PTP4A2 (NM_080391) Human Untagged Clone

CAT#: SC109921

PTP4A2 (untagged)-Human protein tyrosine phosphatase type IVA, member 2 (PTP4A2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTP4A2
• Synonyms: HH7-2; HH13; HU-PP-1; OV-1; PRL-2; PRL2; ptp-IV1a; ptp-IV1b; PTP4A; PTPCAAX2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109921 sequence for NM_080391 edited (data generated by NextGen Sequencing)
  ATGAACCGTCCAGCCCCTGTGGAGATCTCCTATGAGAACATGCGTTTTCTGATAACTCAC
  AACCCTACCAATGCTACTCTCAACAAGTTCACAGAGGAACTTAAGAAGTATGGAGTGACG
  ACTTTGGTTCGAGTTTGTGATGCTACATATGATAAAGCTCCAGTTGAAAAAGAAGGAATC
  CACGTTCTAGATTGGCCATTTGATGATGGAGCTCCACCCCCTAATCAGATAGTAGATGAT
  TGGTTAAACCTGTTAAAAACCAAATTTCGTGAAGAGCCAGGTTGCTGTGTTGCAGTGCAT
  TGTGTTGCAGGATTGGGAAGGGCACCTGTGCTGGTTGCACTTGCTTTGATTGAATGTGGA
  ATGAAGTACGAAGATGCAGTTCAGTTTATAAGACAAAAAAGAAGGGGAGCGTTCAATTCC
  AAACAGCTGCTTTATTTGGAGAAATACCGACCTAAGATGCGATTACGCTTCAGAGATACC
  AATGGGCATTGCTGTGTTCAGTAG
  
  Clone variation with respect to NM_080391.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_080391 unedited
  GCACATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGCCGCCGCCGCCG
  CCGCCGCCGAGGTGACTGAGGAGAGAGGCGCCTCCTCGCTCCCGCCACCGCCGGACTTCA
  ATGCCCAGTCCCCAGCTCGCCAGCGTTTTTCGTTGGAATATACGTTGCACATTTATGGCG
  ATTCTGAGTGTGAGGGCAGACTTCTGCCAGGCTCAGCACAGCATTTTCGCTGACAAGTGA
  GCTTGGAGGTTCTATGTGCCATAATTAACATTGCCTTGAAGACTCCTGGACACCGAGACT
  GGCCTCAGAAATAGTTGGCTTTTTTTTTTTTTTAATTGCAAGCATATTTCTTTTAATGAC
  TCCAGTAAAATTAAGCATCAAGTAAACAAGTGGAAAGTGACCTACACTTTTAACTTGTCT
  CACTAGTGCCTAAATGTAGTAAAGGCTGCTTAAGTTTTGTATGTAGTTGGATTTTTTGGA
  GTCCGAAGGTATCCATCTGCAGAAATTGAGGCCCAAATTGAATTTGGATTCAAGTGGATT
  CTAAATACTTTGCTTATCTTGAAGAGAGAAGTTTCATAAGGAATAAACAAGTTGAATAGA
  GAAAACACTGATTGATAATAGGCATTTTAGTGGTCTTTTTAATGTTTTCTGCTGTGAAAC
  ATTTCAAGATTTATTGATTTTTTTTTTTCACTTTCCCCATNACACTCACACGCACGCTCA
  CACTTTTTATTTGCCATAATGAACCGTCCAGCCCCTGTGGAGATCTCCTATGAGAACATG
  CGTTTTCTGATAACTCACAACCCTACAATGCTACTCTCAACAAGTCACAGAAGAACTTAG
  AAGTTNGAGTGACGATTTTTGTTCGAGTTTGTGATGCTACATATGATAAAGCTCCANTGA
  AAAAAAGGNATCCACGTTCTAAATGGCCATTTGATGAGGAGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_080391 unedited
  ATGGACCGCGGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTACTAAAATGCCCA
  GTGGGCTTAAGGCTGCCAGACTGCACGCACATCTACAGCAACAAGGGCTTCTATTCCATC
  TACAACTTGGATCGGGGGAAAAGGGAGATGTAGGAGAGGAAGGAAAAAAGAGGGGAAAAA
  TATACCACCAACCCTCCCCCACAAAAAAAGGGAAAAAAAAAATCCCACCACAGGGAGATC
  TATGTGCCAAGCATAATGGAAGAGTGTGCTCCCCAAACAGATGGTTTTGCACAGGCTAAT
  GTTCTGCTGGTTTTCCTTAAAGACCTATTTTGAAAAAGTTTAAAAAGACAGGAGATTTCA
  AAATAATTCAATCCTGGCAGAAATTCAAACTCCAAAACTAGGAGCAAAATCATCCTTCAC
  TGAATTAATTCCTTTTCTCTTTCTCTTTTCTTAAACATTTTATTCATTTTATAGAGAGAT
  TTCTTTTTTGTTTGCTTTTGTTCCAATCATTAGGAGAGTGGTTGAGGAGTACTGAATCCA
  TCACTACTTTGATGACACAGGTAATATTCCAGATTCACATTTCCAGGTACCAAGAGTTCC
  CTCTAAATGGCACAATCAAGTCAGCCTTCGTTTACATTTCCTTCTACTGAACACAGCAAT
  GCCCATTGGTATCTCTGAAGCGTAATCGCATCTTAAGTCGGTATTTCTCCAAATAAAGCA
  GCTGTTTGGAATTGAACGCTCCCCTTCTTTTTTGTCTTATAACTGAACTGCATCTTCGTA
  CTTCATCCACATTCAATCAAAGCAGTGAACCAGCACAGGTGCCCTTTCCAATCCTGCACA
  CAATGCACTGCAACACAGCAACCTGGCTCTCACGAAATTTGGTTTTTACAGGNTAAACCA
  TCTCTACATCTGATAGGGGGTGGAGCTCATCATAAAGGCCATCTAAACGCGGATCCTCTC
  TTTCACTGGAGCTTATATTGTACCTACCACTCCACN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_080391
• ORF Size: 504 bp
• Insert Size: 2150
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_080391.1, NP_536316.1
• RefSeq Size: 2084
• RefSeq ORF: 504
• Locus ID: 8073
• Domains: Y_phosphatase, PTPc_motif
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1, 6 and 7 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.