Myotrophin (MTPN) (NM_145808) Human Untagged Clone

CAT#: SC100218

MTPN (untagged)-Human myotrophin (MTPN)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MTPN
• Synonyms: GCDP; V-1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100218 sequence for NM_145808 edited (data generated by NextGen Sequencing)
  ATGTGCGACAAGGAGTTCATGTGGGCCCTGAAAAACGGAGACTTGGATGAGGTGAAAGAC
  TATGTGGCCAAGGGAGAAGATGTCAACCGGACACTAGAAGGTGGAAGGAAACCTCTTCAT
  TATGCAGCAGATTGTGGGCAGCTTGAAATCCTGGAATTTCTGCTGCTGAAAGGAGCAGAT
  ATTAATGCTCCAGATAAACATCATATTACTCCTCTTCTGTCTGCTGTCTATGAGGGTCAT
  GTTTCCTGTGTGAAATTGCTTCTGTCAAAGGGTGCTGATAAGACTGTGAAAGGCCCAGAT
  GGACTGACCGCCTTTGAAGCCACTGACAACCAGGCAATCAAAGCTCTTCTCCAGTGA
  
  Clone variation with respect to NM_145808.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145808 unedited
  TCAAAATTTGTAATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGGCCTCGGCC
  AGGCGGAACCTCTCTGCTGGGCCCGGTGGCCGCAAAAGAACTTTCTTTCTCCCGCCCGAA
  CGGTCGCCGCGGCCAACTGCCTCGCCCGCCTGGCAGCCTAACCCTCCTTCTCTTCTTCTC
  CTCTCCGGCTTCGCGCGGCCCTGCCTCCCTCTCGCCCGGCGGCATCCGCTTGCTGCTGCC
  ACCGCCTCCTCATCTTCTGCCCGGCCAACCGGCCTGCCCCGCTGCAGTGATGTGCGACAA
  GGAGTTCATGTGGGCCCTGAAAAACGGAGACTTGGATGAGGTGAAAGACTATGTGGCCAA
  GGGAGAAGATGTCAACCGGACACTAGAAGGTGGAAGGAAACCTCTTCATTATGCAGCAGA
  TTGTGGGCAGCTTGAAATCCTGGAATTTCTGCTGCTGAAAGGAGCAGATATTAATGCTCC
  AGATAAACATCATATTACTCCTCTTCTGTCTGCTGTCTATGAGGGTCATGTTTCCTGTGT
  GAAATTGCTTCTGTCAAAGGGTGCTGATAAGACTGTGAAAGGCCCAGATGGACTGACCGC
  CTTTGAAGCCACTGACAACCAGGCAATCAAAGCTCTTCTCCAGTGATGGATGGATGGACT
  GATAACTCCGGAAGAATGACTCTNCTGTGGCCTCACACTGCTGCCTGTCTGTCTGTCACT
  CTCTATCTGCCAGCTTCTTCAGCTAAATACTTTAAGAGGGGTGANNGGGGAGAGAGAAAT
  TCATAACAAATCCGACTACCAGAAAAAAAAATTGTTTTTGGAGGAGGGCANAAGAACCAT
  GATCAGGGCTTTACTGGGATTCCTGATCAGTAAGCCTCTCCCTTTCTAATNAATATACAC
  TTATACCCAGGGAGAGCAAGACAAATACACAGTACATTGACCCTTTCACTCCTACTAATT
  ATAAATGGGGTGGAAGCCTGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_145808 unedited
  NNGGGTATAGCTATGNACGCGGCCGCATTCTNANATCGAGTTTTTTTTTTTTTTTTTTGT
  AGCACAATTCAAGTTTATTCCATTTGTTCTTGCAACACAAAACTTAAAACACAGTATTAT
  TTAGCATTCGGATGTACATGAACTAGGATACTTATGAGAAACCCAACTGCGTCAAAAGTA
  TGACATTGTGGAAAAAATGAACTCAAATATATCAAAATGCACAAAGCACTAGTCTTCCTC
  CATTACCGCTTAGAAAGATATGATTGTTTCTCCATTTACAAAATAGAATCAGGACAATTT
  AAATTTTTTATATTTTGCATGCAAAACACTGCAATTGCTTATTTATGTAGGAGGGCACTC
  TCACCAGCTTCTTCTATACACAATTGAGTATACAATATTGCATGGAAGAAAACAGCAGCT
  CAACTGAAATATTAGAAAAAAAAATCAAACAGATACATACAGATTTAAAATCCAGTACTT
  GGGAAAAGATATCAATGAATAAAAGGCCTACTTGTTTGCAGCTTCCACACACTGCACCTA
  CCTACTACCTCTCTTCCATGCTTAACTGGGTTTAGAAAGGTGAGCTATGCGTAGAAGAAC
  TACTTGGGATATTCAAGTGCTGTATTTGAACGATAAGCCTATAGATAACAGTCTGAAGCT
  GCCAGGGAGACTTTGTTAGTACACTACTATAAACAGGTAAACTACCCTGTTTGGACTTGA
  AATAGTGCATATGGAATGACTGATTTAATACAAAACTTCCGAACATGCCAAATTTTTTCT
  GAGATGGTAAGTATTAACTTCCGTGGGAGACAAAAACTTACTCAAACCTTCGGCTAATGC
  CTGTGGTACCCCAAAGCCAACAGGTTTTAAGCCTCCCTTACTCAAAAATGAACTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_145808
• ORF Size: 357 bp
• Insert Size: 3800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_145808.1, NP_665807.1
• RefSeq Size: 3770
• RefSeq ORF: 357
• Locus ID: 136319
• Domains: ANK
• Gene Summary: The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]