MLC1 (NM_015166) Human Untagged Clone

CAT#: SC102570

MLC1 (untagged)-Human megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MLC1
• Synonyms: LVM; MLC; VL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC102570 sequence for NM_015166 edited (data generated by NextGen Sequencing)
  ATGACCCAGGAGCCATTCAGAGAGGAGCTGGCCTATGACCGGATGCCCACGCTGGAGCGG
  GGCCGGCAAGACCCCGCCAGCTATGCCCCAGACGCGAAGCCGAGCGACCTGCAGCTGTCG
  AAGAGACTGCCCCCCTGCTTCAGCCACAAGACGTGGGTCTTCTCTGTGCTGATGGGGAGC
  TGCCTCCTGGTGACCTCGGGGTTTTCGCTGTACCTGGGGAACGTGTTCCCGGCTGAGATG
  GATTACTTGCGCTGTGCTGCAGGCTCTTGCATCCCCTCGGCAATTGTGAGCTTCACCGTC
  TCCAGGAGGAACGCCAATGTGATTCCCAACTTTCAGATATTGTTTGTTTCCACGTTTGCT
  GTGACCACTACGTGTTTAATTTGGTTTGGATGCAAACTAGTCCTGAACCCATCAGCAATA
  AACATCAACTTCAACCTCATCCTGCTGCTCCTGCTGGAGCTGCTCATGGCGGCCACGGTG
  ATCATCGCTGCACGGTCCAGCGAGGAGGACTGCAAGAAAAAGAAGGGCTCCATGTCTGAC
  AGCGCCAACATTCTGGACGAAGTGCCATTTCCTGCTCGGGTCCTGAAATCTTACTCAGTC
  GTCGAGGTAATCGCAGGCATCTCTGCCGTCCTCGGGGGGATCATTGCCCTGAACGTGGAT
  GACTCAGTTTCAGGCCCACACCTCTCAGTGACGTTCTTTTGGATCCTAGTGGCCTGCTTT
  CCAAGTGCCATTGCCAGTCATGTGGCAGCAGAGTGTCCCAGCAAGTGTCTGGTGGAGGTC
  CTGATTGCCATAAGCAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCA
  TTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAAAACCATCC
  TACGATGTGCTGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACG
  GGCACCGCCATCCAGTGCGTGCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGG
  GACACCCAGAACGGCCCGCAGGAGCGCCTGGCTGGGGAGGTGGCCAGGAGCCCCCTGAAG
  GAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGCAAATGGCCCAGTGA
  
  Clone variation with respect to NM_015166.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015166 unedited
  ATTTTGTAATACGACTTACTATAGGGCGGCCCGCGATTCGGCACGAGGCGTTGAGTAGAG
  GCATGTTTTGCAATCTCTCGTTTAGCTACCAATTGGAGCAGTTTAACGTGCTTGAGTCCC
  CGGCGTGATGTGTTCATGGACGAAGTTGCCGATGGATGTTGTCAGGTGTTGCACCTGGAG
  GGCCCAGATGGATCAATGAGGCATTTAAAGTGTAGAATCTCACCCTGAACCCAGACTATT
  CAGGTCCGTTTTTCTAGGAAAGTTATTTCTTTTTCACTTTTAGATTCAAGTGCTCATTTT
  CTTCTTCAAATTTAGAGCACTTCAGTATGAACAATATTTCTTTTGTTAAAAAATATTTCT
  TGGAAACAACTTATTGAGGTTTCCTCAGAGTGGCCAAAGCCGATGATAATTTTATTCCAG
  ATAAAGAACTGGTGACACGTGGCTGTACATTCAGCACAGCTGTGGTGTCCCCAAGTGCCA
  TGACCCAGGAGCCATTCAGAGAGGAGCTGGCCTATGACCGGATGCCCACGCTGGAGCGGG
  GCCGGCAAGACCCCGCCAGCTATGCCCCAGACGCGAAGCCGAGCGACCTGCAGCTGTCGA
  AGAGACTGCCCCCCTGCTTCAGCCACAAGACGTGGGTCTTCTCTGTGCTGATGGGGAGCT
  GCCTCCTGGTGACCTCGGGGTTTTCGCTGTACCTGCGGAACGTGTTCCCGGCTGAGATGG
  ATTACTTGCGCTGTGCTGCAGGCTCTTGCATCCCCTTCGCCATTGTGAGCTTCACCGTCT
  CCAGNAGGAACGCCAATGTGATTCCCAACTTTCAGATATTGTTGTTTCCACGCTTGCTGT
  GACCACTACGTGTTTAATTTGGGTTTGGATGCAACTAGTTCTGAACCCATTAGCATTAAC
  CATTACTTCACCTCATCCTGCTGCTCCTGCTGGAGCTGCTCATTGGGGCCCAGTGATCAT
  TCGTGACGTTCCACGCAGAAGACTGCATA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015166 unedited
  GGGTTTAGCTATGNANCGCGGCCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTGC
  AGTCAGCGTTTATGCTCAGCGTTTAAACAAAAAGTAGACTGAAAGAGAAGTTCTTTTAAA
  CCCCATTTTTCACGATTTTTTAAGCGCTCTAAAATAAGAAAATAAGAAAGTGCAAGCCAG
  CAAAAACGCTCCAAGTGCCTAATTCTGACTCTGAAACTTGAGCTCTCTGGTCTGCCCCCA
  AGAAGACATCAGCCCGCCCCGGGTCGTCCCTGTGGCTCCCACCCCATTCCCAGGAGCAGA
  CCCCGCCAGCCTCAAAGCTGCAGGGAGGTGGGGGTGGCCTGCAGACAGGGTGGGGTCTGC
  ATCCGGTACCAGTGACAGCAGCCTCTCCTCTCCCACGGTGGCGCTTGTTTGGGGCTGTGG
  CCAAAGTGTTTGCCCGGCCCCTGACTGTGTCCTTCCGGAGCTGCCGAGGACTGAAGAGAG
  GGCCTGGCTTGTCCCCTCTAGGAGCAGCTGGGAAGGTGTCTTGCCTGCATCCCCCTTCAA
  TGGTTGAAAATAATGATTCCACTTGTCATGAACACCATGAAGGTATCTTGGCAGCCAGAG
  TCACTCCTGTTCCGCAGTGGGAAACCTGGGAGGGTCCTCAAACCCCCTGGCAGGGTCTGC
  AGGCCCGCCCCATTCAGCTGCATCTCCCAAGCCTCCTGGTTCTTTTGATCTTGATGGCCC
  CAAGCCACAGATGCATCTTCGGGCCTTTCCAGCAGCCCATGGGGGACCAGCCAATACACC
  CCCACGGGGGTGGAAGAGAAAACGTTAATGTCTTTCTCAGATCAGAAGGAAAGAACCAAA
  CCCTTGCTGAAGAAAACACTGCTGGAAGTAATTATAAAGTAACAGCATTCCAGTTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015166
• ORF Size: 1134 bp
• Insert Size: 4230
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015166.2, NP_055981.1
• RefSeq Size: 3516
• RefSeq ORF: 1134
• Locus ID: 23209
• Protein Families: Ion Channels: Other, Transmembrane
• Gene Summary: The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.