ROC2 (RNF7) (AF312226) Human Untagged Clone

CAT#: SC106228

(untagged)-Human SAG splice variant mRNA, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF7
• Synonyms: CKBBP1|ROC2|SAG
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for AF312226 edited
  ATGGCCGACGTGGAAGACGGAGAGGAAACCTGCGCCCTGGCCTCTCACTCCGGGAGCTCA
  GGCTCCAAGTCGGGAGGCGACAAGATGTTCTCCCTCAAGAAGTGGAACGCGGTGGCCATG
  TGGAGCTGGGACGTGGAGTGCGATACGTGCGCCATCTGCAGGGTCCAGGTGATGGATGCC
  TGTCTTAGATGTCAAGCTGAAAACAAACAAGAGGACTGTGTTGTGGTCTGGGGAGAATGT
  AATCATTCCTTCCACAACTGCTGCATGTCCCTGTGGGTGAAACAGAACAATCGCTGCCCT
  CTCTGCCAGCAGGACTGGGTGGTCCAAAGAATCGGCAAATGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AF312226 unedited
  CAACATTTTGGTAATACGACTCACTATAGGGCGGCCGCGAATTCGCACCAGGCGGCCTGC
  GGGCGGCGCTGTGGCCCGTCGGGCGGCTCCACAGAGCCGCCCTAGCCTTCCGCCTTCCCC
  AAGCCAACGTCTCCGCCGTCGGCTCCGCGGCGCCGCCATGGCCGACGTGGAAGACGGAGA
  GGAAACCTGCGCCCTGGCCTCTCACTCCGGGAGCTCAGGCTCCAAGTCGGGAGGCGACAA
  GATGTTCTCCCTCAAGAAGTGGAACGCGGTGGCCATGTGGAGCTGGGACGTGGAGTGCGA
  TACGTGCGCCATCTGCAGGGTCCAGGTGATGGATGCCTGTCTTAGATGTCAAGCTGAAAA
  CAAACAAGAGGACTGTGTTGTGGTCTGGGGAGAATGTAATCATTCCTTCCACAACTGCTG
  CATGTCCCTGTGGGTGAAACAGAACAATCGCTGCCCTCTCTGCCAGCAGGACTGGGTGGT
  CCAAAGAATCGGCAAATGAGAGTGGTTAGAAGGCTTCTTAGCGCAGTTGTTCAGAGCCCT
  GGTGGATCTTGTAATCCAGTGCCCTACAAAGGCTAGAACACTACAGGGGATGAATTCTTC
  AAATAGGAGCCGATGGATCTGTGGTCCTTTGGGACTCATCAAAGCCTTGGTTTAGCATTT
  TGTCAGTTTTATCTTCAGAAATTCTCTGCGATTAAGAAGATAATTTATTAAAGGTGGTCC
  TTCCTACCTCTGTGGTGTGTGTCGCGCACACAGCTTAGAAGTGCTATAAAAAAGGAAAGA
  GCTCCAAATTGAATCACCTTNTATATTTACCCATTTCTATANCACAGGCAGTGGAAGCAG
  TTTCAGAGAACTTTTTGCATGCTTATGGGTGATCAGTTAANAAAAGATGGTACANNGTAC
  AATAAAGTGCAGTTTAAACCCCACTCCTACTCTTAAATTTGTCCTATACGTATTTTTGGC
  AGGGAGAGGGAACGTCCATGNAATCTTTTGTGAAAT
  
• Restriction Sites: NotI-NotI
• ACCN: AF312226
• ORF Size: 327 bp
• Insert Size: 2850
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: AF312226.1, AAK37450.1
• RefSeq Size: 674
• RefSeq ORF: 327
• Locus ID: 9616
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]