTGGGGGAGCCCGAGGGGCGGGCCTCC
  CCAGATTCCCCTCTGACCAGGTGGACCAAGTCTTTGCACTCCTTGTTGGGGGACCAAGATGGTGCATACC
  TCTTCCGGACTTTCCTGGAGAGGGAGAAATGTGTGGATACCCTGGACTTCTGGTTTGCCTGCAATGGGTT
  CAGGCAGATGAACTTGAAGGATACCAAAACTTTGCGAGTGGCCAAAGCAATCTACAAGAGGTACATTGAG
  AACAACAGTGTTGTCTCCAAACAGCTGAAACCCGCCACCAAGACCTACATAAGAGATGGCATCAAGAAGC
  AGCAGATCGGCTCGGTCATGTTTGACCAGGCGCAGACGGAGATTCAGGCGGTGATGGAGGAAAATGCCTA
  TCAGGTGTTCTTGACTTCTGACATATACCTCGAATATGTGAGGAGTGGGGGAGAAAACACAGCTTACATG
  AGCAATGGGGGACTGGGGAGCCTAAAGGTCTTATGTGGCTACCTCCCCACCCTGAATGAGGAAGAGGAGT
  GGACATGTGCCGACCTGAAGTGCAAACTTTCACCCACCGTGGTTGGCCTATCCAGCAAAACTCTCCGGGC
  CACAGCGAGCGTGAGATCCACAGAAACGGCTGAAAACGGATTCAGATCCTTCAAGAGAAGCGAACCGGTT
  AATCCTTATCACGTAGGTTCTGGCTATGTCTTTGCACCAGCCACCAGCGCCAACGACAGCGAGTTATCCA
  GCGACGCGCTGACCGACGATTCCATGTCCATGACAGACAGTAGCGTAGATGGAATCCCTCCTTACCGCAT
  GGGGAGTAAGAAACAACTCCAGAGAGAGATGCACCGCAGTGTGAAGGCCAATGGCCAAGTGTCTCTACCT
  CACTTCCCGAGAACCCACCGCCTGCCCAAGGAGATGACGCCCGTGGAACCTGCTGCCTTCGCCGCAGAGC
  TCATCTCCAGGCTGGAGAAGCTGAAACTGGAGCTGGAGAGCCGCCACAGCCTGGAGGAACGGCTGCAGCA
  GATCCGGGAGGATGAAGAAAAGGAGGGGTCTGAGCAGGCCCTGAGCTCACGGGATGGAGCACCGGTCCAA
  CACCCCCTGGCCCTCTTACCCTCTGGCAGCTATGAAGAGGACCCACAAACCATCTTGGACGACCACCTGT
  CCAGGGTCCTCAAGACCCCCGGCTGCCAGTCCCCTGGTGTGGGCCGCTACAGCCCACGCTCCCGCTCCCC
  CGACCACCACCACCACCACCATCAGCAGTGTCACGCCCTTCTTCCAACTGGGGGCAAGCTGCCCCCCGAG
  GCTGCTTGCCCGCTCCTTGGAGGCAAGAGCTTCCTGACCAAACAGACGACGAAGCACGTCCACCACCACT
  ACATCCACCACCACGCCGTCCCTAAGACCAAGGAGGAGATCGAGGCAGAAGCCACACAGAGAGTACGCTG
  CCTCTGCCCTGGAGGCACAGATTATTACTGCTACTCCAAGTGCAAGAGCCACTCGAAGCCTCCAGAGCCC
  CTCCCTGGGGAGCAGTTTTGTGGCAGCAGAGGTGGCACCTTGCCAAAACGGAATACGAAAGGCACAGAAC
  CGGGTCTGGCACTGCCGGCCAGGGAAGGAGGGATGTCCAGTGCAGCAGGGGCCCCTCAGCTTCCTGGGGA
  AGAAGGAGACCGGTCACAGGATGTCTGGCAGTGGATGTTGGAGAGTGAGCGTCAGAGCAAGTCCAAGCCC
  CATAGTACCCAAAGCATAAGAAAGAGCTACCCGTTGGAGTCTGCCCGCGCGCCCCCAGGCGAACGAGTCA
  GCCGGCACCATCTGCTGGGGGCCAGTGGACACCCCCGCTCAGCGGCCCGGGCTCACCCATTTACCCAGGA
  CCCTGCCATGCCTCCCCTAACCCCACCCAACACCTTGGCGCAGCTAGAGGAAGCCTGCCGCAGGCTGGCC
  GAGGTGTCAAAGCCCCAGAAACAGAGGTGCTGCGTGGCCAGTCAGCAGAGGGACAGGAACCACCCAGCCA
  CAGGTCAGGCAGGACCCACATCCTTCTCCAACCCGAGCCTGGCTTCAGAAGATCACAAAGAGCCAAAGAG
  ACTGGCTAGTGTCCACGCACTCCAAGCCAGCGAGCTGATTGTTACCTACTTTTTCTGTGGAGAAGAAATT
  CCATACAGGAGGATGCTGAAGGCGCAGAGCTTGACTCTGGGCCACTTCAAGGAGCAGCTCAGCAAAAAGG
  GAAATTACAGGTATTACTTCAAGAAGGCGAGTGACGAATTTGCCTGTGGAGCAGTCTTTGAGGAGATCTG
  GGATGATGAGACAGTGCTCCCCATGTACGAAGGCAGGATCCTGGGCAAAGTGGAGAGGATCGAC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR212405 representing NM_024355
  Red=Cloning site Green=Tags(s)
  
  MSSAVLVTLLPDPSSSFREDAPRPPVPGEEGETPPCQPSVGKVQSTKPMPVSSNARRNEDGLGEPEGRAS
  PDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFWFACNGFRQMNLKDTKTLRVAKAIYKRYIE
  NNSVVSKQLKPATKTYIRDGIKKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRSGGENTAYM
  SNGGLGSLKVLCGYLPTLNEEEEWTCADLKCKLSPTVVGLSSKTLRATASVRSTETAENGFRSFKRSEPV
  NPYHVGSGYVFAPATSANDSELSSDALTDDSMSMTDSSVDGIPPYRMGSKKQLQREMHRSVKANGQVSLP
  HFPRTHRLPKEMTPVEPAAFAAELISRLEKLKLELESRHSLEERLQQIREDEEKEGSEQALSSRDGAPVQ
  HPLALLPSGSYEEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHHHHQQCHALLPTGGKLPPE
  AACPLLGGKSFLTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVRCLCPGGTDYYCYSKCKSHSKPPEP
  LPGEQFCGSRGGTLPKRNTKGTEPGLALPAREGGMSSAAGAPQLPGEEGDRSQDVWQWMLESERQSKSKP
  HSTQSIRKSYPLESARAPPGERVSRHHLLGASGHPRSAARAHPFTQDPAMPPLTPPNTLAQLEEACRRLA
  EVSKPQKQRCCVASQQRDRNHPATGQAGPTSFSNPSLASEDHKEPKRLASVHALQASELIVTYFFCGEEI
  PYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWDDETVLPMYEGRILGKVERID
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_024355
• ORF Size: 2514 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024355.1, NP_077331.1
• RefSeq Size: 3216
• RefSeq ORF: 2517
• Locus ID: 29134
• MW: 92.9 kDa
• Gene Summary: inhibits axis formation; acts as a negative regulator of the Wnt signaling pathway by inducing GSK-3beta-dependent phosphorylation of beta-catenin [RGD, Feb 2006]