alpha Glucosidase II (GANAB) (NM_198334) Human Untagged Clone

CAT#: SC107856

GANAB (untagged)-Human glucosidase, alpha, neutral AB (GANAB), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GANAB
• Synonyms: G2AN; GIIA; GLUII; PKD3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107856 sequence for NM_198334 edited (data generated by NextGen Sequencing)
  ATGGCGGCGGTAGCGGCAGTGGCGGCGCGTAGGAGGCGGTCTTGGGCGTCTTTGGTACTG
  GCTTTTTTAGGGGTCTGCCTGGGGATTACCCTTGCTGTGGATAGAAGCAACTTTAAGACC
  TGTGAAGAGAGTTCTTTCTGCAAGCGACAGAGAAGCATACGGCCAGGCCTCTCTCCATAC
  CGAGCCTTGCTGGACTCTCTACAGCTTGGTCCTGATTCCCTCACGGTCCATCTGATCCAT
  GAGGTCACCAAGGTGTTGCTGGTGCTAGAGCTTCAGGGGCTTCAAAAGAACATGACTCGG
  TTCAGGATTGATGAGCTGGAGCCTCGGCGACCCCGATACCGTGTACCAGATGTTTTGGTG
  GCTGATCCACCAATAGCCCGGCTTTCTGTCTCTGGTCGTGATGAGAACAGTGTGGAGTTA
  ACCATGGCTGAGGGACCCTACAAGATCATCTTGACAGCACGGCCATTCCGCCTTGACCTA
  CTAGAGGACCGAAGTCTTTTGCTTAGTGTCAATGCCCGAGGACTCTTGGAGTTTGAGCAT
  CAGAGGGCCCCTAGGGTCTCGCAAGGATCAAAAGACCCAGCTGAGGGCGATGGGGCCCAG
  CCTGAGGAAACACCCAGGGATGGCGACAAGCCAGAGGAGACTCAGGGGAAGGCAGAGAAA
  GATGAGCCAGGAGCCTGGGAGGAGACATTCAAAACTCACTCTGACAGCAAGCCGTATGGC
  CCCATGTCTGTGGGTTTGGACTTCTCTCTGCCAGGCATGGAGCATGTCTATGGGATCCCT
  GAGCATGCAGACAACCTGAGGCTGAAGGTCACTGAGGGTGGGGAGCCATATCGCCTCTAC
  AATTTGGATGTGTTCCAGTATGAGCTGTACAACCCAATGGCCTTGTATGGGTCTGTGCCT
  GTGCTCCTGGCACACAACCCTCATCGCGACTTGGGCATCTTCTGGCTCAATGCTGCAGAG
  ACCTGGGTTGATATATCTTCCAACACTGCCGGGAAGACCCTGTTTGGGAAGATGATGGAC
  TACCTGCAGGGCTCTGGGGAGACCCCACAGACAGATGTTCGCTGGATGTCAGAGACTGGC
  ATCATTGACGTCTTCCTGCTGCTGGGGCCCTCCATCTCTGATGTTTTCCGGCAATATGCT
  AGTCTCACAGGAACCCAGGCGTTGCCCCCACTCTTCTCCCTCGGCTACCACCAGAGCCGT
  TGGAACTACCGGGACGAGGCTGATGTGCTGGAAGTGGATCAGGGCTTTGATGATCACAAC
  CTGCCCTGTGATGTCATCTGGCTAGACATTGAACATGCTGATGGCAAGCGGTATTTCACC
  TGGGACCCCAGTCGCTTCCCTCAGCCCCGCACCATGCTTGAGCGCTTGGCTTCTAAGAGG
  CGGAAGCTGGTGGCCATCGTAGACCCCCACATCAAGGTGGACTCCGGCTACCGAGTTCAC
  GAGGAGCTGCGGAACCTGGGGCTGTATGTTAAAACCCGGGATGGCTCTGACTATGAGGGC
  TGGTGCTGGCCAGGCTCAGCTGGTTACCCTGACTTCACTAATCCCACGATGAGGGCCTGG
  TGGGCTAACATGTTCAGCTATGACAATTATGAGGGCTCAGCTCCCAACCTCTTTGTCTGG
  AATGACATGAACGAACCATCTGTGTTCAATGGTCCTGAGGTCACCATGCTCAAGGATGCC
  CAGCATTATGGGGGCTGGGAGCACCGGGATGTGCATAACATCTATGGCCTTTATGTGCAC
  ATGGCGACTGCTGATGGGCTGAGACAGCGCTCTGGGGGCATGGAACGCCCCTTTGTCCTG
  GCCAGGGCCTTCTTCGCTGGCTCCCAGCGCTTTGGAGCCGTGTGGACAGGGGACAACACT
  GCCGAGTGGGACCATTTGAAGATCTCTATTCCTATGTGTCTCAGCTTGGGGCTGGTGGGA
  CTTTCCTTCTGTGGGGCGGATGTGGGTGGCTTCTTCAAAAACCCAGAGCCAGAGCTGCTT
  GTGCGCTGGTACCAGATGGGTGCTTACCAGCCATTCTTCCGGGCACATGCCCACTTGGAC
  ACTGGGCGACGAGAGCCATGGCTGTTACCATCTCAGCACAATGATATAATCCGAGATGCC
  TTGGGCCAGCGATATTCTTTGCTGCCCTTCTGGTACACCCTCTTATATCAGGCCCATCGG
  GAAGGCATTCCTGTCATGAGGCCCCTGTGGGTGCAGTACCCTCAGGATGTGACTACCTTC
  AATATAGATGATCAGTACTTGCTTGGGGATGCGTTGCTGGTTCACCCTGTATCAGACTCT
  GGAGCCCATGGTGTCCAGGTCTATCTGCCTGGCCAAGGGGAGGTGTGGTATGACATTCAA
  AGCTACCAGAAGCATCATGGTCCCCAGACCCTGTACCTGCCTGTAACTCTAAGCAGTATC
  CCTGTGTTCCAGCGTGGAGGGACAATCGTGCCTCGATGGATGCGAGTGCGGCGGTCTTCA
  GAATGTATGAAGGATGACCCCATCACTCTCTTTGTTGCACTTAGCCCTCAGGGTACAGCT
  CAAGGAGAGCTCTTTCTGGATGATGGGCACACGTTCAACTATCAGACTCGCCAAGAGTTC
  CTGCTGCGTCGATTCTCATTCTCTGGCAACACCCTTGTCTCCAGCTCAGCAGACCCTGAA
  GGACACTTTGAGACACCAATCTGGATTGAGCGGGTGGTGATAATAGGGGCTGGAAAGCCA
  GCAGCTGTGGTACTCCAGACAAAAGGATCTCCAGAAAGCCGCCTGTCCTTCCAGCATGAC
  CCTGAGACCTCTGTGTTGGTCCTGCGCAAGCCTGGCATCAATGTGGCATCTGATTGGAGT
  ATTCACCTGCGATAA
  
  Clone variation with respect to NM_198334.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198334 unedited
  AAAACTTGATTTGTATACGACTTACTATAGGCGGCCGCGATTCGGCACGAGGAGCAAACT
  CTGCACAAAATGGCGGCGGTAGCGGCAGTGGCGGCGCGTAGGAGGCGGTCTTGGGCGTCT
  TTGGTACTGGCTTTTTTAGGGGTCTGCCTGGGGATTACCCTTGCTGTGGATAGAAGCAAC
  TTTAAGACCTGTGAAGAGAGTTCTTTCTGCAAGCGACAGAGAAGCATACGGCCAGGCCTC
  TCTCCATACCGAGCCTTGCTGGACTCTCTACAGCTTGGTCCTGATTCCCTCACGGTCCAT
  CTGATCCATGAGGTCACCAAGGTGTTGCTGGTGCTAGAGCTTCAGGGGCTTCAAAAGAAC
  ATGACTCGGTTCAGGATTGATGAGCTGGAGCCTCGGCGACCCCGATACCGTGTACCAGAT
  GTTTTGGTGGCTGATCCACCAATAGCCCGGCTTTCTGTCTCTGGTCGTGATGAGAACAGT
  GTGGAGTTAACCATGGCTGAGGGACCCTACAAGATCATCTTGACAGCACGGCCATTCCGC
  CTTGACCTACTAGAGGACCGAAGTCTTTTGCTTAGTGTCAATGCCCGAGGACTCTTGGAG
  TTTGAGCATCAGAGGGCCCCTAGGGTCTCGCAAGGATCAAAAGACCCAGCTGAGGGCGAT
  GGGGCCCAGCCTGAGGAAACACCCAGGGATGGCGACAAGCCAGAGGAGACTCAGGGGAAG
  GCAGAGAAAGATGAGCCAGGAGCCTGNGAGGAGACATTCAAAACTCACTTCTGACAGCAG
  CCGTATGGCCCCATGTCTGTGGGTTTGGACTTCTCTCTGCCAGGCATGGAGCATGTCTAT
  GGGATCCCTGAGCATGCAGACCACCTGAGGCTGAAGGTCACTNGAGGNTGGGGAGCCATA
  TC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_198334 unedited
  CCGCGGCCGCAATTTAGAGTCGAGTTTTTTTTCTTTTTTTTTTTTATGGGTTATCCCTTT
  ATTGTTTCTCCTTTGATCAAAACGTGTCACAGCTGGGAACCAAGAGGAAGTAAAAAAAAT
  ACCCACAAATATTCCCCGACTCCCCATTAGTCCTCCCCCAACCCCCCACCCAGGGCTTCC
  AGCCAACCCCGAGCACACATGATCATCTCCCCCCACCCTCAGGCTTCTCCTAGCAATAAA
  TACAGGTGACCATGATTCACTGAAACCACAACTGATTTCTCCATCTTAAGTGCCCCTCAA
  AGGGGACAAGAAGGGGGCAAAAGAAGTTTAATGCGCATCCCCTAAGAGGTGTGGAAACGT
  CTTTCTGCCGAGGGACAGAGGAGGTAGAACTGCCCCTCTAAGAATTGCAGCAGCTCTACA
  AGGAATCGGGGAGAGGAAAAGGGTAGAATGAGAGGGAAAAGGATGTTCTTTAGCAACCTC
  ACTCCTTTGATCCATTCATCCTGTCCGGGGTAAGGGGTGGTCCCAGTGTATCGGTGGGGC
  ATAAAAAGGGGAGTAAAGCCTGGAGGAAGAAATGAAAGGTGGGAGAGCAATCTGGTGGGA
  GGGAAGGGGAAAAGGAGCCCTAACTCATTGCCCTCATCTTCTTCCAAGAAGTGGCATCAA
  CATACAAGAGGCATGAATGGATAGACTCTGGGGGGGAGTCAGGGCTCCTAAATAAGGGGA
  AGAGAAGGNGCGACAAGGGCCCTGTGGGTTNCTGGNNTGTCGTAGTGAATGTGCTCCAGN
  TAGAGCAACAGGNATGTGGGGGAATGAAGGAAAGAGTNNGTATCATGGAGTGGGAGAGTG
  NAGGAGATCACNAGAGGGATTNNGAGCCCANGGTCAGCCNTCTCATNCTGCCCAATGGTG
  GCAGAATCTGGGNTCTANACANCATAAGTGAGTCTGGGGGAGGGCCCGACTNNCAGGCAG
  AAGAANGATATCTNTCANACTTATGGCTCCCTTNCCTNCCCNTAACCAAACATCCNTGGG
  NNTTNCGCAGGTGNAACTCNCATCAGAGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_198334
• ORF Size: 2835 bp
• Insert Size: 4070
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_198334.1, NP_938148.1
• RefSeq Size: 3887
• RefSeq ORF: 2835
• Locus ID: 23193
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
  Transcript Variant: This variant (2) lacks an in-frame exon, compared to variant 3. The resulting isoform (2, also known as the alpha1 isoform) lacks an internal segment, compared to isoform 3.