Arntl2 (NM_133391) Rat Tagged ORF Clone

CAT#: RR216928

Arntl2 (myc-DDK-tagged) - Rat aryl hydrocarbon receptor nuclear translocator-like 2 (Arntl2)

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Arntl2
• Synonyms: Arnt4; Bmal2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RR216928 representing NM_133391
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGTTTCCAAGGAAACGTAGAAGAAGTGATTCAGAGCTGCTCCAGTCAGAATTCAGGACAGATGCAA
  TGGTGGAAAACCTTCCCCGGAGTCCCTTTACCTCTGTTCTTTCAACAAGAACAGGAGTAGCAGTGCCCAA
  TGGCATCAGGGAAGCTCACAGCCAGACAGAAAAGCGTCGGAGAGACAAGATGAACCATCTGATTTGGAAA
  CTGTCATCTATGATCCCTCCACACATCCCCACAGCCCACAAACTGGACAAACTGAGCATCCTGAGGAGGG
  CAGTGCAGTACTTGAGGTCTCAGAGAGGCATGACAGAGTTTTATTTAGGAGAAAATGCTAAACCTTCATT
  TATTCAGGATAAGGAACTCAGCCACTTAATCCTCAAGGCAGCAGAAGGCTTCCTACTTGTGGTTGGATGT
  GAAGGAGGGAGAATTCTTTTCGTTTCTAAGTCTGTCTCCAAAACGCTGCATTATGATCAGGCTAGTTTGA
  TGGGACAGAACTTGTTTGACTTCTTACACCCAAAAGATGTCCCCAAAGTAAAGGAACAACTTTCTTGTGA
  TGGTTTACTAAGAGTGAAAGTTCACAGTCACTCCCATATTGGGCGATCACGCGTGCATTCTGGCTCCAGA
  CGATCTTTCTTCTTTAGAATGAAGAGCAGCTGTACAGTCCCCGTCAAAGAAGAGCAACGATGCTCGTCCT
  GTTCAAAGAAGAAAGACCAGAGAAAATTCCACACCATCCATTGCACTGGATACTTGAGAAGCTGGCCACC
  GAATGTTGTGGGCACGGAGAAAGAGATGGGCAGTGGGAAAGACAGTGGTCCTCTTACCTGCCTTGTGGCT
  ATGGGACGGTTACAGCCATATACTGTCCCCCCGAAGAATGGCAAGATCAACGTGAGACCGGCTGAGTTCA
  TAACCCGATTCGCAATGAACGGGAAATTCGTCTACGTCGACCAAAGGGCAACAGCAATTTTAGGATACCT
  GCCTGATGAACTTTTGGGAACTTCGTGTTATGAATATTTTCATCAGGATGACCACAGTAATTTGAGTGAC
  AAGCACAAAGCAGTTCTGCAGAGTAAGGAGAAAATACTTACAGATTCATACAAATTCAGAGTGAAGGATG
  GCTCCTTTGTGACTCTGAAGAGCAAGTGGTTCAGCTTCACTAACCCTTGGACCAAAAAGCTGGAGTACAT
  CGTGTCTGTCAACACGCTGGTTTTGGGGCGCAGTGAGACCGCAGTATCCGTGCCTCAGTGCCGCAGCAGC
  CAGTCCTCTGAAGACTCATTTAGACAACCCTGCGTCAGTGTGCCGGGCATATCCACAGGGACCTTACTTG
  GCGCTGGGAGTATTGGAACAGATATTGCAAATGAGGTTCTGAGTTTACAGAGGTCACACTCTTCATCCCC
  AGAAGACGCAAACCCTTCAGGAGTAGTGAGAGATAAGCACAGTGTAAACTTCGGGAGCGCCCCTGTGCCC
  GTGTCCACTGGGGAGCTCTTTGCACTGAGTCCTGAAACAGAGGGCCTGGAGGCTGCCAGGCAACACCAGA
  GTGCTGAGCCCGCCCACTGTCACAAACCACTCCTCAGTGACAGTACCCAGTTGGGTTTTGATGCCCTGTG
  TGACAGCGACGACACAGCCATGGCTACATTCATGAATTACCCCGAAGCAGAGGGTGGCCTGGGTGACCCT
  GGGGACTTCAGTGACATCCAGTGGACACTC
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RR216928 representing NM_133391
  Red=Cloning site Green=Tags(s)
  
  MEFPRKRRRSDSELLQSEFRTDAMVENLPRSPFTSVLSTRTGVAVPNGIREAHSQTEKRRRDKMNHLIWK
  LSSMIPPHIPTAHKLDKLSILRRAVQYLRSQRGMTEFYLGENAKPSFIQDKELSHLILKAAEGFLLVVGC
  EGGRILFVSKSVSKTLHYDQASLMGQNLFDFLHPKDVPKVKEQLSCDGLLRVKVHSHSHIGRSRVHSGSR
  RSFFFRMKSSCTVPVKEEQRCSSCSKKKDQRKFHTIHCTGYLRSWPPNVVGTEKEMGSGKDSGPLTCLVA
  MGRLQPYTVPPKNGKINVRPAEFITRFAMNGKFVYVDQRATAILGYLPDELLGTSCYEYFHQDDHSNLSD
  KHKAVLQSKEKILTDSYKFRVKDGSFVTLKSKWFSFTNPWTKKLEYIVSVNTLVLGRSETAVSVPQCRSS
  QSSEDSFRQPCVSVPGISTGTLLGAGSIGTDIANEVLSLQRSHSSSPEDANPSGVVRDKHSVNFGSAPVP
  VSTGELFALSPETEGLEAARQHQSAEPAHCHKPLLSDSTQLGFDALCDSDDTAMATFMNYPEAEGGLGDP
  GDFSDIQWTL
  
  SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_133391
• ORF Size: 1710 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_133391.1, NP_596882.1
• RefSeq Size: 1928
• RefSeq ORF: 1647
• Locus ID: 362464
• MW: 63.5 kDa
• Gene Summary: This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (Per, Arnt, Sim) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian Clock protein, the structurally related Mop4, and hypoxia-inducible factors, such as Hif1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. [provided by RefSeq, Feb 2014]