Nesprin 2 (SYNE2) (NM_182913) Human Untagged Clone

CAT#: SC107647

SYNE2 (untagged)-Human spectrin repeat containing, nuclear envelope 2 (SYNE2), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SYNE2
• Synonyms: EDMD5; KASH2; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; TROPH
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107647 sequence for NM_182913 edited (data generated by NextGen Sequencing)
  ATGGAAGACCCCAGAGAAATCCAGACTGATTCTTGGCGTAAACGGGGAGAGAGCGAGGAA
  CCGTCATCTCCTCAGTCCCTGTGTCATCTAGTGGCCCCAGGGCACGAGCGGTCTGGCTGC
  GAGACCCCTGTCAGCGTGGACTCCATCCCCCTGGAGTGGGACCACACAGGCGACGTGGGG
  GGCTCCTCCTCTCACGAAGAGGACGAGGAGGGCCCATACTACAGCGCACTGTCAGATGTA
  GAAATCCCTGAAAATCCTGAGGCATATCTTAAAATGACCACAAAAACTTTGAAAGCGTCT
  TCTGGTAAATCCATTTCGGATGGCCACTCGTGGCATGTTCCCGACAGCCCTTCCTGTCCC
  GAGCATCACTACAAGCAAATGGAAGGTGACAGGAATGTTCCACCTGTTCCCCCTGCGTCC
  AGCACCCCTTATAAACCACCCTATGGAAAGCTACTATTACCTCCAGGCACGGATGGTGGC
  AAAGAAGGCCCGCGAGTCCTGAATGGCAACCCACAGCAGGAAGACGGGGGACTGGCCGGT
  ATCACAGAGCAGCAGTCAGGTGCCTTCGACAGATGGGAGATGATTCAAGCACAGGAGCTT
  CACAATAAGCTCAAAATAAAACAAAATTTGCAACAGCTGAACTCTGATATCAGCGCCATC
  ACTACTTGGCTGAAAAAAACTGAAGCAGAGCTGGAAATGTTAAAGATGGCAAAGCCTCCC
  TCTGATATCCAGGAAATAGAACTGAGAGTGAAGAGACTGCAGGAGATACTGAAAGCCTTT
  GACACTTACAAGGCATTAGTGGTCTCTGTCAACGTGAGCAGCAAGGAATTTCTGCAAACC
  GAGAGCCCCGAATCCACAGAGCTCCAAAGTAGACTCCGCCAGCTGAGCCTGCTCTGGGAA
  GCAGCACAGGGCGCAGTGGACAGCTGGAGAGGGGGCTTACGACAGTCGCTCATGCAGTGC
  CAGGGCTCTAAGACACGGCCGCGCTCTGATGTGTTGTTTTTTAAGGACTTCCACCAGTTG
  AGTCAAAATCTGCTGCTGTGGTTAGCGAGTGCCAAGAACCGGAGGCAGAAGGCTCATGTC
  ACCGATCCAAAGGCAGACCCCCGGGCTCTCCTAGAGTGTCGGAGGGAACTAATGCAACTG
  GAAAAGGAGCTGGTAGAACGTCAACCTCAAGTGGACATGTTACAGGAGATTTCAAACAGC
  CTTCTCATTAAGGGACATGGAGAAGACTGTATTGAAGCTGAAGAAAAGGTGCATGTTATT
  GAGAAGAAACTCAAACAGTTACGGGAGCAAGTGTCCCAAGATTTAATGGCCTTGCAGGGA
  ACCCAGAACCCAGCCTCACCCCTGCCCAGCTTCGACGAGGTAGACTCGGGGGACCAGCCT
  CCTGCAACATCCGTGCCAGCTCCCCGAGCAAAGNAGTTCAGAGCAGTGAGAACTACAGAA
  GGCGAGGAGGAGACAGAGAGCAGGGTCCCCGGCAGCACACGGCCACAGCGCTCCTTCCTC
  TCAAGGGTGGTCCGGGCAGCCCTACCCCTGCAGCTGCTCCTCCTGCTGCTGCTGCTCCTG
  GCCTGCCTGCTGCCCTCCTCCGAAGAAGACTACAGCTGCACTCAGGCCAACAACTTTGCC
  CGGTCCTTTTACCCCATGCTGAGGTACACCAATGGGCCACCCCCCACATAG
  
  Clone variation with respect to NM_182913.2
  1414 c=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182913 unedited
  CAGACTTTTCTATAGGGCGGCACGCGCATTCGGCACGAGGGTGGTTTAGGGCTTGGAAGA
  TGAAAAGGAGGCCTCTGAGAATGAAACAGACATGGAAGACCCCAGAGAAATCCAGACTGA
  TTCTTGGCGTAAACGGGGAGAGAGCGAGGAACCGTCATCTCCTCAGTCCCTGTGTCATCT
  AGTGGCCCCAGGGCACGAGCGGTCTGGCTGCGAGACCCCTGTCAGCGTGGACTCCATCCC
  CCTGGAGTGGGACCACACAGGCGACGTGGGGGGCTCCTCCTCTCACGAAGAGGACGAGGA
  GGGCCCATACTACAGCGCACTGTCAGATGTAGAAATCCCTGAAAATCCTGAGGCATATCT
  TAAAATGACCACAAAAACTTTGAAAGCGTCTTCTGGTAAATCCATTTCGGATGGCCACTC
  GTGGCATGTTCCCGACAGCCCTTCCTGTCCCGAGCATCACTACAAGCAAATGGAAGGTGA
  CAGGAATGTTCCACCTGTTCCCCCTGCGTCCAGCACCCCTTATAAACCACCCTATGGAAA
  GCTACTATTACCTCCAGGCACGGATGGTGGCAAAGAAGGCCCGCGAGTCCTGAATGGCAA
  CCCACAGCAGGAAGACGGNGGACTGGCCGGTATCACAGAGCAGCAGTCAGGTGCCTTCGA
  CAGATGGGGAGATGATTCAAGCACAGGAGCTTCACAATAAGCTCANAATAAAACAAAATT
  CTGCACAGCTGAACTCTGATATCAGCGCCATCACTACTTGGGCTGAANAAAACTGAAGCA
  GAGCTGGGAATGGCTTAAGATGGCAAAGCCTCCCTCTGATATCCAGGAATAGATCTGAAA
  GTGAAGAGACTGCAGGAGATACTGGAAGCCCTTGACACTTACAGGACTTTANTGGGTCTC
  TGCCAACGCGAGCAGCNAGGGAATTCTGCAAACCGAGAGGCCCGNATCACAGAGCTNCAA
  ATANACTCCGCCAGCTGACCTGCTTTGGAATCAACCAGGCCCCATGGCACCTGGAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_182913
• ORF Size: 1671 bp
• Insert Size: 2550
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_182913.1, NP_878917.1
• RefSeq Size: 2712
• RefSeq ORF: 1671
• Locus ID: 23224
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (4) is shorter at the N-terminus compared to isoform 5. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.