RFXANK (NM_003721) Human Untagged Clone

CAT#: SC111713

RFXANK (untagged)-Human regulatory factor X-associated ankyrin-containing protein (RFXANK), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RFXANK
• Synonyms: ANKRA1; BLS; F14150_1; RFX-B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111713 sequence for NM_003721 edited (data generated by NextGen Sequencing)
  ATGGAGCTTACCCAGCCTGCAGAAGACCTCATCCAGACCCAGCAGACCCCTGCCTCAGAA
  CTTGGGGACCCTGAAGACCCCGGAGAGGAGGCTGCAGATGGCTCAGACACTGTGGTCCTC
  AGTCTCTTTCCCTGCACCCCTGAGCCTGTGAATCCTGAACCGGATGCCAGTGTTTCCTCT
  CCACAGNNNNGCAGCTCCCTGAAGCACTCCACCACTCTCACCAACCGGCAGCGAGGGAAC
  GAGGTGTCAGCTCTGCCGGCCACCCTAGACTCCCTGTCCATCCACCAGCTCGCAGCACAG
  GGGGAGCTGGACCAGCTGAAGGAGCATTTGCGGAAAGGTGACAACCTCGTCAACAAGCCA
  GACGAGCGCGGCTTCACCCCCCTCATCTGGGCCTCCGCCTTTGGAGAGATTGAGACCGTT
  CGCTTCCTGCTGGAGTGGGGTGCCGACCCCCACATCCTGGCAAAAGAGCGAGAGAGCGCC
  CTGTCGCTGGCCAGCACAGGCGGCTACACAGACATTGTGGGGCTGCTGCTGGAGCGTGAC
  GTGGACATCAACATCTATGATTGGAATGGAGGGACGCCACTGCTGTACGCTGTGCGCGGG
  AACCACGTGAAATGCGTTGAGGCCTTGCTGGCCCGAGGCGCTGACCTCACCACCGAAGCC
  GACTCTGGCTACACCCCGATGGACCTTGCCGTGGCCCTGGGATACCGGAAAGTGCAACAG
  GTGATCGAGAACCACATCCTCAAGCTCTTCCAGAGCAACCTGGTGCCCGCTGACCCTGAG
  TGA
  
  Clone variation with respect to NM_003721.2
  187 g=>n;188 c=>n;189 a=>n;190 g=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003721 unedited
  GATTTTGTATCCGACTACTATAGGCGGCCGCGAATTCGGCACGAGGCCGGTCTCCAGTTT
  GCCTCCTGCTATATCCATTGGAAGAGAAAGTTTGTGACTTGGGCCCCCAAGTTTTGAGAG
  AACTGGGCTTTCGGCGCGGGGGGACAGAGGAGGCTCGTGGGGAGCTTTCCCCATGGAGCT
  TACCCAGCCTGCAGAAGACCTCATCCAGACCCAGCAGACCCCTGCCTCAGAACTTGGGGA
  CCCTGAAGACCCCGGAGAGGAGGCTGCAGATGGCTCAGACACTGTGGTCCTCAGTCTCTT
  TCCCTGCACCCCTGAGCCTGTGAATCCTGAACCGGATGCCAGTGTTTCCTCTCCACAGGG
  CAGCTCCCTGAAGCACTCCACCACTCTCACCAACCGGCAGCGAGGGAACGAGGTGTCAGC
  TCTGCCGGCCACCCTAGACTCCCTGTCCATCCACCAGCTCGCAGCACAGGGGGAGCTGGA
  CCAGCTGAAGGAGCATTTGCGGAAAGGTGACAACCTCGTCAACAAGCCAGACGAGCGCGG
  CTTCACCCCCCTCATCTGGGCCTCCGCCTTTGGAGAGATTGAGACCGATCGCTTCCTGCT
  GGAGTGGGGTGCCCGACCCCCACATCCTGTCAAAAGAGCGAGAGAGCGCCCTGTCGCTGG
  CCCGCACAGGCGGCCTCCACAAGACATTGTGGTGCTGCTGCCGGAGCGTGACGTGGACAT
  CAACATCTATGACTGGAAATGGATGGACGCCACTGCTGGACGCTGTGCCGCGGGACCACG
  TGAAATGCGTTGAGGCCTTGCTTGCCCCGAGCCGCTGACCTCACCCCCGAAAGCGCACTC
  TGTCTACACCCCGATGAACCCTGCCGGGGCCCTGGGTATACCGGAAGGGCACCAGGGGAT
  TGAGAACCCCATTCTCAGTTTTTTCCAAGCACCTGGGGCCCGGTGACCTCGATGAAGCCG
  GCTGCCGGGCACTCAACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003721 unedited
  GGAAAAAAANTTACTTGNACCGCGCCGCAATCTANATCGAGTTTTTTTTTTTTTTTTTTC
  TGCACAGAAGTTTATTGGTTCCTCTTGGGAAGGGTCCCCTCCCACCACCTGTCCAGAAGC
  TGCCTTTGAAGTCAGTTCTGGGTTTCCCCAGCTCTGGCTGACCATTTTGTTCCCTGAGTG
  TCTGAGTCCCCGGCAGGCGGCCTTCACTCAGGGTCAGCGGGCACCAGGTTGCTCTGGAAG
  AGCTTGAGGATGTGGTTCTCGATCACCTGTTGCACTTTCCGGTATCCCAGGGCCCACGGC
  AAGGTCCATNCGGGNTGTANCCAGAAGTCGCTTCGGTGGTGAGGTCAGCGCCTCGGGCCA
  GCAGGCCTCAACGCATTTTACGTGGTTCCCGCGCCAGCGTACAGCAGTGGCGTCCCTCCA
  TTCCATCATAGAATGTGATGTCCACGTNACGCTCCAACAGCAGCCCCACAATGTCTGTGG
  TACCGCCTGTGCTGGCACACCACAGGCCGCTTTTTTGCTTCTTTTGCCAGATGTGGGGGT
  CGCACCCCACTCCACCAGGAAACGAACCGGTCTAATTTCTTCCAAAGCCGAGGGCCAAAT
  GAGGGGGGGTGAAACCGCCCTCCTTTGGCTTGGTTGACCAAGTTTACCCCTTTTCCCAAA
  GGCCTCTTAACTGGGGCCAATTCCCCTTTTGCTTGAAACTTGGGGAAGGACCGGGATTTT
  AGGGGGGCCGGAAAAAATTAAACCTCTTTTCCCTTCCTTCCCGGTTGGGAAAAATGGGGG
  AATGCTTTAGGGAACCTCCCCTTGGGAAAAGGAAAACCCGGGTTCTCGGTTAAGAATTCC
  AAGCCCCAGGGGGGGCGGGAAAAAAACCGAGGCCCACCTGGGTGGAACCTTTTGAAGCCC
  CTTTTCCGGGGTTTTAGGGGCCCCCAATTTAGAGCAGGGGTTCTTGGGTTTAAAAAAATC
  TTTTCGACGGGGGGGACCTCCGGGAAAAAATCCCAAAATCCTTTTGTTCCCCCGCCAGAA
  CCATTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003721
• ORF Size: 783 bp
• Insert Size: 1120
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003721.2, NP_003712.1
• RefSeq Size: 1438
• RefSeq ORF: 783
• Locus ID: 8625
• Domains: ANK
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Antigen processing and presentation, Primary immunodeficiency
• Gene Summary: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) encodes the longest isoform (a).