CNTF Receptor alpha (CNTFR) (NM_147164) Human Untagged Clone

CAT#: SC100275

CNTFR (untagged)-Human ciliary neurotrophic factor receptor (CNTFR), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CNTFR
• Synonyms: MGC1774
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_147164 edited
  GAATTCGGCACGAGGGGCGGCGGCAGCGGAGGCGGCGGCTCCAGCCGGCGCGGCGCGAGG
  CTCGGCGGTGGGATCCGGCGGGCGGTGCTAGCTCCGCGCTCCCTGCCTCGCTCGCTGCCG
  GGGGCGGTCGGAAGGCGCGGCGCGAAGCCCGGGTGGCCCGAGGGCGCGACTCTAGCCTTG
  TCACCTCATCTTGCCCCCTTGGTTTTGGAAGTCCTGAAGAGTTGGTCTGGAGGAGGAGGA
  GGACATTGATGTGCTTGGTGTGTGGCCAGTGGTGAAGAGATGGCTGCTCCTGTCCCGTGG
  GCCTGCTGTGCTGTGCTTGCCGCCGCCGCCGCAGTTGTCTACGCCCAGAGACACAGTCCA
  CAGGAGGCACCCCATGTGCAGTACGAGCGCCTGGGCTCTGACGTGACACTGCCATGTGGG
  ACAGCAAACTGGGATGCTGCGGTGACGTGGCGGGTAAATGGGACAGACCTGGCCCCTGAC
  CTGCTCAACGGCTCTCAGCTGGTGCTCCATGGCCTGGAACTGGGCCACAGTGGCCTCTAC
  GCCTGCTTCCACCGTGACTCCTGGCACCTGCGCCACCAAGTCCTGCTGCATGTGGGCTTG
  CCGCCGCGGGAGCCTGTGCTCAGCTGCCGCTCCAACACTTACCCCAAGGGCTTCTACTGC
  AGCTGGCATCTGCCCACCCCCACCTACATTCCCAACACCTTCAATGTGACTGTGCTGCAT
  GGCTCCAAAATTATGGTCTGTGAGAAGGACCCAGCCCTCAAGAACCGCTGCCACATTCGC
  TACATGCACCTGTTCTCCACCATCAAGTACAAGGTCTCCATAAGTGTCAGCAATGCCCTG
  GGCCACAATGCCACAGCTATCACCTTTGACGAGTTCACCATTGTGAAGCCTGATCCTCCA
  GAAAATGTGGTAGCCCGGCCAGTGCCCAGCAACCCTCGCCGGCTGGAGGTGACGTGGCAG
  ACCCCCTCGACCTGGCCTGACCCTGAGTCTTTTCCTCTCAAGTTCTTTCTGCGCTACCGA
  CCCCTCATCCTGGACCAGTGGCAGCATGTGGAGCTGTCCGACGGCACAGCACACACCATC
  ACAGATGCCTACGCCGGGAAGGAGTACATTATCCAGGTGGCAGCCAAGGACAATGAGATT
  GGGACATGGAGTGACTGGAGCGTAGCCGCCCACGCTACGCCCTGGACTGAGGAACCGCGA
  CACCTCACCACGGAGGCCCAGGCTGCGGAGACCACGACCAGCACCACCAGCTCCCTGGCA
  CCCCCACCTACCACGAAGATCTGTGACCCTGGGGAGCTGGGCAGCGGCGGGGGACCCTCG
  GCACCCTTCTTGGTCAGCGTCCCCATCACTCTGGCCCTGGCTGCCGCTGCCGCCACTGCC
  AGCAGTCTCTTGATCTGAGCCCGGCACCCCATGAGGACATGCAGAGCACCTGCAGAGGAG
  CAGGAGGCCGGAGCTGAGCCTGCAGACCCCGGTTTCTATTTTGCACACGGGCAGGAGGAC
  CTTTTGCATTCTCTTCAGACACAATTTGTGGAGACCCCGGCGGGCCCGGGCCTGCCGCCC
  CCCAGCCCTGTCGCACCAAGCTGGCCCTCCTTCCTCCCTCAGGGGAGGTGGGCCATGCAG
  CTAACCCACCCACCAAAGACCCCCTCACCCTGGCCCCTTGGGCTGGACCCTCCAATGCCA
  GCGACTCCCAGGAGCCCTTGGGGGACGTGAGGGGAGCCTCTCACATCCGATTTCTCCTCC
  TGCCCCAGCCTCCTGTCTATCCCAGGGTCTCTGTTGCCACCATCAGATTATAAGCTCCTG
  ATGCTGGGGGGGCCCAGCCATCCCCCTCCCCCCAGCACCCACAATTTTCAGTCCCCTCCC
  CTCTGCCCTGTTTTGTATACCCCTCCCCTGACCCTGCTCCTATCCCACAGTATTTAATGC
  CCTGTCAGTCCCTTCTAGTCTGACTCAATGGTAACTTGCTGTATTTGAATTTTTTATAGA
  TGTATATACAGGGTGGGGGGAGTGGGCGGTTCTCATTAAACGTCACCATTTCATGAAAAA
  AAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_147164 unedited
  GTTGCACCAATAGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCGGCGGC
  AGCGGAGGCGGCGGCTCCAGCCGGCGCGGCGCGAGGCTCGGCGGTGGGATCCGGCGGGCG
  GTGCTAGCTCCGCGCTCCCTGCCTCGCTCGCTGCCGGGGGCGGTCGGAAGGCGCGGCGCG
  AAGCCCGGGTGGCCCGAGGGCGCGACTCTAGCCTTGTCACCTCATCTTGCCCCCTTGGTT
  TTGGAAGTCCTGAAGAGTTGGTCTGGAGGAGGAGGAGGACATTGATGTGCTTGGTGTGTG
  GCCAGTGGTGAAGAGATGGCTGCTCCTGTCCCGTGGGCCTGCTGTGCTGTGCTTGCCGCC
  GCCGCCGCAGTTGTCTACGCCCAGAGACACAGTCCACAGGAGGCACCCCATGTGCAGTAC
  GAGCGCCTGGGCTCTGACGTGACACTGCCATGTGGGACAGCAAACTGGGATGCTGCGGCG
  ACGTGGCGGGTAAATGGGACAGACCTGGCCCCTGACCTGCTCAACGGCTCTCAGCTGGTG
  CTCCATGGCCTGGAACTGGGCCACAGTGGCCTCTACGCCTGCTTCCACCGTGACTCCTGG
  CACCTGCGCCACCAAGTCCTGCTGCATGTGGGCTTGCCGCCGCGGGAGCCTGTGCTCAGC
  TGCCGCTCCACACTTACCCCAAGGGCTTCTACTGCAGCTGGCATCTGCCCACCCCACCTA
  CATTCCCAACACCTTCAATGTGACTGTGCTGCATGGCTCCAAAATATGGCCCGTGAGGAA
  GACCCANCCTCAATAACCGTTGCACATTCCCTACATGCACCTGTTCTCCACCATCAATTA
  CAAAGTCTCCATAAGTGTCCAGCATGCCCTGGGCCACATGCCCCAGTTTCACCTTTGACG
  AGTTCCCATTGTGAACCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_147164 unedited
  TTAGCTTGGCCGCGGCCGCATCTANAGTCGGTTTTTTTTTTTTTTTTTTCATGAAATGGT
  GACGTTTAATGAGAACCGCCCACTCCCCCCACCCTGTATATACATCTATAAAAAATTCAA
  ATACAGCAAGTTACCATTGAGTCAGACTAGAAGGGACTGACAGGGCATTAAATACTGTGG
  GATAGGAGCAGGGTCAGGGGAGGGGTATACAAAACAGGGCAGAGGGGAGGGGACTGAAAA
  TTGTGGGTGCTGGGGGGAGGGGGATGGCTGNNCCCCCCCANCNTCACGAGCTTATAATCT
  GATGGTGGCAACAGAGACCCTGGGATAGACAGGAGGCTGGGGCAGGAGGAGAAATCGGAT
  GTGAGAGGCTCCCCTCACGTCCCCCAAGGGCTCCTGGGAGTCGCTGGCATTGGAGGGTCC
  AGCCCAAGGGGCCAGGGTGAGGGGGCCTTTGGTGGGTGGGCCCCTTGCCTGGCCCACCTC
  CCCTGACGCAGGCAAGATGCCCCACCCGCCGCCATTGACCCCGCCGGCGCGCCGCACCCG
  TCCCCTCTCCTTCCTTCCCTTCCCCCCTTCCCCCTGTCTCGCGGCCCCCTCTGACCGCGC
  GTCTCCCCTCCCGTCTCCCCCCCCTCCCCGCCCCCCTCTCGCCCCTGTCTGCGTCGCCGC
  CGTTTTTCTCTACCCTCCTCTCTCTTCTTCATCAGCCCCCCCCCTCCCCGCTCCTTCCTT
  CTTCTCACTCCCCCCCCACACAAAGTACCAACGCTCCCGCGGTTTTATCATATTTTTTCC
  CATCCTCCCCCTCCCCCGCCCCCCTCCGAATCCTTGCCCCGCCCCGTCCCCCCCCCCCCC
  ACCCCTTCTCCCTTCCCCGCCTTCTCTTTTTCCTCTATCTCTGACTCTCGCCCCCCTTTC
  TGCGCTTCCCCCTTCCCCTCTCTCTCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_147164
• Insert Size: 2170 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_147164.1, NP_671693.1
• RefSeq Size: 2055 bp
• RefSeq ORF: 1119 bp
• Locus ID: 1271
• Cytogenetics: 9p13.3
• Domains: ig, IGc2, IG, FN3
• Protein Families: Druggable Genome
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: 'This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]'
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.