HSD17B7 (NM_016371) Human Untagged Clone

CAT#: SC108681

HSD17B7 (untagged)-Human hydroxysteroid (17-beta) dehydrogenase 7 (HSD17B7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HSD17B7
• Synonyms: PRAP; SDR37C1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108681 sequence for NM_016371 edited (data generated by NextGen Sequencing)
  ATGCGAAAGGTGGTTTTGATCACCGGGGCTAGCAGTGGCATTGGCCTGGCCCTCTGCAAG
  CGGCTGCTGGCGGAAGATGATGAGCTTCATCTGTGTTTGGCGTGCAGGAACATGAGCAAG
  GCAGAAGCTGTCTGTGCTGCTCTGCTGGCCTCTCACCCCACTGCTGAGGTCACCATTGTC
  CAGGTGGATGTCAGCAACCTGCAGTCGGTCTTCCGGGCCTCCAAGGAACTTAAGCAAAGG
  TTTCAGAGATTAGACTGTATATATCTAAATGCTGGGATCATGCCTAATCCACAACTAAAT
  ATCAAAGCACTTTTCTTTGGCCTCTTTTCAAGAAAAGTGATTCATATGTTCTCCACAGCT
  GAAGGCCTGCTGACCCAGGGTGATAAGATCACTGCTGATGGACTTCAGGAGGTGTTTGAG
  ACCAATGTCTTTGGCCATTTTATCCTGATTCGGGAACTGGAGCCTCTCCTCTGTCACAGT
  GACAATCCATCTCAGCTCATCTGGACATCATCTCGCAGTGCAAGGAAATCTAATTTCAGC
  CTCGAGGACTTCCAGCACAGCAAAGGCAAGGAACCCTACAGCTCTTCCAAATATGCCACT
  GACCCTTTGAGTGTGGCTTTGAACAGGAACTTCAACCAGCAGGGTCTCTATTCCAATGTG
  GCCTGTCCAGGTACAGCATTGACCAATTTGACATATGGAATTCTGCCTCCGTTTATATGG
  ACGCTGTTGATGCCGGCAATATTGCTACTTCGCTTTTTTGCAAATGCATTCACTTTGACA
  CCATATAATGGAACAGAAGCTCTGGTATGGCTTTTCCACCAAAAGCCTGAATCTCTCAAT
  CCTCTGATCAAATATCTGAGTGCCACCACTGGCTTTGGAAGAAATTACATTATGACCCAG
  AAGATGGACCTAGATGAAGACACTGCTGAAAAATTTTATCAAAAGTTACTGGAACTGGAA
  AAGCACATTAGGGTCACTATTCAAAAAACAGATAATCAGGCCAGGCTCAGTGGCTCATGC
  CTATAA
  
  Clone variation with respect to NM_016371.2
  605 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016371 unedited
  GGCTAAGGGTTNNGAAANCNNCGCTGGGGGTGGCGGAAAACCCCTTCGCACGAGGCAGCG
  GTGGCTTTTGCTTCACTGCTTGGAAGTGTGAGTGCGCGAAGATGCGAAAGGTGGTTTTGA
  TCACCGGGGCTAGCAGTGGCATTGGCCTGGCCCTCTGCAAGCGGCTGCTGGCGGAAGATG
  ATGAGCTTCATCTGTGTTTGGCGTGCAGGAACATGTCCTCGTCAGAAGCTGTCTGTGCTG
  CTCTGCTGGCCTCTCACCCCACTGCTGAGGTCACCATTGTCCAGGTGGATGTCAGCAACC
  TGCAGTCGGTCTTCCGGGCCTCCAAGGAACTTAAGCAAAGGTTTCAGAGATTAGACTGTA
  TATATCTAAATGCTGGGATCATGCCTAATCCACAACTAAATATCAAAGCACTTTTCTTTG
  GCCTCTTTTCAAGAAAAGTGATTCATATGTTCTCCACAGCTGAAGGCCTGCTGACCCAGG
  GTGATAAGATCACTGCTGATGGACTTCAGGAGGTGTTTGAGACCAATGTCTTTGGCCATT
  TTATCCTGATTCGGGAACTGGAGCCTCTCCTCTGTCACAGTGACAATCCATCTCAGCTCA
  TCTGGACATCATCTCGCAGTGCAAGGAAATCTAATTTCAGCCTCGAGGACTTCCAGCACA
  GCAAAGGCAAAGAACCCTACAGCTCTTCCAAATATGCCACTGACCCTTTGAGTGTGGCTT
  TGAACAGGAACTTCAACCAGCAGGGTCTCTATTCCAATGTGGCCTGTCCAGGTACAGCAT
  TGACCATTTTGACATATGGAATTCTGCCTCCGTTTATATGGACGCTGTTGGATGCCGGCA
  TATTGCTACTCCGCTCTTTTGCAAATGCATTCCCTTTGGCCCCTATTATGGAACAGAAGC
  TCTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016371 unedited
  AGAACCGAAGCCCGCNCTTCTAGNAGACGAGTTTTTTCCCCTTTTTTCTTTGCTAGTCTC
  ATAGTCTTATTACAAATGCCTATTATCCAACTCACTAGAAATCCATGTACCCCACAAGCA
  CAGAAGGTATGCAATGTTCCAGAGTGCCATTGCCAGCTCTGGTTTTATATATATATTAAA
  TATATACATATTTTGAGACAGGGTCTCGCTGTCACCCAGGCTGGAGTGCAGTGGCACAAT
  CTCAGCTCACTGCAACCTCTGCCTCCCAACCTCAAGAGATCCTCCAACCTCATCCTTCTG
  AGTACCTGGGACTACATGCGCATGCCACCACACCCAGCTATTATTTTTATTACTTTTTGA
  AGAGACAAGGGCTCACTATGTTTATCAGGCTGGTCTTGAACTCCTGGACTAAAGAGATCC
  TTCTGCCTTGGCCTACCAAAGCGCCGGAATTATAGGCATGAGCCACTGACCCTGGCCTGA
  TTATCTGTTTTTTGAATACCGACCCTAATGCGCTTTTACAGCCCCAGCAACCTTTTGATA
  AAATTCTTGAACAGCGACTATATCTAGGCCCATCTTCTGGGCCATAATGCAATTCCTTCC
  AAAGACAGTGGTGGATCTCACATTTTGACCAGAGGATTGAAAGATTCACGCCCTAGGAGG
  AAAACCCTACCAGAGCTCTTGTCCCTTATATGGCGCAAAGCGAACTGCCTTCTCGCCAAA
  ACCCAACACCATATTGCCGGGCCTCACCGCGCTCTTTAACGGGGCAGACTTCATATGCAA
  ATTGGTCATGCTGACCTGCCAGGCCCATTGGATAAAACCCCGCTGGTGAATTCCCGTCCA
  ACCCCCTCAAGGGTCACGCCCTTTCGAAAACCGACGGCCCTCGCCTTGTGGCTGAAGCCC
  CAGCCGAATAAATTCCTGCCTGCAAGATCCCCAGACCTGAAGCTGCCCTGGGCAAAGAAG
  GCCCCCCCCCATCGATAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016371
• ORF Size: 1026 bp
• Insert Size: 1540
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016371.2, NP_057455.1
• RefSeq Size: 1533
• RefSeq ORF: 1026
• Locus ID: 51478
• Domains: adh_short
• Protein Families: Druggable Genome
• Protein Pathways: Androgen and estrogen metabolism, Metabolic pathways, Steroid biosynthesis
• Gene Summary: HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]). [supplied by OMIM, May 2010]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).