RAIDD (CRADD) (NM_003805) Human Untagged Clone

CAT#: SC111084

CRADD (untagged)-Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CRADD
• Synonyms: MRT34; RAIDD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003805 edited
  GAATTCGGCACGAGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA
  GAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA
  GGGGCAGGTTCCCTAACAGTCAGGATTCCGGTTGCAGTTTTTCTCCCCCGCCCCAAAGAT
  ACGTGGTTGCAGACGGAGAAATGGAGGCCAGAGACAAACAAGTACTCCGCTCACTTCGCC
  TGGAGCTGGGTGCAGAGGTATTGGTGGAGGGACTGGTTCTTCAGTACCTCTACCAGGAAG
  GAATCTTGACGGAAAACCATATTCAAGAAATCAATGCTCAAACCACAGGCCTCCGGAAAA
  CAATGCTCCTGCTGGATATCCTACCTTCCAGGGGCCCTAAAGCATTTGATACATTCCTAG
  ATTCCCTACAGGAGTTTCCCTGGGTCAGGGAGAAGCTGAAGAAGGCAAGGGAAGAGGCCA
  TGACCGACCTGCCTGCAGGTGACAGATTGACTGGGATCCCCTCGCACATCCTCAACAGCT
  CCCCATCAGACCGGCAGATTAACCAGCTGGCCCAGAGGCTGGGCCCTGAGTGGGAGCCCA
  TGGTGCTGTCTCTGGGACTGTCCCAGACGGATATCTACCGCTGTAAGGCCAACCACCCCC
  ACAACGTGCAGTCGCAGGTGGTGGAGGCCTTCATCCGTTGGCGGCAGCGCTTCGGGAAGC
  AGGCCACCTTCCAGAGCCTGCACAACGGGCTGCGGGCTGTGGAGGTGGACCCCTCGCTGC
  TCCTGCACATGTTGGAGTGATGGTGCCTCCAGCAACCGCTGGGGAGTGTGTCCCTGAGTC
  ATGTGGGCTGAATCCTGACTTTCACTCAGAGCAGGTGGTTTTTTGTGTAGGTTTGTTTTT
  TATTTTTGATGATCTTCAGATGGAAGGAGAAAACAGGGTTTCCACTAGACATTACTTGAA
  AGGCCAGATTACTCAGCAGATCTCCCATGTTGGCTCAACAATTCTTTGTTTTTAATTGCT
  TGAAGATTGCATTGTTGTAATTGTTCAGTTTTTAAATGTGTAATGGCATTTTAATAGACT
  AGTAAATCACAGTGGTTCAAAATATATATCCATATATATATATATCCATATATATATCTC
  ATGTCATCACATTACAGGCAGGTGTCTCATATGTAAAACATTTACCTGAATGTTGTCTGA
  GGACTGAACTGTGGACTTTACTATTCATAATGATAAAATAATAAAATGCGAATTACTATA
  AAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003805 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGGGGCAGGTTCCCTAACAGTCAGGATTCCGG
  TTGCAGTTTTTCTCCCCCGCCCCAAAGATACGTGGTTGCAGACGGAGAAATGGAGGCCAG
  AGACAAACAAGTACTCCGCTCACTTCGCCTGGAGCTGGGTGCAGAGGTATTGGTGGAGGG
  ACTGGTTCTTCAGTACCTCTACCAGGAAGGAATCTTGACGGAAAACCATATTCAAGAAAT
  CAATGCTCAAACCACAGGCCTCCGGAAAACAATGCTCCTGCTGGATATCCTACCTTCCAG
  GGGCCCTAAAGCATTTGATACATTCCTAGATTCCCTACAGGAGTTTCCCTGGGTCAGGGA
  GAAGCTGAAGAAGGCAAGGGAAGAGGCCATGACCGACCTGCCTGCAGGTGACAGATTGAC
  TGGGATCCCCTCGCACATCCTCAACAGCTCCCCATCAGACCGGCAGATTAACCAGCTGGC
  CCAGAGGCTGGGCCCTGAGTGGGAGCCCATGGTGCTGTCTCTGGGACTGTCCCAGACGGA
  TATCTACCGCTGTAAGGCCAACCACCCCCACAACGTGCAGTCGCAGGTGGTGGAGGCCTT
  CATCCGTTGGCGGCAGCGCTTCGGGAAGCAGGCCACCTTCCAGAGCCTGCACAACGGGCT
  GCGGGCTGTGGAGGGTGGACCCCTCGCTGCTCCTGCACATGTTGGAGTGATGGTGCCTCC
  AGCACCGCTGGNGAGTGTGTCCCTGAGTCATGTGGGCTGAATCCTGACTTTACTCANAGC
  AGTGGTTTTTGNNGTAGTTGTTTTTATTTTGAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003805 unedited
  AGCTCTGNACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTATAGTAAT
  TCGCATTTTATTATTTTATCATTATGAATAGTAAAGTCCACAGTTCAGTCCTCAGACAAC
  ATTCAGGTAAATGTTTTACATATGAGACACCTGCCTGTAATGTGATGACATGAGATATAT
  ATATGGATATATATATATATGGATATATATTTTGAACCACTGTGATTTACTAGTCTATTA
  AAATGCCATTACACATTTAAAAACTGAACAATTACAACAATGCAATCTTCAAGCAATTAA
  AAACAAAGAATTGTTGAGCCAACATGGGAGATCTGCTGAGTAATCTGGCCTTTCAAGTAA
  TGTCTAGTGGAAACCCTGTTTTCTCCTTCCATCTGAAGATCATCAAAAATAAAAAACAAA
  CCTACACAAAAAACCACCTGCTCTGAGTGAAAGTCAGGATTCAGCCCACATGACTCAGGG
  ACACACTCCCCAGCGGTTGCTGGAGGCACCATCACTCCAACATGTGCAGGAGCAGCGAGG
  GGTCCACCTCCACAGCCCGCAGCCCGTTGTGCAGGCTCTGGAAGGTGGCCTGCTTCCCGA
  AGCGCTGCCGCCAACGGATGAAGGCCTCCACCACCTGCGACTGCACGTTGTGGGGGTGGT
  TGGCCTTACAGCGGTAGATATCCGTCTGGGACAGTCCCAGAGACAGCACCATGGGCTCCC
  ACTCANGGCCCAGCCTCTGGGCCAGCTGGTTAATCTGCCGGTCTGATGGGGAGNNCTGTG
  AGATGTGCGAGGGGATCCCANTCATCTGTCACCTGCAGGCANNGTCGTCATGGCCTCTTC
  CTTTGCCTTNCTCAGCTTCTCCCTGACCCAGGNAAACTNCTGTANGN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003805
• ORF Size: 600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003805.3, NP_003796.1
• RefSeq Size: 1201
• RefSeq ORF: 600
• Locus ID: 8738
• Domains: DEATH, CARD
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1 and 2 encode the same isoform (1).