DYRK2 (NM_006482) Human Untagged Clone

CAT#: SC109929

DYRK2 (untagged)-Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DYRK2
• Synonyms: FLJ21217; FLJ21365
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_006482 edited
  ATGTTAACCAGGAAACCTTCGGCCGCCGCTCCCGCCGCCTACCCGACCGGCCGAGGTGGG
  GACAGCGCCGTTCGTCAGCTTCAGGCTTCCCCGGGGCTCGGTGCAGGGGCCACCCGGAGC
  GGAGTGGGGACTGGCCCGCCCTCCCCCATCGCCCTGCCGCCTCTCCGGGCCAGCAACGCT
  GCCGCCGCAGCCCACACGATTGGCGGCAGTAAGCACACAATGAATGATCACCTGCATGTC
  GGCAGCCACGCTCACGGACAGATCCAGGTTCAACAGTTGTTTGAGGATAACAGTAACAAG
  CGGACAGTGCTCACGACACAACCAAATGGGCTTACAACAGTGGGCAAAACGGGCTTGCCA
  GTGGTGCCAGAGCGGCAGCTGGACAGCATTCATAGACGGCAGGGGAGCTCCACCTCTCTA
  AAGTCCATGGAAGGCATGGGGAAGGTGAAAGCCACCCCCATGACACCTGAACAAGCAATG
  AAGCAATACATGCAAAAACTCACAGCCTTCGAACACCATGAGATTTTCAGCTACCCTGAA
  ATATATTTCTTGGGTCTAAATGCTAAGAAGCGCCAGGGCATGACAGGTGGGCCCAACAAT
  GGTGGCTATGATGATGACCAGGGATCATATGTGCAGGTGCCCCACGATCACGTGGCTTAC
  AGGTATGAGGTCCTCAAGGTCATTGGGAAGGGGAGCTTTGGGCAGGTGGTCAAGGCCTAC
  GATCACAAAGTCCACCAGCACGTGGCCCTAAAGATGGTGCGGAATGAGAAGCGCTTCCAC
  CGGCAAGCAGCGGAGGAGATCCGAATCCTGGAACACCTGCGGAAGCAGGACAAGGATAAC
  ACAATGAATGTCATCCATATGCTGGAGAATTTCACCTTCCGCAACCACATCTGCATGACG
  TTTGAGCTGCTGAGCATGAACCTCTATGAGCTCATCAAGAAGAATAAATTCCAGGGCTTC
  AGTCTGCCTTTGGTTCGCAAGTTTGCCCACTCGATTCTGCAGTGCTTGGATGCTTTGCAC
  AAAAACAGAATAATTCACTGTGACCTTAAGCCCGAGAACATTTTGTTAAAGCAGCAGGGT
  AGAAGCGGTATTAAAGTAATTGATTTTGGCTCCAGTTGTTACGAGCATCAGCGTGTCTAC
  ACGTACATCCAGTCGCGTTTTTACCGGGCTCCAGAAGTGATCCTTGGGGCCAGGTATGGC
  ATGCCCATTGATATGTGGAGCCTGGGCTGCATTTTAGCAGAGCTCCTGACGGGTTACCCC
  CTCTTGCCTGGGGAAGATGAAGGGGACCAGCTGGCCTGTATGATTGAACTGTTGGGCATG
  CCCTCACAGAAACTGCTGGATGCATCCAAACGAGCCAAAAATTTTGTGAGCTCCAAGGGT
  TATCCCCGTTACTGCACTGTCACGACTCTCTCAGATGGCTCTGTGGTCCTAAACGGAGGC
  CGTTCCCGGAGGGGGAAACTGAGGGGCCCACCGGAGAGCAGAGAGTGGGGGAACGCGCTG
  AAGGGGTGTGATGATCCCCTTTTCCTTGACTTCTTAAAACAGTGTTTAGAGTGGGATCCT
  GCAGTGCGCATGACCCCAGGCCAGGCTTTGCGGCACCCCTGGCTGAGGAGGCGGTTGCCA
  AAGCCTCCCACCGGGGAGAAAACGTCAGTGAAAAGGATAACTGAGAGCACCGGTGCTATC
  ACATCTATATCCAAGTTACCTCCACCTTCTAGCTCAGCTTCCAAACTGAGGACTAATTTG
  GCGCAGATGACAGATGCCAATGGGAATATTCAGCAGAGGACAGTGTTGCCAAAACTTGTT
  AGCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006482 unedited
  CTTTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGAGAGCGGGGGG
  CTCGCGGCGGCGGGCCCCGGCCGAGGGGATGCAGTGGACTGTGTGTGTCTGGCTGTAGCA
  GACGCGAGGCGGCGACGAGGCGCCGGGGACCCGCGCGAGGGGCGGCCGGGAGGCGGCGGC
  GGCGGCCGCCAGAAGTAGCAGCAGGACCGGCGGCGGCGACGGCAGCCCTGAAATGCATTT
  TCCTCTCCAGCGGCCATGTTAACCAGGAAACCTTCGGCCGCCGCTCCCGCCGCCTACCCG
  ACCGGCCGAGGTGGGGACAGCGCCGTTCGTCAGCTTCAGGCTTCCCCGGGGCTCGGTGCA
  GGGGCCACCCGGAGCGGAGTGGGGACTGGCCCGCCCTCCCCCATCGCCCTGCCGCCTCTC
  CGGGCCAGCAACGCTGCCGCCGCAGCCCACACGATTGGCGGCAGTAAGCACACAATGAAT
  GATCACCTGCATGTCGGCAGCCACGCTCACGGACAGATCCAGGTTCAACAGTTGTTTGAG
  GATAACAGTAACAAGCGGACAGTGCTCACGACACAACCAAATGGGCTTACAACAGTGGGC
  AAAACGGGCTTGCCAGTGGTGCCAGAGCGGCAGCTGGACAGCATTCATAGACGGCAGGGG
  AGCTCCACCTCTCTAAAGTCCATGGAAGGCATGGNNGAAGGTGAAAGCCACCCCCATGAC
  ACCTGAACAAGCAATGAAGCAATACATGCANAAACTCACAGCCTTCGAACACCATGAGAT
  TTTCAGCTACCCTGAAATATATTTTCTTGGNGTCTAATGCNTAGAAGCGCCAGGGCATGA
  CAGGTGGGCCCCAACATGGTGGCTATGATGATGACCAGNGATCATATGTGCANGTGCCCC
  ACGATCACGTGGCTTACAGNNNATGANGTCCCTCAGGTCATTGGGAANGGGGAGCTTTGG
  NNCAGTGGTCAGGGCCTCGATCACAAGTCACCAGCCGTGGCCTTAGAGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006482 unedited
  CCGCTTTTAGAGTCGAGAAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTAAAAAACTTAAAGCATTGCCCTCATGTTTTTTATAAAAACAAAATGAACAACTTTCT
  TACCTTAAAATTAAGGGCTGAAAAGATACAAATGAGTAGAGTTATTGAGCAAATAAAAAC
  AGGGCTGAGCTACTCCTTTTCAACCCAGTAAGGCTCAACAATGGCGTATCTTTCAGGTTA
  CCAGCATCAGGGGACGGGAGCTCAGCTAACAAGTTTTGGCAACACTGGCCTCTGGTGAAT
  ATTCCCATTGGCATCTGTCATCTGCGCCAAATTAATCCTCATTTTGGAAGCTGAGCTAAA
  AGGGGGAGGGAACTTGGATATAAATGGGATAGCACCGGGGCTCTCAGTTATCCTTTTCAC
  TGACGTTTTCTCCCCGGGGGGAGGCTTTGGCAACCGCCTCCTCAGCCAGGGGTGCCGAAA
  AGCCTGGCCTGGGGTCATGCCCACTGCAGGATCCCACTCTAAACACTGTTTTAAGAAGTC
  AAGGAAAAGGGGATCATCACACCCCTTAAGCGCGTTCCCCCACTCTTTGCTCTCCGGTGG
  GCCCCTTATTTTCCCCCTCCAGTAACGGCCTCCGTTTAAGACCACAGAGCCCTCTGAGAG
  AGTCGTGACAGTGCAGTAACGGAGATAACCCCTGGGACCTCACAAATATTTTTGGCTCCG
  TTAGGATGCCTCCACACAGTTCCTGGGGAGGGCATGCCCCAACATGTTTAATCATACAGG
  GCCAGTGTGGTTCCCCTTTCATCCTCCCCCAGGCAGAAGGGGNGTACCCCGTCAAGAAGC
  TCGGCTATAAAGCACCCCAAGCCTCCCAATATAAATGGGCCTGCCATTCCCTGGCCCCGA
  AGATCACTTTTGGGACCCCGTAAATACGCGAACGGAAGTACCTGTAAACACCCGGAGCTC
  GGACAACGGGAGCCAAATACATTCTCTTATACCGTTCTACCTGTTGTCTTAACATTGTCN
  CAGGCTTAAGCCCAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006482
• ORF Size: 1806 bp
• Insert Size: 2250
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006482.1, NP_006473.1
• RefSeq Size: 3615
• RefSeq ORF: 1806
• Locus ID: 8445
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) includes the 149 bp insert in the 5' end of the transcript and thus results in a longer amino-terminal protein.