SLAP2 (SLA2) (NM_175077) Human Untagged Clone

CAT#: SC110686

SLA2 (untagged)-Human Src-like-adaptor 2 (SLA2), transcript variant 2


  "NM_175077" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SLA2
Synonyms C20orf156; MARS; SLAP-2; SLAP2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110686 sequence for NM_175077 edited (data generated by NextGen Sequencing)
ATGGGAAGTCTGCCCAGCAGAAGAAAATCTCTGCCAAGCCCAAGCTTGAGTTCCTCTGTC
CAAGGCCAGGGACCTGTGACCATGGAAGCAGAGAGAAGCAAGGCCACAGCCGTGGCCCTG
GGCAGTTTCCCGGCAGGTGGCCCGGCCGAGCTGTCGCTGAGACTCGGGGAGCCATTGACC
ATCGTCTCTGAGGATGGAGACTGGTGGACGGTGCTGTCTGAAGTCTCAGGCAGAGAGTAT
AACATCCCCAGCGTCCACGTGGCCAAAGTCTCCCATGGGTGGCTGTATGAGGGCCTGAGC
AGGGAGAAAGCAGAGGAACTGCTGTTGTTACCTGGGAACCCTGGAGGGGCCTTCCTCATC
CGGGAGAGCCAGACCAGGAGAGGCTCTTACTCTCTGTCAGTCCGCCTCAGCCGCCCTGCA
TCCTGGGACCGGATCAGACACTACAGGATCCACTGCCTTGACAATGGCTGGCTGTACATC
TCACCGCGCCTCACCTTCCCCTCACTCCAGGCCCTGGTGGACCATTACTCTGAGGGCTGG
CCCGCTCCCTGGCAAGGATATACCCCTACCTGTGACTGTGCAGAGGACACCACTCAACTG
GAAAGAGCTGGACAGCTCCCTCCTGTTTTCTGA

Clone variation with respect to NM_175077.1
>OriGene 5' read for NM_175077 unedited
AAAAGGGGAACCAANCCNAAACCCNNNGGGGTTCAAATTTGTATCCGACTCATATAGGCG
GCCCGCGAATCGGCACCAGCTCCAAGGACCCCACGCCTGTGTCTCTGTGACAGAGCTCAA
GGGCCCTGGGCCTTCCCTCCCTGGCTCGGCTGTGCTTGGGAGGGTTCCCCAGTCCAGAAT
CCCTAAGGAGCATGGGGCAGCTGATCCATCCCTGGTGTACAAACTGCTGACTGCAGACAG
ATGCTGAGCTACCCAAACCAACACCTAGCCTCTCCCTGAAGATCCTCCCAGGCTGAGAGA
GTTCTGGGTGTCCTAGGACCAAGGACACTGGCAGACTTCCAGAAGGGCCCCCAAAGCCCT
AACCTGTCCAGCCAGAGCATGCGTCTCAGCAGAGCTGTCTTCCCAAGCCTTTGATGACAA
ACCAATTTCCCTCGATGATGTGCTTCTGAGTGCTCTGCTGAGGAACAATGGGAAGTCTGC
CCAGCAGAAGAAAATCTCTGCCAAGCCCAAGCTTGAGTTCCTCTGTCCAAGGCCAGGGAC
CTGTGACCATGGAAGCAGAGAGAAGCAAGGCCACAGCCGTGGCCCTGGGCAGTTTCCCGG
CAGGTGGCCCCGGCCGAGCTGTCGCTGAGACTCGNGGAGCCATTGACCATCGTCTCTGAG
GATGGAGACTGGTGGACGGTGCTGTCTGAAGTCTCAGGCAGAGAGTATAACATCCCCAGC
GTCCACGTGGCCAAAGTCTCCCATGGGTGGCTGTATGAGGGCCTGAGCANGGAGAAAGCA
NAGAACTGCTGTTGTTACCTGGGAACCCTGGAGGGGCCTTCCTCATCGGGAGAGCCAGCA
CAAGGAGAGCTCTTACTCTTTGTCAGTCCGCCTCACCCCCCTGCATTCTGGGACCGGATC
AGCACTTCGGGATCCCTGCCTGACCAGGGCTGCTG
Restriction Sites NotI-NotI     
ACCN NM_175077
ORF Size 633 bp
Insert Size 2500
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_175077.1, NP_778252.1
RefSeq Size 2447
RefSeq ORF 633
Locus ID 84174
Protein Families Druggable Genome, Transcription Factors
Gene Summary This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2, also known as SLAP-2-v) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (b) is shorter and has a distinct C-terminus, compared to isoform a.

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