GCSF Receptor (CSF3R) (NM_000760) Human Untagged Clone

CAT#: SC111618

CSF3R (untagged)-Human colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CSF3R
• Synonyms: CD114; GCSFR; SCN7
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000760 edited
  GAATTCGGCACGAGGCAGGGGCTGGGCCAGAGGTGCCAACATGGGGAAACTGAGGCTCGG
  CTCGGAAAGGTGAAGTAACTTGTCCAAGATCACAAAGCTGGTGAACATCAAGTTGGTGCT
  ATGGCAAGGCTGGGAAACTGCAGCCTGACTTGGGCTGCCCTGATCATCCTGCTGCTCCCC
  GGAAGTCTGGAGGAGTGCGGGCACATCAGTGTCTCAGCCCCCATCGTCCACCTGGGGGAT
  CCCATCACAGCCTCCTGCATCATCAAGCAGAACTGCAGCCATCTGGACCCGGAGCCACAG
  ATTCTGTGGAGACTGGGAGCAGAGCTTCAGCCCGGGGGCAGGCAGCAGCGTCTGTCTGAT
  GGGACCCAGGAATCTATCATCACCCTGCCCCACCTCAACCACACTCAGGCCTTTCTCTCC
  TGCTGCCTGAACTGGGGCAACAGCCTGCAGATCCTGGACCAGGTTGAGCTGCGCGCAGGC
  TACCCTCCAGCCATACCCCACAACCTCTCCTGCCTCATGAACCTCACAACCAGCAGCCTC
  ATCTGCCAGTGGGAGCCAGGACCTGAGACCCACCTACCCACCAGCTTCACTCTGAAGAGT
  TTCAAGAGCCGGGGCAACTGTCAGACCCAAGGGGACTCCATCCTGGACTGCGTGCCCAAG
  GACGGGCAGAGCCACTGCTGCATCCCACGCAAACACCTGCTGTTGTACCAGAATATGGGC
  ATCTGGGTGCAGGCAGAGAATGCGCTGGGGACCAGCATGTCCCCACAACTGTGTCTTGAT
  CCCATGGATGTTGTGAAACTGGAGCCCCCCATGCTGCGGACCATGGACCCCAGCCCTGAA
  GCGGCCCCTCCCCAGGCAGGCTGCCTACAGCTGTGCTGGGAGCCATGGCAGCCAGGCCTG
  CACATAAATCAGAAGTGTGAGCTGCGCCACAAGCCGCAGCGTGGAGAAGCCAGCTGGGCA
  CTGGTGGGCCCCCTCCCCTTGGAGGCCCTTCAGTATGAGCTCTGCGGGCTCCTCCCAGCC
  ACGGCCTACACCCTGCAGATACGCTGCATCCGCTGGCCCCTGCCTGGCCACTGGAGCGAC
  TGGAGCCCCAGCCTGGAGCTGAGAACTACCGAACGGGCCCCCACTGTCAGACTGGACACA
  TGGTGGCGGCAGAGGCAGCTGGACCCCAGGACAGTGCAGCTGTTCTGGAAGCCAGTGCCC
  CTGGAGGAAGACAGCGGACGGATCCAAGGTTATGTGGTTTCTTGGAGACCCTCAGGCCAG
  GCTGGGGCCATCCTGCCCCTCTGCAACACCACAGAGCTCAGCTGCACCTTCCACCTGCCT
  TCAGAAGCCCAGGAGGTGGCCCTTGTGGCCTATAACTCAGCCGGGACCTCTCGCCCCACC
  CCGGTGGTCTTCTCAGAAAGCAGAGGCCCAGCTCTGACCAGACTCCATGCCATGGCCCGA
  GACCCTCACAGCCTCTGGGTAGGCTGGGAGCCCCCCAATCCATGGCCTCAGGGCTATGTG
  ATTGAGTGGGGCCTGGGCCCCCCCAGCGCGAGCAATAGCAACAAGACCTGGAGGATGGAA
  CAGAATGGGAGAGCCACGGGGTTTCTGCTGAAGGAGAACATCAGGCCCTTTCAGCTCTAT
  GAGATCATCGTGACTCCCTTGTACCAGGACACCATGGGACCCTCCCAGCATGTCTATGCC
  TACTCTCAAGAAATGGCTCCCTCCCATGCCCCAGAGCTGCATCTAAAGCACATTGGCAAG
  ACCTGGGCACAGCTGGAGTGGGTGCCTGAGCCCCCTGAGCTGGGGAAGAGCCCCCTTACC
  CACTACACCATCTTCTGGACCAACGCTCAGAACCAGTCCTTCTCCGCCATCCTGAATGCC
  TCCTCCCGTGGCTTTGTCCTCCATGGCCTGGAGCCCGCCAGTCTGTATCACATCCACCTC
  ATGGCTGCCAGCCAGGCTGGGGCCACCAACAGTACAGTCCTCACCCTGATGACCTTGACC
  CCAGAGGGGTCGGAGCTACACATCATCCTGGGCCTGTTCGGCCTCCTGCTGTTGCTCACC
  TGCCTCTGTGGAACTGCCTGGCTCTGTTGCAGCCCCAACAGGAAGAATCCCCTCTGGCCA
  AGTGTCCCAGACCCAGCTCACAGCAGCCTGGGCTCCTGGGTGCCCACAATCATGGAGGAG
  GATGCCTTCCAGCTGCCCGGCCTTGGCACGCCACCCATCACCAAGCTCACAGTGCTGGAG
  GAGGATGAAAAGAAGCCGGTGCCCTGGGAGTCCCATAACAGCTCAGAGACCTGTGGCCTC
  CCCACTCTGGTCCAGACCTATGTGCTCCAGGGGGACCCAAGAGCAGTTTCCACCCAGCCC
  CAATCCCAGTCTGGCACCAGCGATCAGGTCCTTTATGGGCAGCTGCTGGGCAGCCCCACA
  AGCCCAGGGCCAGGGCACTATCTCCGCTGTGACTCCACTCAGCCCCTCTTGGCGGGCCTC
  ACCCCCAGCCCCAAGTCCTATGAGAACCTCTGGTTCCAGGCCAGCCCCTTGGGGACCCTG
  GTAACCCCAGCCCCAAGCCAGGAGGACGACTGTGTCTTTGGGCCACTGCTCAACTTCCCC
  CTCCTGCAGGGGATCCGGGTCCATGGGATGGAGGCGCTGGGGAGCTTCTAGGGCTTCCTG
  GGGTTCCCTTCTTGGGCCTGCCTCTTAAAGGCCTGAGCTAGCTGGAGAAGAGGGGAGGGT
  CCATAAGCCCATGACTAAAAACTACCCCAGCCCAGGCTCTCACCATCTCCAGTCACCAGC
  ATCTCCCTCTCCTCCCAATCTCCATAGGCTGGGCCTCCCAGGCGATCTGCATACTTTAAG
  GACCAGATCATGCTCCATCCAGCCCCACCCAATGGCCTTTTGTGCTTGTTTCCTATAACT
  TCAGTATTGTAAACTAGTTTTTGGTTTGCAGTTTTTGTTGTTGTTTATAGACACTCTTGG
  GTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000760 unedited
  NGTCAAAATTTGTATACGACTCACTATAGGGCGGCCGCGAATCGGCACGAGGCAGGGGCT
  GGGCCAGAGGTGCCAACATGGGNGAAACTGAGGCTCGGCTCGGAAAGGTGAAGTAACTTG
  TCCAAGATCACAAAGCTGGTGAACATCAAGTTGGTGCTATGGCAAGGCTGGGAAACTGCA
  GCCTGACTTGGGCTGCCCTGATCATCCTGCTGCTCCCCGGAAGTCTGGAGGAGTGCGGGC
  ACATCAGTGTCTCAGCCCCCATCGTCCACCTGGGGGATCCCATCACAGCCTCCTGCATCA
  TCAAGCAGAACTGCAGCCATCTGGACCCGGAGCCACAGATTCTGTGGAGACTGGGAGCAG
  AGCTTCAGCCCGGGGGCAGGCAGCAGCGTCTGTCTGATGGGACCCAGGAATCTATCATCA
  CCCTGCCCCACCTCAACCACACTCAGGCCTTTCTCTCCTGCTGCCTGAACTGGGGCAACA
  GCCTGCAGATCCTGGACCAGGTTGAGCTGCGCGCAGGCTACCCTCCAGCCATACCCCACA
  ACCTCTCCTGCCTCATGAACCTCACAACCAGCAGCCTCATCTGCCAGTGGGAGCCCAGAC
  CTGAGACCCACCTACCCACCAGCTTCACTCTGAAGAGTTTCAAGAGCCCGGGCAACTGTC
  AGACCCAAGGGGACTCCATCCTGGACTGCGTGCCCAAGGACGGNCAGAGCCACTGCTGCA
  TCCCACGCAAACACCTGCTGNTGTACCAGAATATGGGCATCTGGGTGCANGCAGAGAATG
  CGCTGGGGACCAGCATGTCCCCACAACTGTGTCTTGATCCCATGGATGTTGTGAAACTGG
  AGCCCCCCATGCTGCGGACCATGGACCCCAGCCCTGAAGCGGCCCCCTCCAAGGCNAGCT
  GCCTACAGNTGTGCTGGAAGCCATGGCAACCCGGCCCTGACATAATAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000760 unedited
  GGGCGGGANNNGGGCCCCNCACCACNNNNNTTTNNNNNNNNNNNTTTTGACTTAGNAACG
  CGGNCCGCATNCTANGATCGNGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTACACCCAAAAGGGTCTATAAACAACAACAAAAACTGCAAACCAAAAAC
  TAGTTTACAATACTGAAGTTATAGGAAACAAGCCCAAAAGGCCATTGGGGGGGGCTGGAT
  GGAACATGATCTGGTCCTTAAAGTATGCAAATCGCCTGGGAGGCCCACCCTATGGAAATT
  GGGAGGAAAGGGAAATGCTGGTGACTGGAAATGGGGAAAGCCTGGGCTGGGGTAATTTTT
  AATCATGGGCTTATGGACCCTCCCCTTTTTTCCAGCTAGCTCAGGCCTTTAAAAGGCAGG
  CCCAAAAAGGGAACCCCAGGAAGCCCTAAAAGCTCCCCAGCGCCTCCATCCCATGGACCC
  GGATCCCCTGCAGGAGGGGGAAGTTGAACAAGGGCCCAAAAACACAGTCGTCCTCCTGGC
  TTGGGGCTGGGGTTACCAGGGTCCCCAAGGGGCTGGCCTGGAACCAAAGGTTCTCATAGG
  ACTTGGGGCTGGGGGTGAGGCCCGCCAAAAGGGGCTGAGTGGAGTCACAGCGGAAATAGT
  GCCCTGGCCCTGGGCTTGTGGGGCTGCCCAACAATTGCCCATAAAGGACCTGATCGCTGG
  TGCCAAACTGGGATTGGGGCTGGGTGGAAACTGCTTTTTGGTCCCCCTGGAGCACATAAG
  TTGGGACAGAAGGGGGAAGGCCCAGGTTTTTGAACTGTTTGGGGACTCCAGGGACCGGCT
  TTTTTAATCCCTCTCAACACTGTGACCTTGGTGAGGGGGGGGGGCCAAGGCCGGGCACTG
  GAAAGATCCTCTCCTGATGTGGGCCCCAGAACCCAGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000760
• Insert Size: 3000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000760.2, NP_000751.1
• RefSeq Size: 3003 bp
• RefSeq ORF: 2511 bp
• Locus ID: 1441
• Cytogenetics: 1p34.3
• Domains: FN3
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer
• Gene Summary: 'The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]'
  Transcript Variant: This variant (1) encodes isoform a.