Transportin 1 (TNPO1) (NM_153188) Human Untagged Clone

CAT#: SC109373

TNPO1 (untagged)-Human transportin 1 (TNPO1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TNPO1
• Synonyms: IPO2; KPNB2; MIP; MIP1; TRN
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109373 sequence for NM_153188 edited (data generated by NextGen Sequencing)
  ATGGAGTATGAGTGGAAACCTGACGAGCAAGGGCTTCAGCAAATCCTGCAGCTGTTGAAG
  GAGTCCCAGTCCCCAGACACCACCATCCAGAGAACCGTGCAACAAAAACTGGAACAACTT
  AATCAGTATCCAGACTTTAACAACTACTTGATTTTTGTTCTTACAAAATTAAAATCTGAA
  GATGAACCCACAAGATCATTGAGTGGTCTTATCTTGAAGAATAATGTGAAAGCACACTTT
  CAGAACTTCCCAAATGGTGTAACAGACTTTATTAAAAGTGAATGTTTAAATAATATTGGT
  GACTCCTCTCCTCTGATTAGAGCCACTGTTGGTATTTTGATCACAACTATAGCCTCCAAG
  GGAGAATTGCAGAATTGGCCTGACCTCTTACCAAAACTCTGTAGCCTGTTGGATTCTGAA
  GATTATAATACCTGTGAGGGAGCATTTGGTGCCCTTCAGAAGATTTGTGAAGATTCTGCT
  GAGATTTTAGACAGTGATGTTTTAGATCGTCCTCTCAACATCATGATTCCCAAATTTTTA
  CAGTTCTTCAAGCATAGTAGTCCAAAAATAAGGTCTCACGCTGTTGCATGTGTCAATCAG
  TTTATCATCAGTAGGACTCAAGCTCTAATGTTGCACATTGATTCTTTTATTGAGAATCTC
  TTTGCATTAGCTGGTGATGAAGAACCAGAGGTACGGAAAAATGTGTGCCGAGCACTTGTG
  ATGTTGCTCGAAGTTCGAATGGATCGCCTGCTTCCTCACATGCATAATATAGTTGAGTAC
  ATGCTACAGAGGACTCAAGATCAAGATGAAAATGTGGCTTTAGAAGCCTGTGAATTTTGG
  CTAACTTTAGCTGAACAGCCAATATGCAAAGATGTACTCGTAAGGCATCTTCCTAAGTTG
  ATTCCTGTGTTAGTGAATGGCATGAAGTACTCAGACATAGATATTATCCTACTTAAGGGT
  GATGTTGAAGAAGACGAAACGATTCCTGATAGTGAACAGGATATACGGCCACGTTTTCAC
  CGATCGAGGACGGTGGCTCAGCAGCATGATGAAGATGGAATTGAAGAGGAAGATGATGAT
  GATGATGAAATTGATGATGATGATACAATTTCTGACTGGAATCTAAGAAAATGTTCTGCT
  GCTGCCCTGGATGTTCTTGCAAATGTGTATCGTGATGAACTGCTGCCACATATTTTGCCC
  CTTTTGAAAGAATTACTTTTTCATCATGAATGGGTTGTTAAAGAATCAGGCATTTTGGTT
  TTAGGAGCAATTGCTGAAGGTTGCATGCAGGGCATGATTCCATACTTGCCTGAGCTTATT
  CCTCACCTTATTCAGTGCCTCTCTGATAAAAAGGCTCTTGTGCGTTCCATAACATGCTGG
  ACTCTTAGCCGCTATGCACACTGGGTGGTCAGCCAGCCGCCAGACACGTACCTGAAGCCA
  TTAATGACAGAATTGCTAAAGCGCATCCTGGATAGCAACAAGAGAGTACAAGAAGCTGCC
  TGCAGTGCCTTTGCTACCCTAGAAGAGGAGGCTTGTACAGAACTTGTTCCTTACCTTGCT
  TATATACTTGATACCCTGGTCTTTGCATTTAGTAAATACCAGCATAAGAACCTGCTCATT
  CTTTACGATGCCATAGGAACATTAGCAGATTCAGTAGGACATCATTTAAACAAACCAGAA
  TATATTCAGATGCTAATGCCTCCACTGATCCAGAAATGGAACATGTTAAAGGATGAAGAT
  AAAGATCTCTTCCCTTTACTTGAGTGCCTATCTTCAGTTGCCACAGCACTGCAGTCTGGA
  TTCCTTCCGTACTGTGAACCTGTGTATCAGCGTTGTGTAAACCTAGTACAGAAGACTCTT
  GCACAAGCCATGCTAAACAATGCTCAACCAGATCAATATGAAGCTCCAGATAAAGATTTT
  ATGATAGTGGCTCTTGATTTACTGAGTGGCCTGGCTGAAGGACTTGGAGGCAACATTGAA
  CAGCTGGTAGCCCGAAGTAACATCCTGACACTAATGTATCAGTGCATGCAGGATAAAATG
  CCAGAAGTTCGACAGAGTTCTTTTGCCCTGTTAGGTGACCTCACAAAAGCTTGCTTTCAG
  CATGTTAAGCCTTGTATAGCTGATTTCATGCCAATATTGGGAACCAACCTAAATCCAGAA
  TTCATTTCAGTCTGCAACAATGCCACATGGGCAATTGGAGAAATCTCCATTCAAATGGGT
  ATAGAGATGCAGCCTTATATTCCTATGGTGTTGCACCAGCTTGTAGAAATCATTAACAGA
  CCCAACACACCAAAGACGTTGTTAGAGAATACAGCAATAACAATTGGTCGTCTTGGTTAC
  GTTTGTCCTCAAGAGGTGGCCCCCATGCTACAGCAGTTTATAAGACCCTGGTGCACCTCT
  CTGAGAAACATAAGAGACAATGAGGAAAAGGATTCAGCATTCCGTGGAATTTGTACCATG
  ATCAGTGTGAATCCCAGTGGCGTAATCCAAGATTTTATATTTTTTTGTGATGCCGTTGCA
  TCATGGATTAACCCAAAAGATGATCTCAGAGACATGTTCTGTAAGATCCTTCATGGATTT
  AAAAATCAAGTTGGCGATGAAAATTGGAGGCGTTTCTCTGACCAGTTTCCTCTTCCCTTA
  AAAGAGCGTCTTGCAGCTTTTTATGGTGTTTAA
  
  Clone variation with respect to NM_153188.2
  1473 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153188 unedited
  GGGGGGGGGGGGGAANNNNTTTNTTTAAANNNNGTTTTACCCCCGCCCGTTGCCNCATTG
  GGCGGTAGGCGTGTACGGTGGGNAGTCTATATAAGCAGAGCTCATTTAGGTGACACTATA
  GAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGGGCGGCCGGG
  CTGCCAGGAGCAGTTCCGCCGGGTTTCACTGTCCGTGACTTCCTTCGGGGCACCTCAGGC
  AGCAAACCAAGATGGAGTATGAGTGGAAACCTGACGAGCAAGGGCTTCAGCAAATCCTGC
  AGCTGTTGAAGGAGTCCCAGTCCCCAGACACCACCATCCAGAGAACCGTGCAACAAAAAC
  TGGAACAACTTAATCAGTATCCAGACTTTAACAACTACTTGATTTTTGTTCTTACAAAAT
  TAAAATCTGAAGATGAACCCACAAGATCATTGAGTGGTCTTATCTTGAAGAATAATGTGA
  AAGCACACTTTCAGAACTTCCCAAATGGTGTAACAGACTTTATTAAAAGTGAATGTTTAA
  ATAATATTGGTGACTCCTCTCCTCTGATTAGAGCCACTGTTGGTATTTTGATCACAACTA
  TAGCCTCCAAGGGAGAATTGCAGAATTGGCCTGACCTCTTACCAAAACTCTGTAGCCTGT
  TGGATTCTGAAGATTATAATACCTGTGAGGGAGCATTTGGTGCCCTTCAGAAGATTTGTG
  AAGATTCTGCTGAGATTTTAGACAGTGATGTTTTAGATCGTCCTCTCAACATCATGATTC
  CCAAATTTTTACAGTTCTTCAAGCATAGTAGTCCAAAATAAGGTCTCACGCTGTTGCATG
  TGTCAAATCAGTTATCATCAGTAGGACTCAAGCTCTAATGTNGCACATTGATTCTTTTAT
  TGAGAATCTCTTTGCATTAGCTGGTGATGAAGAACCAGAGGTACGGAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_153188 unedited
  GCACTACTATGTACGTGGCCGCTTCNTANATCGAGTTTTTTTTTTTTTTTTTTGCTTCTT
  CACATCCACTGGCGGATTGTAACTGGGAGAATATTTCCACCCACAAAGGCTCCAGATGTT
  AAAACGTTTCCCAACATCGACTTAATACAGTGACGGCAACACCTCCCTCCCGCCCCTCCC
  AGTAGGGTTGGGATTGTACTGTATTCCCTACTGGTTTACCCTTCCCCCCTGTAAAGGGTA
  ACATTTTCCCTGGGTGCAGAGGCTCCCTTATAGTCTCCAAGACTGAAGGACCCCTAATTT
  TGGGACTGCAGCTTAAGTGTATTAGATTAAACACCATAAAAAGCTGCAAGACGCTCTTTT
  AAGGGAAGAGGAAACTGGTCAGAGAAACGCCTCCAATTTTCATCGCCAACTTGATTTTTA
  AATCCATGAAGGATCTTACAGAACATGTCTCTGAGATCATCTTTTGGGTTAATCCATGAT
  GCAACGGCATCACAAAAAAATATAAAATCTTGGATTACGCCACTGGGATTCACACTGATC
  ATGGTACAAATTCCACGGAATGCTGAATCCTTTTCCTCATTGTCTCTTATGTTTCTCAGA
  GAGGTGCACCAAGGTCTTATAAACTGCTGTAGCATGGGGGCCACCTCTTGAAGACAAACG
  TAACCAAGACGACCAAATGGTATTGCTGGATTCTCTAACACGTCTTAGGTGGGTTGGGTC
  TGTTAATGATTTCTACAAGCTGGGGCACACCCTAAGAATATAAAGGCTGCATTTCTTTTC
  CCCTTTGAATGGGGATTTCTCCATTGGCCCTGTGGCATTGTTGCAGACGGAAAGGAATCT
  GGGATTTAGGTTGGGTCCCCAATTTGGCTGGAAACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153188
• ORF Size: 2673 bp
• Insert Size: 3200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_153188.1, NP_694858.1
• RefSeq Size: 3026
• RefSeq ORF: 2673
• Locus ID: 3842
• Domains: Armadillo_seg, IBN_NT
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins. [provided by RefSeq, Jun 2018]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Variants 2, 3, and 4 all encode the same isoform (2).