RNF128 (NM_194463) Human Untagged Clone

CAT#: SC110628

RNF128 (untagged)-Human ring finger protein 128 (RNF128), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF128
• Synonyms: GRAIL
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110628 sequence for NM_194463 edited (data generated by NextGen Sequencing)
  ATGGGGCCGCCGCCTGGGGCCGGGGTCTCCTGCCGCGGTGGCTGCGGCTTTTCCAGATTG
  CTGGCATGGTGCTTCCTGCTGGCCCTGAGTCCGCAGGCACCCGGTTCCCGGGGGGCTGAA
  GCAGTGTGGACCGCGTACCTCAACGTGTCCTGGCGGGTTCCGCACACGGGAGTGAACCGT
  ACGGTGTGGGAGCTGAGCGAGGAGGGCGTGTACGGCCAGGACTCGCCGCTGGAGCCTGTG
  GCTGGGGTCCTGGTACCGCCCGACGGGCCCGGGGCGCTTAACGCCTGTAACCCGCACACG
  AATTTCACGGTGCCCACGGTTTGGGGAAGCACCGTGCAAGTCTCTTGGTTGGCCCTCATC
  CAACGCGGCGGGGGCTGCACCTTCGCAGACAAGATCCATCTGGCTTATGAGAGAGGGGCG
  TCTGGAGCCGTCATCTTTAACTTCCCCGGGACCCGCAATGAGGTCATCCCCATGTCTCAC
  CCGGGTGCAGTAGACATTGTTGCAATCATGATCGGCAATCTGAAAGGCACAAAAATTCTG
  CAATCTATTCAAAGAGGCATACAAGTGACAATGGTCATAGAAGTAGGGAAAAAACATGGC
  CCTTGGGTGAATCACTATTCAATTTTTTTCGTTTCTGTGTCCTTTTTTATTATTACGGCG
  GCAACTGTGGGCTATTTTATCTTTTATTCTGCTCGAAGGCTACGGAATGCAAGAGCTCAA
  AGCAGGAAGCAGAGGCAATTAAAGGCAGATGCTAAAAAAGCTATTGGAAGGCTTCAACTA
  CGCACACTGAAACAAGGAGACAAGGAAATTGGCCCTGATGGAGATAGTTGTGCTGTGTGC
  ATTGAATTGTATAAACCAAATGATTTGGTACGCATCTTAACGTGCAACCATATTTTCCAT
  AAGACATGTGTTGACCCATGGCTGTTAGAACACAGGACTTGCCCCATGTGCAAATGTGAC
  ATACTCAAAGCTTTGGGAATTGAGGTGGATGTTGAAGATGGATCAGTGTCTTTACAAGTC
  CCTGTATCCAATGAAATATCTAATAGTGCCTCCTCCCATGAAGAGGATAATCGCAGCGAG
  ACCGCATCATCTGGATATGCTTCAGTACAGGGAACAGATGAACCGCCTCTGGAGGAACAC
  GTGCAGTCAACAAATGAAAGTCTACAGCTGGTAAACCATGAAGCAAATTCTGTGGCAGTG
  GATGTTATTCCTCATGTTGACAACCCAACCTTTGAAGAAGACGAAACTCCTAATCAAGAG
  ACTGCTGTTCGAGAAATTAAATCTTAA
  
  Clone variation with respect to NM_194463.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_194463 unedited
  NAAGTTAGAATTTGTATACGACTCACTATAGGCGGCCGCGCAATTCGCACCAGGCAGCCG
  CGGTAGCGGAGAAGACTGGAGCTCCGAGGAGCTGCATCTGCGGCAACCTGTGTGCTGACG
  CTACGTGCCTCCTGGCTCCGACGTAGCTCGCAGCTCCCCAGTCTCACTCCATTCCTTCCC
  CACCTGGCGCGCACCTGCTCAAGAACAGGGTCCTGCCAAGCGCTAGGAGGGCGCGTGCCA
  GGGGCGCTAGGGAACTGCGGAGCGCGCGCGCCATGGGGCCGCCGCCTGGGGCCGGGGTCT
  CCTGCCGCGGTGGCTGCGGCTTTTCCAGATTGCTGGCATGGTGCTTCCTGCTGGCCCTGA
  GTCCGCAGGCACCCGGTTCCCGGGGGGCTGAAGCAGTGTGGACCGCGTACCTCAACGTGT
  CCTGGCGGGTTCCGCACACGGGAGTGAACCGTACGGTGTGGGAGCTGAGCGAGGAGGGCG
  TGTACGGCCAGGACTCGCCGCTGGAGCCTGTGGCTGGGGTCCTGGTACCGCCCGACGGGC
  CCGGGGCGCTTAACGCCTGTAACCCGCACACGAATTTCACGGTGCCCACGGTTTGGGGAA
  GCACCGTGCAAGTCTCTTGGTTGGCCCTCATCCAACGCGGCGGNGGCTGCACCTTCGCAG
  ACAAGATCCATCTGGCTTATGAGAGAGGGGCGTCTGGAGCCGTCATCTNTAACTTCCCCG
  GGACCCCGCAATGAGTCATCCNCATGTCTCACCCGGGTGCAGTAGACATTGGTTGCATCA
  TGATCGGGCATCTGAAGGCACANNAATCTGCATCTATTCAAGAGCATACAGTGACATGGT
  CATANAAGTAGGAAAACATGGCCCTGGTGATCACTATCATNNTTCGNTCTGNGCCTTTTT
  ATATTACGCGCACTGTGGCTTTTTACTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_194463 unedited
  AAGNANNATCAATACAAATTGGGNCATATTTACAGCATTTCAAATCAGTGTACAAGAATG
  CAATGGTTTCATCCATTCAGCAAACAAAATACATGTCTGTTTTATTTTTGCCTAAATTCT
  GCTATAATTTGAACAAAATTCTAAAACAAAAGCCACACAGAGTACAAATAAAGTGCATTT
  TTAAATAGCTCTATTTAACTTTGGTGGATGAAGCTTCAAACTTTATATTAAGGCACCTGG
  AATTCTCCCCCCCTTCTTTTTCAAACACCAGGAAAATGCATTCACAAAATTTATAGTTAC
  ACGGACAGAATTTTAGTTTATCTAATGTAATTTTAGCCCATTTAGGTCAAACATAAACTC
  AATTTTCAAAGTAACATTGTTTGGAAAACATTTTCAACAGACTAATTTTACAGAACATTT
  TTTTTCTGTAGACTAATTCATGAACGAAGATCAATGACCAATATTAGTGTTACTTACTCT
  GTCATTAGCAATTTCAAACAGTATGATGATTCATATACTGAGCTTTTGAAAAATCCCACA
  AGTTTGAGAAATAGTTACACAGTATTTTTGTAAGGAATTTTTTGTCTAATCTTGTGTCAA
  GTTGATGTCACTAATATACCAATCAATTAAGTCCATAATCTCTGATAAACTATGGTTGAC
  AAATCACATGAAGTACATTCAGCCTAATTTTAAAAANAANNAAAGGTAAAATGAATATTT
  TGCTTTAAATCTTTCTATTAACTTAAACAGCTTAATAGACATTTCAAGAAGTACTCGCCT
  AAGTTTGCATTGCTTTTTACATTACCATTCCAGATCAATATAAGCACCTGGAGAAAAACC
  CTGCACATGTAGCCCAAGCTAAAGAAGTAGTTTTTTCATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_194463
• ORF Size: 1287 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_194463.1, NP_919445.1
• RefSeq Size: 2851
• RefSeq ORF: 1287
• Locus ID: 79589
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).