SELH (SELENOH) (NM_170746) Human Untagged Clone

CAT#: SC100672

C11orf31 (untagged)-Human chromosome 11 open reading frame 31 (C11orf31) (10ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)

Specifications

Product Data

• Type: Human Untagged Clone
• Symbol: SELENOH
• Synonyms: C11orf31; C17orf10; SELH
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100672 sequence for NM_170746 edited (data generated by NextGen Sequencing)
  ATGGCTCCCCGCGGGAGGAAGCGTAAGGCTGAGGCCGCGGTGGTCGCCGTAGCCGAGAAG
  CGAGAGAAGCTGGCGAACGGCGGGGAGGGAATGGAGGAGGCGACCGTTGTTATCGAGCAT
  TGCACTAGCTGACGCGTCTATGGGCGCAACGCCGCGGCCCTGAGCCAGGCGCTGCGCCTG
  GAGGCCCCAGAGCTTCCAGTAAAGGTGAACCCGACGAAGCCCCGGAGGGGCAGCTTCGAG
  GTGACGCTGCTGCGCCCGGACGGCAGCAGTGCGGAGCTCTGGACTGGGATTAAGAAGGGG
  CCCCCACGCAAACTCAAATTCCCTGAGCCTCAAGAGGTGGTGGAAGAGTTGAAGAAGTAC
  CTGTCGTAG
  
  Clone variation with respect to NM_170746.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_170746 unedited
  GCACGAGGGTTTCCGCTGTAGGAGCAGAGCTTCCGGGCTGCGCTCTTCGTTGCCCAGTTT
  CCGCTCAGTGGTCGCGTCTCCGCCCCCCACCCACCAGTCCCGCTGCATTCTCGGCCGGGC
  TCTAGGCGCCATGGCTCCCCGCGGGAGGAAGCGTAAGGCTGAGGCCGCGGTGGTCGCCGT
  AGCCGAGAAGCGAGAGAAGCTGGCGAACGGCGGGGAGGGAATGGAGGAGGCGACCGTTGT
  TATCGAGCATTGCACTAGCTGACGCGTCTATGGGCGCAACGCCGCGGCCCTGAGCCAGGC
  GCTGCGCCTGGAGGCCCCAGAGCTTCCAGTAAAGGTGAACCCGACGAAGCCCCGGAGGGG
  CAGCTTCGAGGTGACGCTGCTGCGCCCGGACGGCAGCAGTGCGGAGCTCTGGACTGGGAT
  TAAGAAGGGGCCCCCACGCAAACTCAAATTCCCTGAGCCTCAAGAGGTGGTGGAAGAGTT
  GAAGAAGTACCTGTCGTAGGGAGATTTGGGTAGAAGCCCTCATGCTGAGCTTTGTGTCCC
  TGGTGATGTTGGAACATTAATGATGGAACATGGCCAAACTTCAGTCATGATCCTGAAGCC
  ATGGTTTCTTCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_170746
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). The expression of this clone is not guaranteed due to the nature of selenoproteins.
• OTI Annotation: This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins.

Reference Data

• RefSeq: NM_170746.2, NP_734467.1
• RefSeq Size: 1294
• Locus ID: 280636
• Gene Summary: This gene encodes a nucleolar protein, which belongs to the SelWTH family. It functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2016]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.