ABHD12 (NM_015600) Human Untagged Clone

CAT#: SC100450

ABHD12 (untagged)-Human abhydrolase domain containing 12 (ABHD12), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABHD12
• Synonyms: ABHD12A; BEM46L2; C20orf22; dJ965G21.2; hABHD12; PHARC
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015600, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGAAGCGGACCGAGCCCGTCGCCTTGGAGCATGAGCGCTGCGCCGCCGCGGGCTCGTCCTCCTCCG
  GCTCGGCCGCCGCGGCGCTGGACGCCGACTGCCGCCTGAAGCAGAACCTACGCCTGACGGGCCCGGCGGC
  GGCTGAGCCGCGCTGCGCAGCCGACGCGGGAATGAAGCGGGCGCTGGGCAGGCGAAAGGGCGTGTGGTTG
  CGCCTGAGGAAGATACTTTTCTGTGTTTTGGGGTTGTACATTGCCATTCCATTTCTCATCAAACTATGTC
  CTGGAATACAGGCCAAACTGATTTTCTTGAATTTCGTAAGAGTTCCCTATTTCATTGATTTGAAAAAACC
  ACAGGATCAAGGTTTGAATCACACGTGTAACTACTACCTGCAGCCAGAGGAAGACGTGACCATTGGAGTC
  TGGCACACCGTCCCTGCAGTCTGGTGGAAGAACGCCCAAGGCAAAGACCAGATGTGGTATGAGGATGCCT
  TGGCTTCCAGCCACCCTATCATTCTGTACCTGCATGGGAACGCAGGTACCAGAGGAGGCGACCACCGCGT
  GGAGCTTTACAAGGTGCTGAGTTCCCTTGGTTACCATGTGGTCACCTTTGACTACAGAGGTTGGGGTGAC
  TCAGTGGGAACGCCATCTGAGCGGGGCATGACCTATGACGCACTCCACGTTTTTGACTGGATCAAAGCAA
  GAAGTGGTGACAACCCCGTGTACATCTGGGGCCACTCTCTGGGCACTGGCGTGGCGACAAATCTGGTGCG
  GCGCCTCTGTGAGCGAGAGACGCCTCCAGATGCCCTTATATTGGAATCTCCATTCACTAATATCCGCGAA
  GAAGCTAAGAGCCATCCATTTTCAGTGATATATCGATACTTCCCTGGGTTTGACTGGTTCTTCCTTGATC
  CTATTACAAGTAGTGGAATTAAATTTGCAAATGATGAAAACGTGAAGCACATCTCCTGTCCCCTGCTCAT
  CCTGCACGCTGAGGACGACCCGGTGGTGCCCTTCCAGCTTGGCAGAAAGCTCTATAGCATCGCCGCACCA
  GCTCGAAGCTTCCGAGATTTCAAAGTTCAGTTTGTGCCCTTTCATTCAGACCTTGGCTACAGGCACAAAT
  ACATTTACAAGAGCCCTGAGCTGCCACGGATACTGAGACCTCAGCAGGGCCCAGGTTCCAGCCCAGATCC
  CAGCATGTGGTCAGAGCTGGTGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015600 unedited
  GGTGTTCACATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCGGGCTGTGA
  GCGGCGGCACTGCGGCGCAGGCCAGCGGGCGCCGTCGGCGGCTGGCCCTGTCGGCCGCGG
  GATGAGGAAGCGGACCGAGCCCGTCGCCTTGGAGCATGAGCGCTGCGCCGCCGCGGGCTC
  GTCCTCCTCCGGCTCGGCCGCCGCGGCGCTGGACGCCGACTGCCGCCTGAAGCAGAACCT
  ACGCCTGACGGGCCCGGCGGCGGCTGAGCCGCGCTGCGCAGCCGACGCGGGAATGAAGCG
  GGCGCTGGGCAGGCGAAAGGGCGTGTGGTTGCGCCTGAGGAAGATACTTTTCTGTGTTTT
  GGGGTTGTACATTGCCATTCCATTTCTCATCAAACTATGTCCTGGAATACAGGCCAAACT
  GATTTTCTTGAATTTCGTAAGAGTTCCCTATTTCATTGATTTGAAAAAACCACAGGATCA
  AGGTTTGAATCACACGTGTAACTACTACCTGCAGCCAGAGGAAGACGTGACCATTGGAGT
  CTGGCACACCGTCCCTGCAGTCTGGTGGAAGAACGCCCAAGGCAAAGACCAGATGTGGTA
  TGAGGATGCCTTGGCTTCCAGCCACCCTATCATTCTGTACCTGCATGGGAACGCAGGTAC
  CAGAGGAGGCGACCACCGCGTGGAGCTTTACAGGTGCTGAGTTCCCTTGGTTACCATGTG
  GTCACCTTTGACTACAGAGGTTGGGGTGACTCAGTGGGAACGCCATCTGAGCGGGGCATG
  ACCTATGACGCACTCCACGTTTTTGACTGGATCAAAGCAAGAAGTGGTGANCACCCCGTG
  TACATCTGGGGCCACTCTCTGGGCACTGGCGTGGCGACAAATCTGGTGCGGCGCCTCTGT
  GAGCGAGAGACN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015600
• ORF Size: 1215 bp
• Insert Size: 1750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015600.2, NP_056415.1
• RefSeq Size: 1751
• RefSeq ORF: 1215
• Locus ID: 26090
• Protein Families: Protease, Transmembrane
• Gene Summary: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2011]
  Transcript Variant: This variant (2) uses an alternate 3' terminal exon compared to variant 1, resulting in a longer isoform (b) with a distinct C-terminus compared to isoform a.