HPS4 (NM_022081) Human Untagged Clone

CAT#: SC110711

HPS4 (untagged)-Human Hermansky-Pudlak syndrome 4 (HPS4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HPS4
• Synonyms: BLOC3S2; LE
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110711 sequence for NM_022081 edited (data generated by NextGen Sequencing)
  ATGGCCACCTCTACCTCCACAGAGGCAAAGTCAGCCTCGTGGTGGAATTATTTTTTTCTT
  TATGATGGTTCCAAGGTAAAGGAAGAAGGCGATCCAACAAGAGCTGGCATTTGTTACTTT
  TATCCTTCCCAGACCCTGCTAGACCAACAGGAGTTGCTTTGTGGACAGATTGCTGGAGTT
  GTCCGCTGTGTTTCTGACATTTCTGACTCTCCTCCTACTCTTGTTCGTCTGAGAAAACTG
  AAGTTTGCCATAAAAGTTGATGGAGATTACCTTTGGGTGCTGGGCTGTGCTGTGGAGCTC
  CCTGATGTCAGCTGCAAGCGGTTTCTGGATCAGCTAGTTGGATTCTTTAATTTTTACAAT
  GGACCTGTTTCCCTAGCTTATGAGAACTGTTCTCAGGAAGAACTGAGCACGGAGTGGGAC
  ACCTTCATCGAGCAAATTCTGAAAAACACCAGTGATCTGCATAAGATTTTCAATTCCCTC
  TGGAACTTGGACCAAACTAAAGTGGAGCCCCTGTTGTTGCTGAAGGCAGCCCGCATTCTG
  CAGACCTGCCAGCGCTCGCCTCACATTCTCGCTGGCTGCATCCTCTATAAAGGACTGATT
  GTCAGCACCCAACTCCCGCCCTCCCTCACCGCCAAGGTCCTGCTTCACCGAACAGCACCT
  CAGGAGCAGAGACTCCCTACGGGAGAGGATGCCCCGCAGGAACATGGAGCGGCATTGCCC
  CCGAATGTCCAGATTATCCCTGTTTTTGTGACCAAAGAGGAAGCCATTAGTCTCCACGAG
  TTCCCGGTGGAACAGATGACAAGGTCTCTAGCATCTCCAGCAGGACTCCAGGATGGTTCA
  GCCCAGCACCATCCAAAGGGTGGGAGCACATCTGCCCTGAAAGAAAACGCCACTGGCCAT
  GTGGAATCCATGGCCTGGACCACCCCAGATCCCACATCCCCTGACGAAGCTTGTCCAGAT
  GGCAGGAAGGAGAACGGATGCTTGTCTGGCCATGATCTGGAGAGCATCAGGCCCGCAGGA
  CTGCACAACTCTGCCAGGGGTGAGGTTCTTGGCCTCAGCTCCTCCCTGGGGAAGGAACTA
  GTCTTTCTCCAAGAAGAACTCGACTTGTCTGAAATCCACATTCCAGAGGCTCAGGAAGTG
  GAAATGGCCTCAGGTCATTTTGCCTTCCTACATGTGCCTGTTCCAGATGGCAGGGCTCCT
  TACTGCAAGGCATCTCTCAGCGCCTCCAGCAGCCTGGAACCCACGCCTCCTGAGGACACA
  GCCATCAGCAGCTTGCGCCCTCCCTCTGCTCCTGAGATGCTGACCCAGCATGGAGCCCAA
  GAGCAGCTCGAAGACCATCCTGGCCATAGCAGCCAAGCCCCCATTCCCAGAGCAGACCCT
  CTCCCCAGAAGGACCCGCAGGCCCTTGTTATTGCCTCGCTTAGATCCAGGACAGAGAGGA
  AACAAGCTTCCCACGGGGGAACAAGGCCTGGATGAGGATGTTGATGGGGTCTGTGAAAGC
  CACGCAGCCCCTGGTCTGGAATGCAGTTCAGGCTCAGCAAACTGTCAGGGTGCTGGCCCC
  TCTGCAGATGGAATCAGCTCCAGGCTGACACCAGCAGAGTCCTGCATGGGGCTCGTGAGG
  ATGAATCTCTACACTCACTGCGTCAAAGGGCTGGTGCTGTCCCTGCTGGCTGAGGAGCCG
  CTGCTGGGAGACAGCGCAGCCATAGAGGAAGTGTACCACAGCAGCCTGGCTTCACTGAAT
  GGGCTGGAAGTCCACCTGAAAGAGACGCTGCCCAGGGATGAGGCAGCCTCCACGAGCAGC
  ACCTACAACTTCACACATTACGACCGCATTCAGAGCTTGCTGATGGCAAACCTGCCACAG
  GTGGCCACCCCGCAGGATCGCCGCTTCCTCCAGGCCGTCAGCCTGATGCATAGCGAATTT
  GCCCAGCTGCCCGCGCTTTATGAAATGACTGTCAGAAATGCCTCCACGGCTGTGTACGCC
  TGTTGCAACCCCATCCAGGAGACATATTTCCAGCAGCTGGCACCTGCAGCACGGAGCTCC
  GGCTTCCCAAACCCTCAGGATGGCGCCTTCAGCCTCTCCGGCAAAGCAAAGCAGAAGCTG
  CTGAAGCACGGGGTGAACTTGCTCTGA
  
  Clone variation with respect to NM_022081.4
  1857 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022081 unedited
  GAATTCGGCACGAGGCGGGGCGGCGCGTGACCTAAGGCCTCTCTGCCGCGCGCGCAGAGC
  CAAGGCACTGATGTTTGAACTGGAAACTTCAAAACGTTTAATAAGAGTCTTCAGGATGGG
  TTTGAACTAGACAAGCTAGAAATTTCTTTAGAACACCAGCTCTAGCATGCATCTCCCACT
  TTTGGCTTTCCTGGAGAGGAGCTTGAAGAGGTGGTTCTGCAGACAGCCACAGTGATACTT
  AGGAAACCAGAGGAATGGATTTGACTTTTCTGCTAGGATTCTCTGTTATAGTTTCTCCCT
  GAGTTGTAAGAGGCATGGAAATATACATGAAACTGAAGAACCTGCAAGGAAGGGAAGTGG
  AACTTTCCATGCTGAGTGAAAACTAACCAAGTGGCAGTTGTGACTGAAAACACTGAAACC
  TACCACGTCCAGATTCACTGGATTGGGGGATAGAGGAACGGTCACAGCTAGGGAGAAAGA
  AGTGATACCGGAAAAGAAAACCTAAATGAAGAGAATGAGGATGACTGCACAGTAGATGGC
  CACCTCTACCTCCACAGAGGCAAAGTCAGCCTCGTGGTGGAATTATTTTTTTCTTTATGA
  TGGTTCCAAGGTAAAGGAAGAAGGCGATCCAACAAGAGCTGGCATTTGTTACTTTTATCC
  TTCCCAGACCCTGCTAGACCAACAGGAGTTGCTTTGTGGACAGATTGCTGGGAGTGTCCG
  CTGTGTTTCTGACATTTCTGACTCTCCTCCTACTCTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022081 unedited
  GTTTTTATCTATGCCNCGCGGCCCGCATCCTAGGATCGAGTTTTTTTTTTTTTTTTTTCA
  TTTTTTGGCTATTTTATTTCTAGCCCTTGGAAGCTTGTTTCAAAAAAAAGAACCATATCA
  TAAACATCAGATATCAGTTCACTGACATGAAATTATTAACAATACAACTCTCAAATGGAA
  TCTCAAGTACTTCCAGTAAACATTCAGTTAAGATTTTGACAAATATTTTCATCCTGCAGT
  CTGTCTCATACTGTCAAAAAAATGTCTGACTATAACGTAATAGAACTGAGGTTCTAAGTA
  CCACACAAGCCCAGGAACACACAGCTGAGTGTCGCTCCCTTTCACGCAGCCACCATTGAA
  AAGCACAGTGCTTTTACCCCCAGACATCTTGTAAACTCCTATTTAGGGACACTCGCTCGA
  GAGGAACCAGCTGCACGGCCCACTTGTACTCAAAGGCAGCGCACCTTGGTCCTGTTGTCA
  CTGAATTCTCACGGCTCAGCCCCCAGAGCTCTTATAAAGGGACCCCTCAAAGCCAAACTC
  CCTTCCATATTATTACCGCTTGCCCCCATTGCGGGCCCCAATATACACCCCCTACCACCG
  ACCATAGCCTCACCAGCATCCAACCACCCGGTCCCACCGTGCCGCCGCTTCCCCTGCAGA
  CCCACCCGGCCCTCCCCTCTTGAGCGCCTTGCCAAACCCCCCCCGCCCTGCGCCACCGGT
  TTCCCTCTGCTCACACCTCCGGGCATTAGTCGTGCCCTCCCCCTCCTACCACTCTCTCTT
  CCGGGCTCCAACCCCATTCTTTGCATCATCCCCCCCCCTCCCCCCCCATAACCTTCTCCC
  CCCCCGTGGCGCTATCCACCCCTTCTCGCATTATAGTAATCAGCCCCCTCCGTTTCCCAA
  CCACACCGTACCCTTCCCCCTCCCTCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022081
• ORF Size: 2127 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_022081.4, NP_071364.4
• RefSeq Size: 4539
• RefSeq ORF: 2127
• Locus ID: 89781
• Gene Summary: This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
  Transcript Variant: This variant (1) encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.