SRC (NM_198291) Human Untagged Clone

CAT#: SC109795

SRC (untagged)-Human v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 2


  "NM_198291" in other vectors (6)

Reconstitution Protocol

USD 540.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SRC
Synonyms ASV; c-SRC; p60-Src; SRC1; THC6
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_198291 edited
CATCGAGGTTTTGAGAGGCTAACTCTCCCAAAAAGGACCATGGGTAGCAACAAGAGCAAG
CCCAAGGATGCCAGCCAGCGGCGCCGCAGCCTGGAGCCCGCCGAGAACGTGCACGGCGCT
GGCGGGGGCGCTTTCCCCGCCTCGCAGACCCCCAGCAAGCCAGCCTCGGCCGACGGCCAC
CGCGGCCCCAGCGCGGCCTTCGCCCCCGCGGCCGCCGAGCCCAAGCTGTTCGGAGGCTTC
AACTCCTCGGACACCGTCACCTCCCCGCAGAGGGCGGGCCCGCTGGCCGGTGGAGTGACC
ACCTTTGTGGCCCTCTATGACTATGAGTCTAGGACGGAGACAGACCTGTCCTTCAAGAAA
GGCGAGCGGCTCCAGATTGTCAACAACACAGAGGGAGACTGGTGGCTGGCCCACTCGCTC
AGCACAGGACAGACAGGCTACATCCCCAGCAACTACGTGGCGCCCTCCGACTCCATCCAG
GCTGAGGAGTGGTATTTTGGCAAGATCACCAGACGGGAGTCAGAGCGGTTACTGCTCAAT
GCAGAGAACCCGAGAGGGACCTTCCTCGTGCGAGAAAGTGAGACCACGAAAGGTGCCTAC
TGCCTCTCAGTGTCTGACTTCGACAACGCCAAGGGCCTCAACGTGAAGCACTACAAGATC
CGCAAGCTGGACAGCGGCGGCTTCTACATCACCTCCCGCACCCAGTTCAACAGCCTGCAG
CAGCTGGTGGCCTACTACTCCAAACACGCCGATGGCCTGTGCCACCGCCTCACCACCGTG
TGCCCCACGTCCAAGCCGCAGACTCAGGGCCTGGCCAAGGATGCCTGGGAGATCCCTCGG
GAGTCGCTGCGGCTGGAGGTCAAGCTGGGCCAGGGCTGCTTTGGCGAGGTGTGGATGGGG
ACCTGGAACGGTACCACCAGGGTGGCCATCAAAACCCTGAAGCCTGGCACGATGTCTCCA
GAGGCCTTCCTGCAGGAGGCCCAGGTCATGAAGAAGCTGAGGCATGAGAAGCTGGTGCAG
TTGTATGCTGTGGTTTCAGAGGAGCCCATTTACATCGTCACGGAGTACATGAGCAAGGGG
AGTTTGCTGGACTTTCTCAAGGGGGAGACAGGCAAGTACCTGCGGCTGCCTCAGCTGGTG
GACATGGCTGCTCAGATCGCCTCAGGCATGGCGTACGTGGAGCGGATGAACTACGTCCAC
CGGGACCTTCGTGCAGCCAACATCCTGGTGGGAGAGAACCTGGTGTGCAAAGTGGCCGAC
TTTGGGCTGGCTCGGCTCATTGAAGACAATGAGTACACGGCGCGGCAAGGTGCCAAATTC
CCCATCAAGTGGACGGCTCCAGAAGCTGCCCTCTATGGCCGCTTCACCATCAAGTCGGAC
GTGTGGTCCTTCGGGATCCTGCTGACTGAGCTCACCACAAAGGGACGGGTGCCCTACCCT
GGGATGGTGAACCGCGAGGTGCTGGACCAGGTGGAGCGGGGCTACCGGATGCCCTGCCCG
CCGGAGTGTCCCGAGTCCCTGCACGACCTCATGTGCCAGTGCTGGCGGAAGGAGCCTGAG
GAGCGGCCCACCTTCGAGTACCTGCAGGCCTTCCTGGAGGACTACTTCACGTCCACCGAG
CCCCAGTACCAGCCCGGGGAGAACCTCTAGGCACAGGCGGGCCCAGACCGGCTTCTCGGC
TTGGATCCTGGGCTGGGTGGCCCCTGTCTCGGGGCTTGCCCCACTCTGCCTGCCTGCTGT
TGGTCCTCTCTCTGTGGGGCTGAATTGCCAGGGGCGAGGCCCTTCCTCTTTGGTGGCATG
GAAGGGGCTTCTGGACCTAGGGTGGCCTGAGAGGGCGGTGGGTATGCGAGACCAGCACGG
TGACTCTGTCCAGCTCCCGCTGTGGCCGCACGCCTCTCCCTGCACTCCCTCCTGGAGCTC
TGTGGGTCTCTGGAAGAGGAACCAGGAGAAGGGCTGGGGCCGGGGCTGAGGGTGCCCTTT
TCCAGCCTCAGCCTACTCCGCTCACTGAACTCCTTCCCCACTTCTGTGCCACCCCCGGTC
TATGTCGAGAGCTGGCCAAAGAGCCTTTCCAAAGAGGAGCGATGGGCCCCTGGCCCCGCC
TGCCTGCCACCCTGCCCCTTGCCATCCATTCTGGAAACACCTGTAGGCAGAGGCTGCCGA
GACAGACCCTCTGCCGCTGCTTCCAGGCTGGGCAGCACAAGGCCTTGCCTGGCCTGATGA
TGGTGGGTGGGTGGGATGAGTACCCCCTCAAACCCTGCCCTCCTTAGACCTGAGGGACCC
TTCGAGATCATCACTTCCTTGCCCCCATTTCACCCATGGGGAGACAGTTGAGAGCGGGGA
TGTGACATGCCCAAGGCCACGGAGCAGTTCAGAGTGGAGGCGGGCTTGGAACCCGGTGCT
CCCTCTGTCATCCTCAGGAACCAACAATTCGTCGGAGGCATCATGGAAAGACTGGGACAG
CCCAGGAAACAAGGGGTCTGAGGATGCATTCGAGATGGCAGATTCCCACTGCCGCTGCCC
GCTCAGCCCAGCTGTTGGGAACAGCATGGAGGCAGATGTGGGGCTGAGCTGGGGAATCAG
GGTAAAAGGTGCAGGTGTGGAGAGAGAGGCTTCAATCGGCTTGTGGGTGATGTTTGACCT
TCAGAGCCAGCCGGCTATGAAAGGGAGCGAGCCCCTCGGCTCTGGAGGCAATCAAGCAGA
CATAGAAGAGCCAAGAGTCCAGGAGGCCCTGGTCCTGGCCTCCTTCCCCGTACTTTGTCC
CGTGGCATTTCAATTCCTGGCCCTGTTCTCCTCCCCAAGTCGGCACCCTTTAACTCATGA
GGAGGGAAAAGAGTGCCTAAGCGGGGGTGAAAGAGGACGTGTTACCCACTGCCATGCACC
AGGACTGGCTGTGTAACCTTGGGTGGCCCCTGCTGTCTCTCTGGGCTGCAGAGTCTGCCC
CACATGTGGCCATGGCCTCTGCAACTGCTCAGCTCTGGTCCAGGCCCTGTGGCAGGACAC
ACATGGTGAGCCTAGCCCTGGGACATCAGGAGACTGGGCTCTGGCTCTGTTCGGCCTTTG
GGTGTGTGGTGGATTCTCCCTGGGCCTCAGTGTGCCCATCTGTAAAGGGGCAGCTGACAG
TTTGTGGCATCTTGCCAAGGGTCCCTGTGTGTGTGTATGTGTGTGCATGTGTGCGTGTCT
CCATGTGCGTCCATATTTAACATGTAAAAATGTCCCCCCCGCTCCGTCCCCCAAACATGT
TGTACATTTCACCATGGCCCCCTCATCATAGCAATAACATTCCCACTGCCAGGGGTTCTT
GAGCCAGCCAGGCCCTGCCAGTGGGGAAGGAGGCCAAGCAGTGCCTGCCTATGAAATTTC
AACTTTTCCTTTCATACGTCTTTATTACCCAAGTCTTCTCCCGTCCATTCCAGTCAAATC
TGGGCTCACTCACCCCAGCGAGCTCTCAAATCCCTCTCCAACTGCCTAAGGCCCTTTGTG
TAAGGTGTCTTAATACTGTCCTTTTTTTTTTTTTAACAGTGTTTTGTAGATTTCAGATGA
CTATGCAGAGGCCTGGGGGACCCCTGGCTCTGGGCCGGGCCTGGGGCTCCGAAATTCCAA
GGCCCAGACTTGCGGGGGGTGGGGGGGTATCCAGAATTGGTTGTAAATACTTTGCATATT
GTCTGATTAAACACAAACAGACCTCAGAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_198291 unedited
NGGGAATTCAGTATTTGTTAAACGACTCACTATAGGCGGCCGCGAATTCGCACGAGCATC
GAGGTTTTGAGAGGCTAACTGCTCCCAAAAAGGACCATGGGTCAGCAACAAGAGCAAGCC
CAAGGATGCCAGCCAGCGGCGCCGCAGCCTGGAGCCCGCCGAGAACGTGCACGGCGCTGG
CGGGGGCGCTTTCCCCGCCTCGCAGACCCCCAGCAAGCCAGCCTCGGCCGACGGCCACCG
CGGCCCCAGCGCGGCCTTCGCCCCCGCGGCCGCCGAGCCCAAGCTGTTCGGAGGCTTCAA
CTCCTCGGACACCGTCACCTCCCCGCAGAGGGCGGGCCCGCTGGCCGGTGGAGTGACCAC
CTTTGTGGCCCTCTATGACTATGAGTCTAGGACGGAGACAGACCTGTCCTTCAAGAAAGG
CGAGCGGCTCCAGATTGTCAACAACACAGAGGGAGACTGGTGGCTGGCCCACTCGCTCAG
CACAGGACAGACAGGCTACATCCCCAGCAACTACGTGGCGCCCTCCGACTCCATCCAGGC
TGAGGAGTGGTATTTTGGCAAGATCACCAGACGGGAGTCAGAGCGGTTACTGCTCAATGC
AGAGAACCCGAGAGGGACCTTCCTCGTGCGAGAAAGTGAGACCACGAAAGGTGCCTACTG
CCTCTCAGTGTCTGACTTCGACAACGCCAAGGGCCTCAACGTGAAGCACTACAAGATCCG
CAAGCTGGACAGCGGCGGCTTCTACATCACCTCCCGCACCCAGTTCAACAGCCTGCAGCA
GCTGGTGGCCTACTACTCCAAACACGCCGATGGCCTGTGCCACCGCCTCACCACCGTGTG
CCCCACGTCCAAGCCGCAGAACTCAGGCCTGGCCAAGGATGCCTGGGAGATCCATCGGGA
GTCGCTGCNGCTGGAN
>OriGene 3' read for NM_198291 unedited
GGCCATGGCATGGCACTTCCGGTCCAGGAAAGCACTGGGGCAGGGTCACAGGCATGCCAC
CCGGGTTCTGTTGCAAGAAACAGACTATCACCGCGGCCGCAATCTATAGTCGAGTTTTTT
TTTTTTTTTTTTTTTTTTCAGAGGTCTGTTTGTGTTTAATCACACAATATGCAAAGTATT
TACAACCAATTCTGGATACCCCCCCACCCCCCGCAAGTTTTTTTTTTGGAATTTCAGAGC
CCCAGGCCCGGCCCATAGCCAGGGGTCCCCCAGGCCTCTGCATAGTCATCTGAAATCTAC
AAAACACTGTTAAAAAAAAAAAAAGGACAGTTTTAACACACCTTACACAAAGGGCCTTAA
GCAGTTGGAGAGGGATTTGAGAGCTCGCTGGGGTGAGTGAGCCCATATTTGACTGGAATG
GACGGGATAACACTTGGGTAATAAAGCCCTTTGAAAGGAAAATTTGATCTTTCTTAGGCA
TCGCCTGCTTGGTCCCCTTCCCCTCTGCAACGTCCTGCCTAGGTCTTTTACCCTTTTCAG
TGGGTATGCTTTCTCCCTCCCACAGCGCTCTTTTTTCTTTCCCTTTTTGTCCGCATTCCC
TCAGTGTCTCCCCCCCTGTGTTTTTTTTTCTTCCGCCCCTAGGCGTTCGGGGTCCCGTTC
GTTTTGTTTTGCTTCGTTGCCGTGTTGTGCGCGCGACCGCCGCCGGCGTGTTTTTTGTTG
TGGTTTTCCACCGCGGCTGGTGCGGCGGTTGGATGTTTTAGACGCCGGGTGAGTGCGTGT
GATTCGGTAGCCTCCTATCGAGATGGAGTGTTGAGTCCCCCATTTTCCTTTTCGTTTATT
GCTCCCCTCTTTTCGCCCCTTTTTTTTGTTTCTCCGCCCTCCCTGTCCTGTCAGTCTGGT
TGTCTCGTTAATTCATTTATATTAAAAA
Restriction Sites Please inquire     
ACCN NM_198291
Insert Size 3711 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_198291.1, NP_938033.1
RefSeq Size 4044 bp
RefSeq ORF 1611 bp
Locus ID 6714
Cytogenetics 20q11.23
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Stem cell relevant signaling - JAK/STAT signaling pathway
Protein Pathways Adherens junction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Focal adhesion, Gap junction, GnRH signaling pathway, Tight junction, VEGF signaling pathway
Gene Summary 'This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.

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