MRPL43 (NM_176793) Human Untagged Clone

CAT#: SC110693

MRPL43 (untagged)-Human mitochondrial ribosomal protein L43 (MRPL43), nuclear gene encoding mitochondrial protein, transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MRPL43
• Synonyms: bMRP36a; L43mt; MRP-L43
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_176793, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACGGCGCGCGGGACTCCGAGCCGCTTCTTGGCCAGCGTTCTCCACAACGGACTGGGTCGCTATGTGC
  AGCAGCTGCAGCGTCTGAGCTTCAGCGTCAGCCGCGACGGCGCCTCGTCTCGCGGCGCCAGGGAGTTCGT
  GGAGCGGGAGGTGATCGACTTCGCCCGACGGAATCCAGGGGTCGTAATATATGTAAACTCGCGTCCGTGC
  TGCGTGCCCAGAGTAGTGGCCGAATACCTTAACGGGGCTGTGCGCGAGGAGAGCATCCACTGCAAGTCGG
  TCGAGGAGATCTCGACGCTGGTGCAGAAGCTGGCCGACCAGTCGGGCTTGGACGTGATCCGCATCCGCAA
  GCCCTTCCACACCGACAACCCTAGCATCCAGGGCCAGTGGCACCCCTTCACCAACAAGCCGACCACGTTC
  CGCGGGCTACGCCCCCGAGAGGTTCAGGATCCTGCCCCAGCCCAGGACACTGGCCTGAGACTGTCTGCAG
  TTGCACCGCAGATCCTCCTGCCCGGCTGGCCCGACCCAATATCAGTTCAGTCATCCGATCTTCCTTGGGG
  AAATACCCATTACCGTCCTGAACCCTTGTCATCCACTACTTGGCTATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_176793 unedited
  GGGGGGGGGGGGGNNNNNNNNNCTCCCCCCCCNCGGTTCAGATTTGNATACGACTCACTA
  TAGGCGGCCGCGNATATCGCACCAGGCTCCGCGGCCTCCAAGCTGTAGCTATGACGGCGC
  GCGGGACTCCGAGCCGCTTCTTGGCCAGCGTTCTCCACAACGGACTGGGTCGCTATGTGC
  AGCAGCTGCAGCGTCTGAGCTTCAGCGTCAGCCGCGACGGCGCCTCGTCTCGCGGCGCCA
  GGGAGTTCGTGGAGCGGGAGGTGATCGACTTCGCCCGACGGAATCCAGGGGTCGTAATAT
  ATGTAAACTCGCGTCCGTGCTGCGTGCCCAGAGTAGTGGCCGAATACCGTGAGTGGGGCC
  GGGCTCGGGCTGGAGGGCGGGATCAGGGGCTCGACCCGCTATCCTCCTTCTCGCTTGGTC
  GCACCGGCCAGCTTCCACCCACTCTCACCCCTCTTCTGCCAGTTAACGGGGCTGTGCGCG
  AGGAGAGCATCCACTGCAAGTCGGTCGAGGAGATCTCGACGCTGGTGCAGAAGCTGGCCG
  ACCAGTCGGGCTTGGACGTGATCCGCATCCGCAAGCCCTTCCACACCGACAACCCTAGCA
  TCCAGGGCCAGTGGCACCCCTTCACCAACAAGCCGACCACGTTCCGCGGGCTACGCCCCC
  GAGAGGTTCAGGATCCTGCCCCAGCCCAGGTGCAAGCACAGTGAAGAGTTGCCCCACCAA
  CTGCAGCCCCAGGCTTTGGACTGTTACTCCGGTAAAGGTGGTTCTTCCCCTTTGGGATTC
  CAAGCCCAGGGCAATGGAACCCATCATGGGGCAANGTGACAGAGTTCTGCTTGGGATAAT
  GAAGAGCTGCCTGGTTCTTTCCAGTGCCTGCTTCTGGGGGCAGTGACCCTGTGAACCACT
  CATTTTATGCAAGTGGCATCCCTAAAACTGAGATN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_176793
• ORF Size: 609 bp
• Insert Size: 3500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_176793.1, NP_789763.1
• RefSeq Size: 767
• RefSeq ORF: 609
• Locus ID: 84545
• Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 3' UTR and has multiple coding region differences, compared to variant 1. This results in a longer isoform (c) with a distinct C-terminus compared to isoform a.