USP10 (NM_005153) Human Untagged Clone

CAT#: SC111097

USP10 (untagged)-Human ubiquitin specific peptidase 10 (USP10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USP10
• Synonyms: UBPO
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111097 sequence for NM_005153 edited (data generated by NextGen Sequencing)
  ATGGCCCTCCACAGCCCGCAGTATATTTTTGGAGATTTTAGCCCTGATGAATTCAATCAA
  TTCTTTGTGACTCCTCGATCTTCAGTTGAGCTTCCTCCATACAGTGGAACAGTTCTGTGT
  GGCACACAGGCTGTGGATAAACTACCTGATGGACAAGAATATCAGAGAATTGAGTTTGGT
  GTCGATGAAGTCATTGAACCCAGTGACACTTTGCCGAGAACCCCCAGCTACAGTATTTCA
  AGCACACTGAACCCTCAGGCCCCTGAATTTATTCTCGGTTGTACAGCTTCCAAAATAACC
  CCTGATGGTATCACTAAAGAAGCAAGCTATGGCTCCATCGACTGCCAGTACCCAGGCTCT
  GCCCTCGCTTTGGATGGAAGTTCTAATGTGGAGGCGGAAGTTTTGGAAAATGATGGTGTC
  TCAGGTGGTCTTGGACAAAGGGAGCGTAAAAAGAAGAAAAAGCGGCCACCTGGATATTAC
  AGCTATTTGAAAGATGGTGGCGATGATAGTATCTCCACAGAAGCCCTGGTCAATGGCCAT
  GCCAATTCAGCAGTCCCGAACAGTGTCAGTGCAGAGGATGCAGAATTTATGGGTGACATG
  CCCCCGTCAGTTACGCCCAGGACTTGTAACAGCCCCCAGAACTCCACAGACTCTGTCAGT
  GACATTGTGCCTGATAGTCCTTTCCCCGGAGCACTCGGCAGTGACACCAGGACTGCAGGG
  CAGCCAGAGGGGGGCCCCGGGGCTGATTTTGGTCAGTCCTGCTTCCCTGCAGAGGCTGGC
  AGAGACACCCTGTCAAGGACAGCTGGGGCTCAGCCCTGCGTTGGTACCGATACTACTGAA
  AACCTTGGAGTTGCTAATGGACAAATACTTGAATCCTCGGGTGAGGGCACAGCTACCAAC
  GGGGTGGAGTTGCACACCACGGAAAGCATAGACTTGGACCCAACCAAACCCGAGAGTGCA
  TCACCTCCTGCTGACGGCACGGGCTCTGCATCAGGCACCCTTCCTGTCAGCCAGCCCAAG
  TCCTGGGCCAGCCTCTTTCATGATTCTAAGCCCTCTTCCTCCTCGCCGGTGGCCTATGTG
  GAAACTAAGTATTCCCCTCCCGCCATATCTCCCCTGGTTTCTGAAAAGCAGGTTGAAGTC
  AAAGAAGGGCTTGTTCCGGTGTCAGAGGATCCTGTAGCCATAAAGATTGCAGAGTTGCTG
  GAGAATGTAACCCTAATCCATAAACCAGTGTCGTTGCAACCCCGTGGGCTGATCAATAAA
  GGGAACTGGTGCTACATTAATGCTACACTGCAGGCATTGGTTGCTTGCCCGCCGATGTAC
  CACCTGATGAAGTTCATTCCTCTGTATTCCAAAGTGCAAAGGCCTTGTACGTCAACACCC
  ATGATAGACAGCTTTGTTCGGCTAATGAATGAGTTCACTAATATGCCAGTACCTCCAAAA
  CCCCGACAAGCTCTTGGAGATAAAATCGTGAGGGATATTCGCCCTGGAGCTGCCTTTGAG
  CCCACATATATTTACAGACTCCTGACAGTTAACAAGTCAAGCCTGTCTGAAAAGGGTCGA
  CAGGAAGATGCTGAGGAATACTTAGGCTTCATTCTAAATGGACTTCATGAGGAAATGTTG
  AACCTAAAGAAGCTTCTCTCACCAAGTAATGAAAAACTTACGATTTCCAACGGCCCCAAA
  AACCACTCGGTCAATGAAGAAGAGCAGGAAGAACAAGGTGAAGGAAGCGAGGATGAATGG
  GAACAAGTGGGCCCCCGGAACAAGACTTCCGTCACCCGCCAGGCGGATTTTGTTCAGACT
  CCAATCACCGGCATTTTTGGTGGACACATCAGGTCTGTGGTTTACCAGCAGAGTTCAAAA
  GAATCTGCCACTTTGCAGCCATTTTTCACGTTGCAGTTGGATATCCAGTCAGACAAGATA
  CGCACAGTCCAGGATGCACTGGAGAGCTTGGTGGCAAGAGAATCTGTCCAAGGTTATACC
  ACAAAAACCAAACAAGAGGTTGAGATAAGTCGAAGAGTGACTCTGGAAAAACTCCCTCCT
  GTCCTCGTGCTGCACCTGAAACGATTCGTTTATGAGAAGACTGGTGGGTGCCAGAAGCTT
  ATCAAAAATATTGAATATCCTGTGGACTTGGAAATTAGTAAAGAACTGCTTTCTCCAGGG
  GTTAAAAATAAGAATTTTAAATGCCACCGAACCTATCGGCTGTTTGCAGTGGTCTACCAT
  CACGGCAACAGTGCGACGGGCGGCCATTACACTACAGACGTCTTCCAGATCGGTCTGAAT
  GGCTGGCTGCGCATCGATGACCAGACAGTCAAGGTGATCAACCAGTACCAGGTGGTGAAA
  CCAACTGCTGAACGCACAGCCTACCTCCTGTATTACCGCCGAGTGGACCTGCTGTAA
  
  Clone variation with respect to NM_005153.2
  675 c=>t;1161 t=>g;1563 a=>g;2202 c=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005153 unedited
  NNNAAGGGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGAAG
  AGGCGGCGGCGGGGGAAGCAGCGTGAGCAGCCGGAGGATCGCGGAGTCCCAATGAAACGG
  GCAGCCATGGCCCTCCACAGCCCGCAGTATATTTTTGGAGATTTTAGCCCTGATGAATTC
  AATCAATTCTTTGTGACTCCTCGATCTTCAGTTGAGCTTCCTCCATACAGTGGAACAGTT
  CTGTGTGGCACACAGGCTGTGGATAAACTACCTGATGGACAAGAATATCAGAGAATTGAG
  TTTGGTGTCGATGAAGTCATTGAACCCAGTGACACTTTGCCGAGAACCCCCAGCTACAGT
  ATTTCAAGCACACTGAACCCTCAGGCCCCTGAATTTATTCTCGGTTGTACAGCTTCCAAA
  ATAACCCCTGATGGTATCACTAAAGAAGCAAGCTATGGCTCCATCGACTGCCAGTACCCA
  GGCTCTGCCCTCGCTTTGGATGGAAGTTCTAATGTGGAGGCGGAAGTTTTGGAAAATGAT
  GGTGTCTCAGGTGGTCTTGGACAAGGGAGCGTAAAAAGAGAAAAAGCGGCCACCTGGATA
  TTACAGCTATTTGAAAGATGGTGGCGATGATAGTATCTCCACAGAAGCCCTGGTCAATGG
  CCATGCCAATTCAGCAGTCCCGAACAGTGTCAGTGCAGAGGATGCAGAATTTATGGGTGA
  CATGCCCCCGTCAGTTACGCCCAGNACTTNGTACAGCCCCCAGAACTNCACAGACTCTGT
  CAGTGACATTGTGCCTGATAGTCCTTTCCCCGGACACTCGGCAGTGACACCAGGACTGCA
  GGNCAGCCAGAGGGGGGGCCCCGGNGCTGATNTTGGTCAGTCCTGCTTCCCTGCAGAGGC
  TGGCAGAGACACCCTGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005153 unedited
  NNGGGTACGACTATGNNACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTAAAACCAACTTTGGGATTTTTATTGAGGGGCGAC
  AACTTTATACTCCTAGATATCACTAAACTGGGTACAATTAGGGACCCCGCATTAGAGAAA
  AGCAGACCGCAGAATTAAACAGAGCAGACTGGAGGAGAGATCTTCATTATTTGCCCATTT
  TTCATTATGTGTACCCAGAAGCCTGAATGCCATTTGAAATCTTTTAATGGCAATAAAGTT
  ACAATCACCCATCTATGTAGACTAACATTTTAACTCCAAATATTTGATCTGCAATGGGTA
  CCTAAGCAGTTTCTCTCAGTACAATTATTAAAATTTTTCCTGGTAGGAACCAGCAACCTA
  TTTTTTAAGGTTATTTTTCTTTTGAAGGAAAAACTAATTCTTCTTTGATAACCGGCCCAT
  TTTTATCATTTATCAAAAACTAAAGGGTAGGGAAAAAAAGTGTGATGGATTAAAAAATTT
  CTTTTTTAAGGGAAGATAAAATTCATTTTCACAAATTTACCAATGTTGTTGCTGGTGCCA
  GATTTATTCCACTAAGCCATGAGACTGGGGATCAAATCCACTTTCTTATCTCAAGAATCA
  GCCTTATTTCAGAAAATGGGGTTTTGGGGATTTTCTAAATCAAGCAACAGTCTGTTTCAA
  CCCAATGATTTTTGATTGGAAGTTAAAAGTCACAAAAACTGGGTTTGTGCACCAACCCCC
  AGGGGATCTCTTTTTATTCTAGCCCATTTTTGACAAGGGGGAAAGAGTTCTCTCTCAAGA
  ACCCCTTAAGAAAAGCCGGAAATGAATGGGAAGGGGGGGTCCCACAAACCGGGACCGGGG
  AC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005153
• ORF Size: 2397 bp
• Insert Size: 3500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005153.1, NP_005144.1
• RefSeq Size: 3009
• RefSeq ORF: 2397
• Locus ID: 9100
• Domains: UCH
• Protein Families: Druggable Genome, Protease
• Gene Summary: Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013]
  Transcript Variant: This variant (2) lacks an alternate exon in the 5' end compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.