Dystrobrevin alpha (DTNA) (NM_001390) Human Untagged Clone

CAT#: SC111623

DTNA (untagged)-Human dystrobrevin, alpha (DTNA), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DTNA
• Synonyms: D18S892E; DRP3; DTN; DTN-A; LVNC1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001390, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATTGAAGATAGTGGGAAAAGAGGAAATACCATGGCAGAAAGAAGACAGCTGTTTGCAGAGATGAGGG
  CTCAAGATCTGGATCGCATCCGACTCTCCACCTACAGAACAGCATGCAAGCTTAGGTTTGTTCAGAAGAA
  ATGCAATTTGCACCTGGTGGACATATGGAATGTCATAGAAGCATTGCGGGAAAATGCTCTGAACAACCTG
  GACCCAAACACTGAACTCAACGTGTCCCGCTTAGAGGCTGTGCTCTCCACTATTTTTTACCAGCTCAACA
  AACGGATGCCAACCACTCACCAAATCCATGTGGAGCAGTCCATCAGCCTCCTCCTTAACTTCCTGCTTGC
  AGCGTTTGATCCGGAAGGCCATGGTAAAATTTCAGTATTTGCTGTCAAAATGGCTTTAGCCACATTGTGT
  GGAGGGAAGATCATGGACAAATTAAGATATATTTTCTCAATGATTTCTGACTCCAGTGGGGTGATGGTTT
  ATGGACGATATGACCAATTCCTTCGGGAAGTTCTCAAACTACCCACGGCAGTTTTTGAAGGTCCTTCATT
  TGGTTACACAGAACAGTCAGCCAGATCCTGTTTCTCCCAACAGAAAAAAGTCACGTTAAATGGTTTCTTG
  GACACGCTTATGTCAGATCCTCCCCCGCAGTGTCTGGTCTGGTTGCCTCTTCTGCATCGACTAGCAAATG
  TGGAAAATGTCTTCCATCCGGTTGAGTGTTCCTACTGCCACAGTGAGAGTATGATGGGATTTCGCTACCG
  ATGCCAACAGTGTCACAATTACCAGCTCTGTCAGGACTGCTTCTGGAGGGGACATGCCGGTGGTTCTCAT
  AGCAACCAGCACCAAATGAAAGAGTACACGTCATGGAAATCACCTGCTAAGAAGCTGACTAATGCATTAA
  GCAAGTCCCTGAGCTGTGCTTCCAGCCGTGAACCTTTGCACCCCATGTTCCCAGATCAGCCTGAGAAGCC
  ACTCAACTTGGCTCACATCGTTGATACTTGGCCTCCCAGACCTGTAACCAGCATGAACGACACCCTGTTC
  TCCCACTCTGTTCCCTCCTCAGGAAGTCCTTTTATTACCAGGAGCTCTCCTCCCAAGGACAGTGAAGTAG
  AGCAGAACAAACTGCTGGCTAGGGCTGCTCCAGCTTTTCTGAAGGGCAAAGGGATACAGTACAGCCTGAA
  TGTGGCAGACAGGCTAGCTGATGAACATGTTCTCATCGGGTTGTATGTCAACATGCTCCGGAACAACCCC
  TCATGCATGCTTGAGAGTTCAAACCGGCTTGATGAAGAACACAGGCTAATTGCCAGGTATGCGGCAAGGC
  TGGCAGCAGAGTCCTCTTCGTCTCAGCCACCTCAGCAGAGAAGTGCTCCTGACATCTCTTTCACCATCGA
  TGCGAATAAGCAGCAAAGGCAGCTGATTGCTGAGCTAGAAAACAAGAACAGAGAAATCTTACAGGAGATC
  CAGAGACTTCGGCTAGAGCATGAACAAGCTTCTCAGCCCACGCCAGAGAAGGCACAGCAAAACCCCACCC
  TGCTGGCAGAACTCCGGCTCCTCAGACAGCGCAAAGATGAGCTGGAACAGAGAATGTCTGCTCTCCAGGA
  GAGCCGGAGAGAGCTAATGGTCCAGTTGGAGGGTCTCATGAAGCTACTAAAGACTCAGGGGGCAGGCTCT
  CCCCGCTCCTCCCCCAGCCACACCATCAGCAGGCCAATTCCCATGCCCATCCGGTCAGCGTCAGCCTGCT
  CCACCCCGACGCACACGCCGCAGGACTCCCTCACAGGAGTAGGGGGAGATGTACAAGAGGCATTTGCACA
  AAGTTCAAGAAGAAACTTAAGGAATGACTTGCTAGTGGCTGCAGATTCCATCACTAACACTATGTCCTCT
  CTTGTGAAAGAGCTGAATTCTGAGGTTGGGAGTGAAACAGAGAGTAATGTGGATTCTGAATTTGCACGGA
  CTCAGTTTGAGGATCTTGTTCCCTCACCAACCTCTGAAAAGGCTTTTCTAGCGCAAATCCATGCCCGAAA
  ACCTGGGTACATTCACAGTGGAGCTACCACAAGTACCATGCGTGGCGACATGGTTACGGAGGATGCAGAT
  CCCTATGTGCAGCCTGAAGATGAAAACTATGAAAATGACTCTGTCCGGCAGCTGGAGAATGAGCTCCAGA
  TGGAGGAATACCTGAAACAGAAGCTGCAAGATGAAGCTTATCAGGTCAGCTTGCAAGGTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001390 unedited
  GGGGGGTTGGGCCCCTTTTTTCCCCNNNGGGGTCAGGATTTGTATACGACTTACTATAGG
  CGGCCGCGAATTCGCCGAGGAAAGTTCATGCTGTCCCTTCATTGAATTTTAGAATGATTG
  AAGATAGTGGGAAAAGAGGAAATACCATGGCAGAAAGAAGACAGCTGTTTGCAGAGATGA
  GGGCTCAAGATCTGGATCGCATCCGACTCTCCACCTACAGAACAGCATGCAAGCTTAGGT
  TTGTTCAGAAGAAATGCAATTTGCACCTGGTGGACATATGGAATGTCATAGAAGCATTGC
  GGGAAAATGCTCTGAACAACCTGGACCCAAACACTGAACTCAACGTGTCCCGCTTAGAGG
  CTGTGCTCTCCACTATTTTTTACCAGCTCAACAAACGGATGCCAACCACTCACCAAATCC
  ATGTGGAGCAGTCCATCAGCCTCCTCCTTAACTTCCTGCTTGCAGCGTTTGATCCGGAAG
  GCCATGGTAAAATTTCAGTATTTGCTGTCAAAATGGCTTTAGCCACATTGTGTGGAGGGA
  AGATCATGGACAAATTAAGATATATTTTCTCAATGATTTCTGACTCCAGTGGGGTGATGG
  TNTATGGACGATATGACCAATTCCTTCGGNAAGTTCTCAAACTACCCACGGCAGTTTTTG
  AAGGTCCTTCATTTGGTTACACAGAACAGTCAGCCAGATCCTGTTTCTCCCACAGAAAAA
  GTCACGTTAAATGTTTCTTGGCACGNCTATGTCAGATCCTCCCCGCAGTGTCTGGTCTGG
  TTGCCTCTTCTGCATCGACTAGCAAATGTGGAAAATGTCTTCCATCCGGTTGAGTGTTCC
  TACTGCCACATGAGAGTATGATTGGATTCCGCTACCGATGCCACAGTGTCACACATACCA
  GCTCTGTCAAGACTGCTTCTGAAGGGACATGCCCGTGGTTCTCATACCACCAGCACCAAT
  GGAGGAGTCCCGCCTGGAAATCACCTGCTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001390 unedited
  TATGGACCGGCGGCCGCTATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAAACACACAC
  CTATGCACTACAAATCTGAGAACAAAAAGTTAGCTGCACTATAGTCATCAGGACACATCT
  TTAGGGGTGGGGGTCTGTCAGGAGCTGCTGGGTGTGGTGGTTCCTCTCTTCGGTGAGGCT
  GCTGCCAGGCTGCTGTCTTCCTCCTCTGTGTGGCCACAGGGCTCTCCATCATCACCAGTT
  TTCATGTTACTTTCATCATCTGTCTGACTATAGCTTGCTTGAGAGGAGTGTGATAAAAGG
  ATATTGCATTCAACCTTGCAAGCTGACCTGATAAGCTTCATCTTGCAGCTTCTGTTTCAG
  GTATTCCTCCATCTGGAGCTCATTCTCCAGCTGCCGGACAGAGTCATTTTCATAGTTTTC
  ATCTTCAGGCTGCACATAGGGATCTGCATCCTCCGTAACCATGTCGCCACGCATGGTACT
  TGTGGTAGCTCCACTGTGAATGTACCCAGGTTTTCGGGCATGGATTTGCGCTAGAAAAGC
  CTTTTCAGAGGTTGGTGAGGGAACAAGATCCTCAAACTGAGTCCGTGCAAATTCAGAATC
  CACATTACTCTCTGTTTCACTCCCAACCTCAGAATTCAGCTCTTTCACAAGAGAGGACAT
  AGTGTTAGTGATGGAATCTGCAGCCACTAGCAAGTCATTCCTTAAGTTTCTTCTTGAACT
  TTGTGCAAATGCCTCTTGTACATCTCCCCCTACTNCTGTGANGGAGTCCTGCGGCGTGTG
  CGTCGGGGTGGAGCAGGCTGACCCTGACCGGATGGGCATGGGAAATTGCCTGCTGATGGT
  GTGGCTTGGGGAAGAACCGGGAAACCCTCCCCCTGATCTTTATAGCTCATGAGACCCCTC
  ACTGGACATTAGCTCNTCCGGCTCTCTGGAGACAGAATTCTCTGTTCCACTATCTTTCGC
  TGCTGAGGGCCGGAGTCTGCACAGGTGGGGTTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001390
• Insert Size: 2580 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001390.3, NP_001381.2
• RefSeq Size: 6358 bp
• RefSeq ORF: 2232 bp
• Locus ID: 1837
• Cytogenetics: 18q12.1
• Domains: ZnF_ZZ
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1), also known as DTN1, encodes the longest isoform (1). Its 5' UTR has not been determined.